Dietary Fat in Regards to Coronary Heart Disease

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Dietary Fat In Regards to Coronary Heart Disease Mortality JoAnn Guest Aug

04, 2003 16:36 PDT

Dietary Fats and Coronary Heart Disease Mortality

 

 

Medical Abstract Title:

 

Dietary Fats and 16-year Coronary Heart Disease Mortality in a Cohort of

Men and Women in Great Britain

 

Author:

 

Boniface DR, Tefft ME

 

Source:

 

Eur J Clin Nutr. 2002;56(8):786-792.

 

Abstract:

 

OBJECTIVE: The paper aims to investigate the relationships of dietary

fats to subsequent coronary heart disease (CHD) mortality in men and

women while taking account of other CHD-related behaviours.

 

DESIGN: A cohort of randomly selected men and women were interviewed in

1984-85 and monitored subsequently for 16 y for deaths. The interview

covered health, health-related behaviours, physical measurements,

socio-demographic details and a dietary questionnaire. Appropriate

exclusions left 1225 men and 1451 women aged 40-75 with 98 and 57 CHD

deaths, respectively. Saturated, polyunsaturated and total fat intakes

were estimated.

 

SETTING: The sample was randomly selected from households in Great

Britain. The interviews took place in participants' own homes.

 

RESULTS: Not consuming alcohol, smoking, not exercising and being

socially disadvantaged were related to high saturated fat intake and CHD

death. Cox survival analyses adjusting for these factors found that a

level of saturated fat 100 g per week higher corresponded to a relative

risk for CHD death for men of 1.00 (0.86-1.18) and 1.40 (1.09-1.79) for

women. This difference between the effects of saturated fat in men and

women was statistically significant (P=0.019). Results are also reported

for total fat and the relative effects of polyunsaturated and saturated

fats.

 

CONCLUSIONS: Strong evidence was found for the within cohort

relationship of dietary fat and CHD death in women while no evidence was

found for a relationship in men. Possible explanations for this are

discussed.

 

SPONSORSHIP: This study was supported by University of Hertfordshire

using funding made available by

the UK Higher Education Funding Council.

 

http://www.enzy.com/abstracts/display.asp?id=3702

 

 

 

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