Neurological Disorders and hidden Gluten Sensitivity

January 30, 2003

One hundred and ninety-seven persons, including fifty-three with a neurological

disorder of unknown origin were studied for gluten sensitivity They were tested

for anti-gliadin antibodies––gliadin being a fractional part of gluten which in

turn is a part of wheat. Fifty-six percent of the fifty-three people with a

neurological disorder of unknown origin showed an antibody response to the

gliadin. When the 56 percent were retested with duodenal biopsies––the

definitive diagnostic test for celiac disease/gluten sensitivity–– there was

evidence of celiac lesions in 35 percent, and non-specific duodenitis in 38

percent. Only 26 percent had no lesions. In other words 74 percent were wheat

sensitive.

Whether it is actually the wheat gluten that aggravates the neurological

disorder or the uptake of gut toxins and/or protein fragments from increased

intestinal permeability is unknown. The question is, what other mental disorders

may be affected by diet through gluten sensitivity? This could have potential

impact on mental disorders throughout North America, which has always been a

wheat dependent society.

Clinical Pearls News April 1996

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