Guest guest Posted July 10, 2002 Report Share Posted July 10, 2002 In a message dated 7/9/02 11:43:19 AM, EMillerReid writes: << LIFE EXTENSION WEEKLY UPDATE EXCLUSIVE Successful aging greater in children of long-lived parents If long life is primarily genetically determined, it would follow that the offspring of long-lived individuals would show the signs of " successful aging " , defined as the absence of disability and disease and the maintenance of a high level of cognitive and physical functioning. To add evidence to this hypothesis, researchers at the University of Southern Denmark, the University of Minnesota and the Max Planck Institute for Demographic Research in Germany used three Danish population-based surveys to determine whether parental age was associated with successful aging in their children. The study, published in the May 13 2002 issue of the journal Epidemiology (http://www.epidem.com/), collected data on parental age at death, physical functioning as measured by hand-grip strength, cognitive functioning as determined by several test scores, and the presence of various diseases in 9,285 participants. The age of death of the father and mother of each participant was averaged into a mean parental age at death. Grip strength was mildly positively associated with every additional ten years of life lived by the parents of the participants. Each ten year increment of parental life was correlated with a 20% reduction in the child's odds of experiencing heart failure, stroke, high blood pressure, ischemic heart disease, diabetes, or health rated as fair to very poor. These associations were observed mainly in individuals 70 to 90 years of age. Age-related differences in health in younger individuals may not have been large enough to detect effects of parental longevity. Cancer, osteoarthritic, osteoporosis and pulmonary disease were not associated with the life span of the subjects' parents in any age groups. This study lends further support to the influence of heredity on successful aging. Although genetic manipulation as a means to control the aging process in humans is not yet available, there exist interventions such as nutritional supplementation, dietary considerations and exercise which help promote successful aging for everyone, regardless of their genetic heritage. WHAT'S HOT Centenarian siblings also long-lived In the latest of a series of National Institute on Aging-supported studies, research published in the June 11 2002 issue of the journal Proceedings of the National Academy of Sciences (http://www.pnas.org/) found that sisters of individuals who survived 100 years or more were eight times more likely and brothers were seventeen times more likely to also live to the age of one hundred in comparison with U.S. citizens born in 1900. Data was gathered from 444 families of centenarians, which included 2,092 siblings. The information was analyzed by researchers participating in the New England Centenarian Study in Boston, led by Thomas Perls MD. Earlier research led by Dr Perls located a region on chromosome 4 that is likely to predispose its inheritors to long lives. The study also found that sisters of centenarians had half the risk of dying at any age compared to the national average and that brothers had similar rates except during the teen and young adult years. Although survival to advanced ages may be partly the result of socioeconomic or environmental factors, the differences in mortality between social groups tend to disappear in old age, lending support to genetic factors involved in exceptional longevity. http://ezines.lef.org?p=151069092 or http://www.lef.org/whatshot/#csal >> Namaste, Liz <A HREF= " http://www.csun.edu/~ecm59556/Healthycarb/index.html " > http://www.csun.edu/~ecm59556/Healthycarb/index.html</A> Quote Link to comment Share on other sites More sharing options...
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