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What Is The Laetrile Therapy

 

http://www.dob17.com/controlcancer/information/laetrile.htm

 

Metabolism is the total function of our body. In order for our body to

function properly, all its attributes (physical, mental, and spiritual) must

work in harmony. Total care is the goal of the Metabolic Therapy, has

several elements that are utilized in order to provide our human organism

the best environment to combat the disease and regain health. The Metabolic

Therapy, our primary nontoxic cancer treatment, is based on the use of

laetrile, digestive enzymes, immuno-stimulants, mega-doses of vitamins and

minerals, spiritual, nutritional, and psychological support. The metabolic

Therapy is not complete without its chief anti-tumor agent.

 

Laetrile (B-17) is a natural chemotherapeutic agent found in over 1,200

plants, particularly in the seeds of common fruits such as apricots,

peaches, plums, and apples.

 

It is a diglucocide with a cyanide radical that is highly " bio-accessible " .

This means that it penetrates through the cellular membrane reaching high

intracellular concentrations easily. The cyanide radical is what preoccupies

most scientists, but it has been proved that Laetrile (B-17) is completely

nontoxic. Our own experience with hundreds of patients give us complete

confidence that there is no danger. The normal cells in our organism contain

an enzyme called Rodhenase which " neutralizes " the laetrile.

 

This enzyme does not allow the laetrile to release the cyanide. In this way,

laetrile only serves as a glucose to healthy cells providing energy.

Malignant cells do not contain this enzyme. In the absence of Rodhenase, the

laetrile is activated liberating the cyanide radical inside the malignant

cell causing its destruction. This is the way God creates things:

only cancerous cells are destroyed but normal ones are not affected.

 

As the laetrile attacks unhealthy cells, it transforms into silicate which

is much like aspirin. It contributes greatly to pain control. Though it has

limitations in certain cancers, it is extremely effective in the most common

tumors such as Carcinoma of the Lung, Breast, Prostate, Colon, and Lymphomas

..

 

A highly publicized clinical trial conducted by the National Cancer

Institute (NCI) in 1981, tried unsuccessfully to prove that Laetrile was

ineffective and toxic. Today, Laetrile occupies a position on the " front

lines " of Alternative Cancer Therapies. We have found Laetrile to be

effective on people that have active cancer; but that is not its only

function. For prevention of cancer and the maintenance of remission there is

nothing as effective as Laetrile. Its non-toxicity permits its use

indefinitely in the prevention of relapses and the prevention of metastases.

Surgery, Radiation, and Chemotherapy can only be administered for a limited

time, afterwards patient are left without any protection.

 

There is no doubt that the struggle against cancer is the greatest challenge

that medical science has ever faced. There is no other disease to which more

money is devoted, or to which scientists dedicate more hours of study. The

magnitude of the cancer problem may be demonstrated by a few statistics. One

of three Americans will develop Cancer during their lifetime, and one out of

four will die from it. This year, over 989,200 people will die from cancer

in the USA .

 

Cancer is increasing in all age categories. Lifestyle, nutrition, food

additives, pesticides, ultraviolet radiation and a variety of other

environmental factors are directly implicated. With certain exceptions,

cancer appears to be a man-made disease and is therefore a preventable

disease. It is now apparent that cancer may be caused by an almost limitless

variety of physical, chemical and biological agents. Although it is true

that surgery an radiotherapy are capable of curing some patients with

localized tumors and that chemotherapy has achieved cures in some malignant

tumors, the general mortality rate from cancer is increasing. Many patients

cannot be exposed to chemotherapy, surgery or radiotherapy because of the

undesirable effects over their poor physical condition resulting from

cancer.

 

All this justifies, and even makes imperative, the search for new substances

with anti-tumoral effects and ideally with little or no toxicity in

therapeutic dosages. In the last 15 years, several herbs and hormonal

substances have been discovered with such characteristics. Therefore, many

patients who formerly could not be benefited or alleviated medicinally may

not be exposed to useful anti-neoplastic treatments. Nature provides an

arsenal to destroy tumors or at least to neutralize their growth.

 

The leading natural therapy is Amygdalin, better known as Laetrile, a

product made with the purest amygdalin, obtained from apricot kernels

(bitter almonds), through an exclusive extraction process.

 

What Is The Nature Of Cancer?

