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Grapefruit and metformin

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Below is from Fresh Produce Newsletter.

Melly

==============

 South Africa: Grapefruit bad news for diabetics

 

Grapefruit juice can be bad for people on a certain diabetes medication, a

pharmacologist from the University of KwaZulu-Natal has discovered.

 

Dr Peter Owira's research found that patients with type 2 diabetes who are

taking the medication metformin (Bigsens, Forminal, Glucophage) are at risk of

developing high lactic acid levels, considered dangerous for the body.

 

Grapefruit juice is a popular choice among type 2 diabetics because it improves

glycaemic control and helps patients reduce weight.

 

However, tests on three groups of rats found that although the combination of

metformin and grapefruit juice lowered blood glucose levels, it also increased

lactic acid levels.

 

Endurance athletes usually experience this as painful cramps, but it can lead to

perspiration, fevers, and even death, warned Owira, whose research focuses on

the molecular pharmacology of natural products.

 

" Dr Owira cautions such patients against consuming the fruit while on the

medication metformin, " said the university.

 

Owira said the study did not concentrate on what a safe window period would be

for consuming grapefruit juice while on the medication.

 

Source:www.health24.com

 

 

Publication date: 10/9/2009

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