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Viral mouthwash may curb precancerous mouth lesions

 

FRANKFURT (Reuters Health) - A mouthwash that contains a modified respiratory

virus known as ONYX-015 may help prevent precancerous mouth lesions from

becoming cancerous, US researchers said at a cancer therapeutics conference here

on Thursday.

 

They reported the results from a small study of 22 patients.

 

" This treatment prevented progression in one-third of the patients in the

study, " said investigator Dr. Ezra E. W. Cohen, an instructor in medical

oncology at the University of Chicago, Illinois. " The changes were obvious

clinically, the biopsies were normalised. "

 

Cohen told Reuters Health the treatment was well tolerated and that few

toxicities developed during the study. However, future studies will need to

determine the amount of time that treatment should continue. In the current

research, patients' lesions worsened when treatment was discontinued.

 

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