 

In order to intelligently discuss any form of therapy, it is essential to

know something about the nature of the disease. Cancer has been defined as a

cellular tumor, the natural course of which is fatal. Another term for

cancer is a malignant neoplasm . Neoplasm refers to a progressive

uncontrolled new growth of tissue.

 

The term tumor may be correctly applied to any neoplasm, benign or

malignant. A benign tumor is one that lacks the ability to invade other

tissues and does not spread or metastasize , and for the most part can be

surgically removed. A malignant tumor or cancer is characterized by it's

ability to invade tissue, metastasize, the cells are less differentiated (a

process known as anaplasia , in which the tumor cells do not resemble those

of the parent tissue), and ultimately results in the death of the victim.

The term metastasis refers to the transfer or spread of the cancer from one

organ or part to another not directly connected with it. Thus, tumor cells

may originate in one part of the body ( primary tumor ) and suddenly appear

in some other organ or distant part of the body ( secondary tumor ).

 

Metastases are a significant factor in bringing about the death of the

patient. There are over 100 different clinical types of cancers which are

frequently divided into the two broad categories of carcinomas and sarcomas

.. Carcinomas are malignant new growths of epithelial cells and may involve

the breasts, digestive tract, uterus, skin, etc. Sarcomas are malignant new

growths of connective tissue and involve such organs as bone, muscle,

nerves, lymph glands, etc. Hodgkin's disease and melanomas are a type of

sarcoma. In general, tumors are classified according to the cell type

involved, and occasionally they are of the mixed type containing both

epithelial and connective elements. The leukemias are another type of

malignancy that involves a progressive proliferation of the blood forming

organs of the body. Leukemia is sometimes referred to as cancer of the

blood.

 

The typing and grading of malignant tumors becomes very complicated and goes

far beyond the intent of this publication. In order to explain some of the

more basic elements of carcinogenesis, it is necessary to deal with some of

the fundamental of cell structure and function. The major subdivisions of a

cell include the nucleus and the surrounding cytoplasm . The nucleus is the

primary control center of the cell. Chromosomes are a structure in the

nucleus comprised of a linear thread of a nucleic acid known as

deoxyribonucleic acid (DNA) . Chromosomes appear as elongated threadlike

bodies in the nucleus and are clearly visible only when the cell is

undergoing division. The chromosomes are comprised of nucleic acid and

protein. The nucleic acid DNA transmits genetic information. The chromosomes

also bear the basic units of heredity called genes .

 

The genes determine the characteristics of the cells, and act as control

units in the metabolic activities of the cell. Genes therefore serve as code

units which determine most of the enzymatic and other biochemical activities

within the cell. It is through the genes that this basic metabolic data is

passed on from one generation of cells to the next. The cytoplasm

surrounding the nucleus of the cell contains a complex network of membranes

known as the endoplasmic reticulum . This reticulum is lined on its outer

surface by small particles called ribosomes . The ribosomes contain large

concentrations of a nucleic acid known as ribonucleic acid (RNA).

 

These ribosomes are directly concerned with protein synthesis. RNA also

occurs in the nucleus of the cell. It is now known that RNA is synthesized

in the nucleus of the cell and migrates to the cytoplasm. The DNA acts as a

template or pattern for the synthesis of RNA, which in turn acts as a

biochemical messenger between the DNA of the nucleus and the metabolic

machinery of the cytoplasm. Thus, RNA appears to exert a controlling

influence over the entire metabolic activities of the cell. Any alteration

in the DNA mechanism is going to affect the RNA messenger and thereby alter

the metabolic changes in the cell. In case of cancer, the regulatory

mechanism that governs cell division is obviously affected and the cells

begin to rapidly proliferate and gradually lose their differentiation.

 

There are numerous theories that have been proposed as to the cause of

cancer. It is now apparent that cancer may be caused by an almost limitless

variety of physical, chemical and biological agents. However, it is becoming

increasingly apparent that regardless of the precipitating factor, somewhere

along the progression of biochemical events, the basic DNA-RNA mechanism is

involved. If this vital genetic machinery is damaged, cancer may be the end

result. It would appear that if the cause of cancer is due to an alteration

of the normal metabolism of the cell, then the correction of the problem

would be by means of a Metabolic approach, which is basically the subject of

this web page.

