Higher fibre shown to reduce oestrogen levels

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From: "califpacific" Tue, 19 Oct 2004 13:37:49 -0000 Higher fibre shown to reduce oestrogen levelshttp://nutraingredients.com/news/ng.asp?id=55490 & n=dh293 & c=wokvpgxagwnympqHigher fibre shown to reduce oestrogen levels19/10/2004 - An international team has demonstrated that women with ahigher intake of dietary fibre have lower circulating oestrogenlevels, a factor associated with lower risk of breast cancer.They say their findings, which offer direct evidence of theassociation between fibre and the hormone, could lead to a dietarystrategy for lowering a woman's risk of breast cancer.Breast

cancer rates have risen in recent decades to become the mostcommon cancer among women in the European Union and US. Britain hasone of the highest breast cancer death rates in the world, accordingto Breast Cancer Research, with one woman in nine developing thedisease during her lifetime.There have already been several studies investigating the relationshipbetween dietary fibre and breast cancer but researchers have not beenable to show a true and unequivocal cause-and-effect relationshipbetween fibre and breast cancer risk.In a new study, researchers from the Keck School of Medicine of theUniversity of Southern California in Los Angeles, the University ofHawaii in Honolulu, and the University of Helsinki in Finland examinedblood oestrogen levels in around 250 Mexican-American women, an ethnicgroup in which dietary fibre intake is higher on average than in mostother populations."Latinas enrolled in the Multiethnic

Cohort Study have lower breastcancer rates than any major racial/ethnic group in the US. Even afteradjusting for known risk factors, their incidence rate is still 20 percent less than white women, who have been the focus of the majority ofearlier research and whose dietary fibre intake is generally not thathigh," explained the study first author Kristine Monroe, apostdoctoral fellow in the Keck School's department of PreventiveMedicine.Dietary fibre intake was quantified by a food frequency questionnaireadministered at the time of the blood draw and by using biomarkers ofdietary fibre intake found in the blood samples.Speaking yesterday at the American Association for Cancer Research(AACR) conference, 'Frontiers in Cancer Prevention Research', theresearchers said they found the two female hormones estrone andestradiol dropped sharply as dietary fibre intake increased.In addition, as dietary fat intake increased

in the women studied, sodid the hormone levels."However, when dietary fibre and fat are both included in thestatistical model, only dietary fibre remains a significant predictorof hormone levels," said Monroe.The next step is to see if a higher intake of dietary fibre in thesewomen leads to a lower incidence of breast cancer, she added."This study provides clear evidence of an association between dietaryfibre intake and circulating hormone levels in postmenopausal Latinawomen and potentially provides a dietary means for lowering a woman'srisk of breast cancer," concluded the researchers.Earlier this year a Swedish team reported that postmenopausal women inthe highest quintile of fibre intake had a 40 per cent lower risk ofbreast cancer than those with the lowest. Combining high fibre with alow fat diet reduced the risk even further.Copyright -Please pass this

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