New Study Shows Role of Role of Reactive Oxygen in the Cancer

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New Study Shows Role of Role of Reactive Oxygen in the Spreading of

Cancer

 

Scientists at the Burnham Institute for Medical Research in California

say they've discovered reactive oxygen plays a key role in cancer

metastasis.

The researchers, led by Professor Sara Courtneidge, said they determined

reactive species, such as superoxide and hydrogen peroxide, help form

invadopodia which are cellular protrusions implicated in cancer cell

migration. They found inhibiting reactive oxygen reduces invadopodia

formation, thereby limiting cancer cell invasion.

 

Editor's Notes: In aerobic organisms like humans, oxygen is converted to

water at the end of the respiratory chain in the mitochondria.

Mitochondria are the " power plants " in our cells that provide the energy

needed to maintain normal body function and metabolism.  However, in

this same mitochondria respiratory chain, oxygen is " partially reduced "

to form superoxide.

 

Antioxidants such as Vitamins A, C and E, superoxide dismutase, and

carotenoids such as alpha and betacarotene, lutein and zeaxanthin help

protect us by neutralizing reactive oxygen molecules and other free

radicals.

 

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