 

Amygdalin ( Laetrile ) History and Actions

 

Amygdalin is a herbal constituent derived from the kernels of various fruits

of the Genus Prunus (synonym amygdalus) , which includes the plum, prune,

cherry, peach and apricot. It is among the most ancient herbal products used

against cancer. Apricot kernels have been in medical use since the days of

Pen T'sao (great Chinese Herbalist), in the year 2800 B.C., in ancient

China. Also, the great Persian master of pharmacy, medicine and natural

sciences, Avicenna (980-1037) recommended the use of apricot bitter almond

oil in the treatment of tumors of the spleen, uterus, stomach and liver.

Amygdalin is one of the first and best known cyanogenic glycosides. The

systematized study of amygdalin did not really begin until the first half of

the past century when crystalline amygdalin was isolated in 1830 by two

French chemists, Robiquet and Boutron. Now known as Prunus Amygdalus, of the

rose family Rosaceae, amygdalin is hence appropriately named after the

scientific name of the bitter almond. The chemical structure of amygdalin is

well established as laevo-D-mandelonitrile-B-D-glucoside-6-B-D-glucoside;

essentially, it is a diglucoside with a cyanide radical. Laetrile is a

decomposition product resulting from the hydrolysis of amygdalin. Neither

amygdalin nor laetrile contain free cyanide. Laetrile formula is

laevo-D-mandelonitrile-B-glucoronide. The term laetrile was first proposed

by Ernest T. Krebs, Jr. in 1949.

 

The word is derived from the contraction of the chemical term LAE

vo-mandeloni TRILE . Krebs also designated laetrile as vitamin B17 . Krebs

contended that amygdalin is essential to human health. The Amygdalin Therapy

The amygdalin (laetrile) therapy utilizes the cyanogenic glycoside

amygdalin, or one of it's byproducts, together with a broad-based

nutritional program Metabolic Therapy for the control of cancer. Krebs, Jr.

and his research group found that amygdalin has it's powerful cancer killer

capabilities because it contains cyanide that destroys cancer cells. Not all

cyanide compounds are poisonous, humans constantly eat produce with cyanide,

about 1,200 kinds of foods have it. Detoxification of cyanide can take place

in all tissues of the body, but principally in the liver. The dosage levels

and toxicity of amygdalin (laetrile) in laboratory animals and humans is

well established and documented. No evidence of acute or accumulative

toxicity was observed in any animals giving doses in excess of 100 times the

maximum intravenous dose usually given in humans.

 

These findings coincide with that mentioned by Otto Jacobsen in 1887,

Davidson in 1944 and Dr. Dean Burk ( National Cancer Institute) in 1968:

" Amygdalin is impressively nontoxic from the pharmacological point of view " ,

and " non-hydrolyzed amygdalin is less toxic than glucose " . The oral toxicity

of amygdalin was found to be 39 to 44 times greater than the intramuscular

route, and more toxic than intravenous route (parentenal route). Amygdalin

is less tolerable by oral administration because of the hydrolysis of

amygdalin by the gastric juices. On the other hand, amygdalin, in dosages of

20-40/mg/kg orally (for a 200 lb human this would translate to 16 - 500mg

laetrile/B17 tablets, daily), used in humans, is 10 to 20 times less than

the minimum toxic dosage in dogs. The biological half life of amygdalin is

only 80 minutes. Over 80% of the amygdalin administered is excreted from the

body in 4 hours. The usual metabolic approach to amygdalin (laetrile)

therapy is to provide the patient with adequate nutritional support, with

relatively nontoxic high doses of vitamins and minerals, and other active

natural substances.

Amygdalin (laetrile) has been administered in dosages of up to 70 grams

(70,000 miligrams-mg) per day in adult humans by combined oral and

parentenal routes without adverse effects.

 

Amygdalin's Action Mechanisms (Krebs Hypothesis)

 

The most widespread theory ( " cyanide theory " ) on the action of amygdalin was

propounded by Ernest Krebs, Jr. in the seventies. Krebs hypothesis: The

resulting end products of the hydrolysis of amygdalin are the hydrocyanic

acid (HCN) and benzaldehyde. In order to produce these products

B-glucuronidase is required. It has been demonstrated that this enzyme is

present in cancerous tissue, about 1,000 to 3,600 times higher than in

normal tissue. Rhodanase is an enzyme found in the liver cell and is known

to be concerned with the conversion of toxic hydrocyanic acid to

thiocyanate, a harmless substance. Rhodanase is part of the normal

detoxification process of the body. However, it was found that normal cells

contain a relatively high concentration of rhodanase and low concentration

of B-gluco-ronidase, whereas cancerous cells are high in available

B-glucoronidase and low in available rhodanase.

