Guest guest Posted February 21, 2007 Report Share Posted February 21, 2007 I think we may have the same problem - as I cannot specifically recall which forum I might have made the post in. Likely the post was on a different subject and made mention of a natural botanical or supplement that was also thought to be effective for Alzheimer's.I did a search on my computers for articles and documents that contained references to Alzheimer's and came up with about 80 different documents. As it turns out, I plan to put all of the Alzheimer's information I have together plus do some more research and write an article about Alzheimer's soon - a project that I have intended to do for quite awhile, but like many things has has to remain on the back burner for awhile.For now, I would say that the following message in Jon Barron's Baseline of Health Foundation newsletter is about as good as it gets: Alzheimer's and Dementia Bullets Jon Barron Well, it looks like Alzheimer's is set to become our next big medical terror. In the early 1900's it was infectious diseases. From 1950 to around 1975, it was heart disease; and then from the mid 70's to pretty much now, it's been cancer. But rising rapidly in our consciousness as it makes regular appearances on popular TV shows from Boston Legal to Grey's Anatomy, Alzheimer's looks ready to take its place as our new collective nightmare. So what is Alzheimer's? What do we know about it? What can we do about it? Before we begin, though, let's separate dementia and Alzheimer's. They are not the same thing. Dementia simply refers to a progressive decline in cognitive function beyond what might be expected from normal aging. Alzheimer's is only one possible cause. Strokes, for example, may damage parts of the brain thus leading to dementia. Then again, common prescription drugs such as sleep aids, anti-anxiety drugs, antidepressants, allergy drugs, and even cold remedies can cause dementia as a side effect. How prevalent is this particular problem? According to Mike Adams of NewsTarget.com, it represents the vast majority of people diagnosed with Alzheimer's. More traditional authorities, of course, say side effects from prescription drugs are responsible for only a minority of such dementia cases, but even according to these same conservative sources, such side effects may still represent 15-30% of all dementia diagnoses. In any event, it still leaves millions of people worldwide afflicted with true Alzheimer's disease. Alzheimer's, the statistics An estimated 4.5 million Americans have Alzheimer's disease. The number of Americans with Alzheimer's has more than doubled since 1980. Worldwide, it is estimated that there are currently 18 million people with Alzheimer's disease. This figure is projected to nearly double by 2025 to 34 million people and reach 52 million by 2050. The cost of Alzheimer's, in the United States alone, was estimated to be $67.3 billion in 1991, climbing to at least $100 billion based on 1994 data -- with projections of at least $160 billion a year by 2010. Alzheimer's, the facts Scientists do not yet fully understand what causes Alzheimer's. There probably is not one single cause, but several factors that affect each person differently. The greatest known risk factor for Alzheimer's is increasing age. Most individuals with the disease are 65 or older. The likelihood of developing Alzheimer's doubles about every five years after age 65. After age 85, the risk reaches nearly 50 percent. Risk genes increase the likelihood of developing the disease, but do not guarantee it will happen. Scientists have so far identified one Alzheimer risk gene called apoliprotein E-e4 (APOE-e4). They have also found rare genes that directly cause Alzheimer's in only a few hundred extended families worldwide. There appears to be a strong link between serious head injury and future risk of Alzheimer's. Modest head trauma, however, seems to produce no increased risk. Some of the strongest evidence links brain health to heart health. Your brain is nourished by one of your body's richest networks of blood vessels. Every heartbeat pumps about 20 to 25 percent of your blood to your head, where brain cells use at least 20 percent of the food and oxygen your blood carries. Reduce that flow, and you damage your brain. A study published in the Archives of Neurology linked sufferers of diabetes to a 65 percent higher risk of developing Alzheimer's disease. A more recent study puts the risk at almost double. New research indicates that inflammatory stress leading to metabolic changes in brain proteins may be a significant factor. And finally, there is the much debated aluminum connection. Much of the ambiguity may be because researchers are looking at the wrong culprit. There are indications that aluminum by itself may not be a significant trigger for Alzheimer's, but aluminum fluoride may be. Where does that leave us? So what do we know from all of these facts and figures, other than that we are afraid and that Alzheimer's is going to cost us a great deal of money? Actually, when you look at the data as the proverbial forest and not just as a series of isolated trees, quite a bit. There probably is not one single cause, but several factors that affect each person differently. That means that the search for "The Cure for Alzheimer's" is likely to be fruitless, in addition to being extremely expensive -- but with massive amounts of research money available, it will continue nonetheless. It's not primarily related to genetics. Rather it's related to deteriorating conditions connected with the aging process. Most of those conditions can be ameliorated, or even reversed, through the use of diet and lifestyle changes and the use of supplements. So what can we do? So, given what we've observed above, what can we do to improve our odds of being among the 50% unafflicted group at age 85? As turns out, quite a lot, and even better, nothing other than what you should already be doing to maintain optimum health. If you're following the Baseline of Health Program, you're already covered. For those of you not familiar with the Baseline of Health Program, you can download a free copy of Lessons from the Miracle Doctors at jonbarron.org. It lays out the whole program in detail. But in summary, as it applies to Alzheimer's: Heart health The connection of Alzheimer's with cardiovascular disease would appear to have two primary components: (1) reduced flow of oxygen and nutrients to the brain resulting from restricted arteries and (2) inflammation of areas of the brain caused by many of the same factors that cause inflammation of arterial tissue, which leads to the