MSM - Sulfur In Human Nutrition and Applications In Medicine

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Sulfur in Human Nutrition and Applications in Medicine

Journal: Altern Med Rev 2002 Feb;7(1):22-44

 

Author: Parcell S.

 

Affiliation: ND candidate, 2002, Bastyr University, Seattle, WA; Research

Associate, American Institute for Biosocial and Medical Research (AIBMR) in

Tacoma, WA; Correspondence address: 6210 35th Ave NE, Seattle, WA 98115; e-mail:

steveparcell

 

NLM Citation: PMID: 11896744

 

Because the role of elemental sulfur in human nutrition has not been studied

extensively, it is the purpose of this article to emphasize the importance of

this element in humans and discuss the therapeutic applications of sulfur

compounds in medicine.

 

Sulfur is the sixth most abundant macromineral in breast milk and the third most

abundant mineral based on percentage of total body weight. The sulfur-containing

amino acids (SAAs) are methionine, cysteine, cystine, homocysteine, homocystine,

and taurine.

 

Dietary SAA analysis and protein supplementation may be indicated for vegan

athletes, children, or patients with HIV, because of an increased risk for SAA

deficiency in these groups. Methylsulfonylmethane (MSM), a volatile component in

the sulfur cycle, is another source of sulfur found in the human diet. Increases

in serum sulfate may explain some of the therapeutic effects of MSM, DMSO, and

glucosamine sulfate.

 

Organic sulfur, as SAAs, can be used to increase synthesis of

S-adenosylmethionine (SAMe), glutathione (GSH), taurine, and N-acetylcysteine

(NAC). MSM may be effective for the treatment of allergy, pain syndromes,

athletic injuries, and bladder disorders. Other sulfur compounds such as SAMe,

dimethylsulfoxide (DMSO), taurine, glucosamine or chondroitin sulfate, and

reduced glutathione may also have clinical applications in the treatment of a

number of conditions such as depression, fibromyalgia, arthritis, interstitial

cystitis, athletic injuries, congestive heart failure, diabetes, cancer, and

AIDS.

 

Dosages, mechanisms of action, and rationales for use are discussed. The low

toxicological profiles of these sulfur compounds, combined with promising

therapeutic effects, warrant continued human clinical trails. in

 

 

Terry suttles

 

 

 

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