 

Thus, the normal cellular protective mechanism is decreased in tumor cells

and they become more sensitive to the effects of the cyanide ion. The HCN

would tend to depress the enzyme functions of the cancer cell and thereby

destroy it. Since normal cells contain large quantities of rhodanase and

relatively low quantities of available B-glucoronidase, the available

rhodanase would detoxify the cyanide ion (CN-), forming the non-toxic

thiocyanate. Then according to Ernest Krebs amygdalin's toxic effect is

against the cancerous cell and not the host.

 

The Effectiveness Of Amygdalin (laetrile) In Cancer

 

Ever since the days of Louis Pasteur (1822-1895) and Paul Ehrlich

(1854-1915), cancer victims have hoped for the " wonder vaccine " or the

" magic bullet " . Amygdalin (laetrile) does not come under the heading of

either of these dramatic therapies. There are a number of factors that enter

into the cancer treatment complex. The type of cancer involved is an

important factor. Some types of cancer tend to be more sensitive to

treatment than other. Amygdalin (laetrile) is not equally effective in all

types of cancers. Rubin (1977) found in their clinical investigations in

Israel that Amygdalin (laetrile) was most effective against Adenocarcinoma

and Hodgkin's disease, somewhat less effective in certain other of the

Sarcomas and Melanomas , and relatively poor results were achieved with the

Leukemia. Similar results have been obtained by other clinicians in the

United States and elsewhere. The best results with Amygdalin (laetrile)

therapy have been achieved with Lung, Prostate, Breast, Lymphomas, Liver and

Brain cancer. The chemical quality of the Amygdalin (laetrile) also has a

bearing on the clinical therapeutic results.

 

Only the laevo isomer of Amydalin (laetrile) has been found to be

therapeutically active. A high quality Amygdalin is now produced in Mexico

and some products are currently under investigation in the United States and

Germany . It is therefore of the utmost importance that quality products be

utilized. Failure to recognize this point can result in inadequate dosage

levels and false negative therapeutic results (Krible, 1912; Levi, et al,

1965; Rubin, 1978). Other factors relating directly to the administration of

Amygdalin (laetrile) concern the dosage. In the past, most physicians have

tended toward administering too low a dosage. Therefore the frequency of

administration, the route of administration, and the dosage are of the

utmost importance if adequate blood levels are to be maintained. In the

past, most errors of administration have been made on the side of too

little, rather than too much. However, it should be kept in mind that the

most effective routes are by parenteral injection (I.M or I.V.) and the

physician should not attempt to achieve the necessary dosage levels by the

oral route. Rubin (1978) reports administering 70gr. per day to each patient

with no ill effects. Another aspect that will have a bearing on the recovery

of a patient depends upon the degree of tissue damage caused by excessive

radiation and toxicity resulting from chemotherapy.

 

It is presently estimated in the United States, Mexico, and elsewhere, that

about 90% or more of the patients begin using Amygdalin (laetrile) only

after all other types of cancer therapies have failed. Most metabolic

physicians are of the opinion that if the patient were to begin Metabolic

Therapy earlier in the course of the disease, it would improve the patient's

chances of Cancer Control. The adequacy of liver functions is of the utmost

importance in cancer therapy. The liver has varied, intricate and extremely

complex metabolic functions. Among other things the liver is concerned with

fat, carbohydrate and protein metabolism.

 

The liver has a propensity for storing vitamins, especially A, D and B 12 ,

and Iron in the form of ferritin. The liver forms a large proportion of the

blood constituents: Fibrinogen, Prothrombin, Accelerator Globulin, Factor

VII, and other coagulation factors. The liver is involved in vitamin K

metabolism. The liver is concerned with the vascular storage and filtration

of blood, with about 1000ml of blood flowing from the portal vein through

the liver sinusoids each minute, and an additional 400ml flows into the

sinusoid from the hepatic artery. Thus when the liver or kidneys are damaged

due to a primary or metastatic malignancy, it may adversely affect the

entire metabolism of the body.

