Guest guest Posted July 6, 2003 Report Share Posted July 6, 2003 ANTIDEPRESSANT MAY COOL HOT FLASHES Doctors say the antidepressant paroxetine may help reduce hot flashes in menopausal women. Researchers at 18 U.S. centers found a slow-release form of the anti-anxiety drug, sold under the brand name Paxil, reduced hot flashes by up to 65 percent, or 3.3 flashes per day. The researchers note in the Journal of the American Medical Association hot flashes traditionally have been treated with estrogen and progestin hormone supplements. The therapy can reduce the frequency of the common symptom of menopause by 80 percent to 90 percent. However, a large study has indicated the hormone treatment may be tied to an increased risk of heart attack, stroke, blood clots and breast cancer. Paroxetine is " the best nonhormonal drug we know about right now, " said lead author Dr. Vered Stearns, assistant professor of oncology at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center. " If a woman wants to try nonhormonal therapy, she will know within days whether it's going to work. " DRUG FOUND EFFECTIVE AGAINST SLEEP DISORDER Scientists say the antidepressant drug mirtazapine shows promise as a treatment for a potentially life-threatening sleep disorder called sleep apnea. In tests at the University of Illinois in Chicago, the researchers found mirtazapine significantly reduced symptoms of the disorder that affects some 20 million Americans, who may stop breathing for 10 seconds or more during sleep. In the study, the drug cut in half the number of times breathing stopped or slowed during sleep and reduced by 28 percent the number of times sleep was disrupted. All 12 participants showed improvement., the investigators say. " The drug provided the largest benefit and the most consistent improvement of any pharmaceutical therapy tested in controlled studies to date, " said David Carley, professor of medicine, pharmacology and bioengineering at the Center for Sleep and Ventilatory Disorders. The results were presented at the annual meeting of the Associated Professional Sleep Societies in Chicago. GUIDELINES OFFERED FOR TREATING CHILDREN'S BRAIN INJURIES Health care experts have come up with the first guidelines for treating traumatic brain injuries in children. The recommendations, based on the review of more than 700 journal articles, were published in Pediatric Critical Care Medicine, Critical Care Medicine and the Journal of Trauma. " There's an enormous amount of information out there about what works and what doesn't in treating pediatric brain injury, " said principal investigator Dr. Randy Chesnut, associate professor of neurological surgery at the Oregon Health and Science University School of Medicine. " We not only want to publish guidelines that bring together all the best practices, we want to remove obstacles to putting those guidelines to work saving lives. " In the past, treatment could vary depending on such factors as where the child lived, where and how he was taken for treatment, who administered treatment and what equipment was available. The guidelines aim to eliminate such at-times life-threatening differences, said Nancy Carney, assistant professor of medical informatics. REDUCING HEART-THREATENING CALCIUM DEPOSITS Investigators have found lifestyle changes and statin therapy can slow or even reduce potentially dangerous calcium deposits in the coronary arteries. The tests were conducted on patients without symptoms but at risk for heart disease. " The rate of progression of calcium scores was less, " said Dr. Victor Goh, consultant cardiologist at Matilda International Hospital in Hong Kong. " Statin therapy, in addition to lifestyle modification, induced a 32 percent rate of reduction in the coronary calcium scores in asymptomatic patients. " The study shows early detection and treatment can prevent coronary artery disease from progressing -- and in some cases, allows the disease to regress, Goh said at the American Heart Association's Second Asia Pacific Scientific Forum in Honolulu. © Copyright 2003 by United Press International. All rights reserved. *********************************************************************** Quote Link to comment Share on other sites More sharing options...
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