More information on Glucosamine for those interested.

[Guest guest]

For those interested, here's more information about "Glucosamine." If anyone

wants to know the source of the info, email me at: Adamson

Every day your joints endure an enormous amount of stress from physical

activity, including walking, lifting, and typing. Despite this heavy and

constant use, we take our joints for granted and expect them to function

trouble-free for several decades. However, more than 50 million people in the

U.S. and more than 6 million in Canada suffer from some form of joint problem.

The situation is worse for athletes and those who have high amounts of physical

stress at work and at home. To help maintain healthy joints, this product is a

blend of glucosamine, manganese, vitamin C, and silicon-the building blocks for

healthy cartilage.*

 

Cartilage -

Cartilage is the protective layer that cushions and lubricates the joints. Over

the years, the cartilage in our joints is gradually worn down due to normal

physical activity. The body rebuilds the cartilage as it is worn and replaces

shock-absorbing synovial fluid, so the joints are always protected. For various

reasons, however, the production of new cartilage and synovial fluid can fall

behind demand. Because of poor blood supply, lesions to articular cartilage do

not heal at the same rate as other tissue in the body; cartilage is rebuilt

slowly. And if components of the substances used for cartilage repair are in

short supply, the recovery from damage can be slowed even more.

 

Glucosamine -

Glucosamine, an aminosugar, is an important precursor in the biosynthesis of

cartilage. Specifically, it is a building block of proteoglycans1-protein

molecules with a high content of bound carbohydrate. Proteoglycans and collagen

compose the majority of the cartilage matrix.* Proteoglycans are essential for

healthy cartilage because they bind the water that lubricates and cushions the

joint.* When the articular cartilage degenerates, joint pain and osteoarthritis

may result.

 

In addition to its role as a biochemical precursor, glucosamine is believed to

play a role in regulating cartilage formation and normalizing cartilage

metabolism by encouraging higher production of collagen and proteoglycans.*

Glucosamine also stimulates synovial production of hyaluronic acid, which is

responsible for the lubricating and shock-absorbing properties of synovial

fluid.*

 

Numerous double-blind clinical studies have shown the efficacy of glucosamine

supplements in maintaining healthy cartilage, healthy joints, and full range of

motion in the short-term.2-8* More recently, a three-year study was published

showing that joint space increased in the glucosamine-treated group, while it

continued to decrease in the placebo group indicating that the protective

cartilage was better maintained in those who used glucosamine.9 Additional

studies have demonstrated that glucosamine, taken orally, is well-absorbed and

diffuses into tissues, including the articular cartilage.10-12

 

Turmeric Extract -

Turmeric, the powdered root of the plant, Curcuma longa L., has long been used

as a spice (e.g., in curry) and as a natural food colorant.13 Curcumin and

related compounds (collectively known as curcuminoids) have been isolated and

identified in turmeric. They are phenolics, which have significant antioxidant

properties.14*

 

Manganese, Vitamin C, and Silicon -

Optimal joint health also involves three additional important ingredients.

Manganese is required for enzymes involved in the biosynthesis of

proteoglycans.* Vitamin C is essential for the reactions necessary to collagen

formation,* and silicon is required for proper collagen formation and ultimately

cartilage composition.*

 

The combination of turmeric extract with glucosamine sulfate, manganese, vitamin

C, and silicon represents a more comprehensive approach to joint health. Over

the long term, glucosamine sulfate, vitamin C, manganese, and silicon help to

maintain healthy cartilage.* And glucosamine sulfate promotes the incorporation

of sulfur, a component of all protein, into the cartilage matrix.

 

This product incorporates a full 2000 mg per day of high quality glucosamine

sulfate, the highest dose in the industry. Then we combine this with turmeric

extract for faster action and vitamin C, manganese, and silicon for

comprehensive joint health. It is laboratory tested and potency guaranteed.

Meets USP specifications for uniformity and disintegration where applicable.

Take tablets, twice daily, preferably with meals.

 

* These statements have not been evaluated by the Food and Drug Administration.

This product is not intended to diagnose, treat, cure, or prevent any disease.

 

REFERENCES

 

 

1. Karzel K and Domenjoz R, Pharmacology, 1971; 5:337-45.

2. Pujalte JM, Llavore EP, Ylescupidez FR, Curr Med Res Opin, 1980; 7:110-14.

3. Lopes Vaz A, Curr Med Res Opin, 1982; 8:145-49.

4. Muller-Fabender H, et al., Osteoarth Cartilage, 1994; 2:61-69.

5. Crolle G, D'Este E, Curr Med Res Opin,1980; 7:104-09.

6. Dovanti A, Bignamini AA, Rovati AL, Clin Therapeutics, 1980; 3:266-72.

7. Pujalte JM, Llavore EP, Ylescupidez FR, Curr Med Res Opin, 1980; 7:110-14.

8. Tapadinhas MJ, Rivera IC, Bignamini AA, Pharmatherapeutica, 1982; 3:157-68.

9. Reginster JY, et al., Lancet, 2001; 357:251-56.

10. Vaz AL, Curr Med Res Opin, 1982; 8:145-49.

11. Fabender HM, et al., Osteoarthr and Cartilage, 1994; 2:61-69.

12. D'Ambrosio E, et al., Pharmatherapeutica, 1981; 1:504.

13. Stoner GD, Mukhtar H, J Cell Biochem, 1995; Suppl 22:168-80.

14. Sreejayan R, J Pharm Pharmacol, 1994; 46:1013-16.

 

 

 

Message: 4

Sat, 01 Feb 2003 19:57:45 -0000

"saktidasa <saktidasa" <saktidasa

Glucosamine is made from shellfish.

 

Although it isn't on the packet-----Tony.

[Guest guest]

, "Adamson" <adamson@s...> wrote:

 

Namaste,

 

As a vegetarian I cannot eat the product of shellfish, in there any

other stuff made, artificially....I have been taking glucosamine for

years now I find out I have been polluting myself, because it isn't

on the package...ONS....Tony.

[Guest guest]

Hello

 

I was reading the archives and noticed this message regarding

glucosamine. There is now a vegan/vegetarian source of glucosamine

available!

 

See:

 

http://www.vegetarianvitamin.com/catalog_126.html

 

 

With metta,

 

Ryan

 

 

, "saktidasa <saktidasa>"

<saktidasa> wrote:

> , "Adamson" <adamson@s...>

wrote:

>

> Namaste,

>

> As a vegetarian I cannot eat the product of shellfish, in there any

> other stuff made, artificially....I have been taking glucosamine

for

> years now I find out I have been polluting myself, because it isn't

> on the package...ONS....Tony.