 

The studies conducted thus far on Amygdalin (laetrile) indicate that there

is no damage to the liver or kidney function. Much of the effort of

metabolic therapy is dedicated toward sustaining adequate liver and kidney

functions, and to attempt to minimize the detoxification load placed upon

them. It should be emphasized that Amygdalin (laetrile) therapy is most

effective when used in conjunction with a comprehensive METABOLIC approach.

Most physicians using this form of therapy provide adequate nutritional

support with the use of proper vitamin and mineral supplements. The patient

is placed on a complete vegetarian diet with a reduction of proteins, fats,

refined sugars, and processed foods. All tobacco, alcohol, caffeinated

drinks, and most toxic medications are eliminated. The patient is placed on

a high intake of select fruit juices, fresh fruits and vegetables. A program

of Detoxification is required. A minimum of 9gr of Amygdalin (laetrile) per

day is administered, largely by the parenteral route, but even higher levels

may be given if indicated. Patients that refuse to follow the general

Metabolic Program are discouraged from taking Amygdalin (laetrile) .

 

Alternative Forms Of Cancer Treatments

 

There are probably as many different forms of cancer therapy as there are

types of cancer. There are cancerous conditions which require surgery,

radiation, and/or chemotherapy. There are certain types of cancer, and

certain stages in the development of the cancer, that respond well to one or

more modalities. Significant success has been obtained in the treatment of

Hodgkin's disease, some leukemias, and certain other types of cancers. The

patient is advised to consult with a physician and seek the best medical

advice available. Most skin cancers can be readily treated with conventional

methods of therapy if instituted early enough. However, the most common type

of internal cancer is adenocarcinoma (involving the breast, intestinal

tract, lung, etc.). When an adenocarcinoma and certain of the sarcomas

undergo metastases, most conventional therapy is ineffective and the

prognosis of the patient is poor, using conventional therapies. The patient

is then left with the dilemma of Where do I go from here?

 

These cases should be encouraged to try Amygdalin (Laetrile) Therapy . If

the cancer victim is trying to decide how to proceed, whether to stay with

conventional therapy or the Life Without Cancer Amygdalin (laetrile) therapy

the following procedure is recommended: The patient should determine from

his physician the type of cancer with which he is afflicted and then visit

the Cancer Ward at any major medical center in the United States. Most

patients will find it very educational to visit a high-class conventional

Cancer Ward, subsidized by the National Cancer Institute and the American

Cancer Society , and check with the doctors, nurses and patients and see for

themselves just how many " terminal cancer victims " actually survive the

ordeal.

 

The fact that the wealthiest persons, most influential politicians,

brightest Hollywood stars, highly educated persons, and skilled orthodox

physicians are dying of metastatic malignancies should be suitable

commentary as to the efficacy of conventional therapy. The studies made in

1977, indicate that persons that combine Amygdalin (laetrile) with

conventional chemotherapy are able to tolerate higher doses of toxic

chemotherapeutic agents with far less side effects. Interestingly enough,

this synergism is characteristic of adaptogenic agents.

 

What Of The Future?

 

Here is the forecast based on the evidence currently on hand:

 

a) Clinical trials on Amygdalin (laetrile) therapy using good quality

Amygdalin will continue to be conducted in the proper manner.

 

b) Amygdalin (laetrile) will be legalized in the United States with or

without the cooperation of the FDA at some point in the future.

 

c) The atrocities now being committed in the name of orthodox medicine, the

suppression of life-giving scientific data, the needless loss of lives,

mutilation of bodies, and excessive suffering, all for the financial benefit

of a ruthlessly powerful medical cartel which is flagrantly in violation of

the antitrust laws of this government, will not continue to be tolerated by

the American people.

 

Ultimately, these criminals and their political lackeys will be brought to

trial and they will find themselves responsive to the American people. The

following is one of the greatest rights ever given to a people: " NO STATE

SHALL MAKE OR ENFORCE ANY LAW WHICH SHALL ABRIDGE THE PRIVILEGES OR

IMMUNITIES OF CITIZENS OF THE UNITED STATES: NOR SHALL ANY STATE DEPRIVE ANY

PERSON OF LIFE, LIBERTY, OR PROPERTY, WITHOUT DUE PROCESS OF LAW, NOR DENY

TO ANY PERSON WITHIN ITS JURISDICTION THE EQUAL PROTECTION OF THE LAWS " .

(from the 14th amendment of the constitution of the United States of

America. 1868)

 

_______________

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