hardening of the arteries and the build up of arterial plaque. Obviously, dietary changes such as avoiding heavy consumption of saturated fats and transfatty acids make sense. Reduce consumption of high Omega-6 vegetables oils. Supplementation with Omega-3 fatty acids is obviously essential. For the best sources of Omega-3 fatty acids check out my blog entry. Reduce homocysteine levels by using a supplement that includes B12, folic acid, and TMG. Also, regular use of methylation supplements such as SAMe is useful. Inflammation Systemic inflammation is starting to emerge as one of the biggest risk factors you face. It is now implicated in everything from heart disease to cancer to Alzheimer's. Reducing that inflammation is not difficult. Again, Omega-3 fatty acids play a key role here. Supplement! A good systemic proteolytic enzyme formula can work wonders here. Diabetes The primary culprit when it comes to diabetes appears to be glycation. Glycation is the uncontrolled reaction of sugars with proteins. It's kind of like what happens to sugars when you heat them and they caramelize. In effect, glycation is what happens when excess sugars caramelize the proteins in your body. It's a major factor in the aging process -- and it's particularly devastating to diabetics. Thanks largely to the destructive effect of sugar and aldehydes, the protein in our bodies tends to undergo destructive changes as we age. This destruction is a prime factor, not only in the aging process itself, but also in the familiar signs of aging such as wrinkling skin, cataracts, and the destruction of our nervous system -- particularly our brains. Reducing consumption of high glycemic foods such as sugars and refined grains is step one. Reducing the impact of any high glycemic foods that you do eat and optimizing the metabolism of carbohydrates in general is step two. Reversing the damage caused by any of the sugars and alcohols that sneak through is step three. A formula comprised of L. carnosine, DMAE, and Acetyl-l-carnitine, can help reverse damage caused by beta amyloid plaque in the brain, a primary Alzheimer's suspect. I have seen such a formula produce dramatic improvements in as little as 24-72 hours. Other supplements that can help include CoQ10 and Gingko biloba. Heavy metals Not just aluminum and fluoride, but all heavy metals including lead can cause deterioration of brain function. Regular use of a good chelating formula makes a great deal of sense. Exercise And finally there's exercise, not just physical but also mental. Regular aerobic exercise improves oxygen flow to the brain. Even regular dancing has been shown to help. Weight bearing exercise can increase human growth hormone production by as much as 800%. Stretching exercise opens up circulation to every area of the body. Thinking exercises that challenge your mind make a difference. Playing bridge, chess, or a musical instrument all help. In fact, studies have shown that people who do 4 crossword puzzles a week have a 47% reduced risk of Alzheimer's. What do you think about that? # # # Misc Index of archived newsletters and reportsPremium versions of Jon's formulas are now available at www.baselinenutritionals.com For those of you who have already written reviews for Jon Barron's Lessons from the Miracle Doctors on the Amazon.com website, thanks for your support. For the rest of you, feel free to log on and write a review. Every good review helps. Thanks for your support. Sincerely, Kristen Barron Baseline of Health Foundation kanienkaha <kanienkahagen wrote: hello everyone. i am new to this group. i learned of it from a post on another site by the owner of this group. in that post you also mentioned a drug over in europe i believe thats used for alzheimer patients and that has anti-aging properties. what was this called? i can't remember the site i saw you talk on. maybe i need that drug eh? Mo Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 there is hope for me yet. it was on the unofficial WRH message board. and the name of the drug is Centrophenoxine. is there a reliable source of this? oleander soup , Tony Isaacs wrote: > > I think we may have the same problem - as I cannot specifically recall which forum I might have made the post in. Likely the post was on a different subject and made mention of a natural botanical or supplement that was also thought to be effective for Alzheimer's. > > I did a search on my computers for articles and documents that contained references to Alzheimer's and came up with about 80 different documents. As it turns out, I plan to put all of the Alzheimer's information I have together plus do some more research and write an article about Alzheimer's soon - a project that I have intended to do for quite awhile, but like many things has has to remain on the back burner for awhile. > > For now, I would say that the following message in Jon Barron's Baseline of Health Foundation newsletter is about as good as it gets: > > Alzheimer's and Dementia Bullets > Jon Barron Well, it looks like Alzheimer's is set to become our next big medical terror. In the early 1900's it was infectious diseases. From 1950 to around 1975, it was heart disease; and then from the mid 70's to pretty much now, it's been cancer. But rising rapidly in our consciousness as it makes regular appearances on popular TV shows from Boston Legal to Grey's Anatomy, Alzheimer's looks ready to take its place as our new collective nightmare. So what is Alzheimer's? What do we know about it? What can we do about it? > Before we begin, though, let's separate dementia and Alzheimer's. They are not the same thing. Dementia simply refers to a progressive decline in cognitive function beyond what might be expected from normal aging. Alzheimer's is only one possible cause. Strokes, for example, may damage parts of the brain thus leading to dementia. Then again, common prescription drugs such as sleep aids, anti- anxiety drugs, antidepressants, allergy drugs, and even cold remedies can cause dementia as a side effect. How prevalent is this particular problem? According to Mike Adams of NewsTarget.com, it represents the vast majority of people diagnosed with Alzheimer's. More traditional authorities, of course, say side effects from prescription drugs are responsible for only a minority of such dementia cases, but even according to these same conservative sources, such side effects may still represent 15-30% of all dementia diagnoses. > In any event, it still leaves millions of people worldwide afflicted with true Alzheimer's disease. > Alzheimer's, the statistics > An estimated 4.5 million Americans have Alzheimer's disease. The number of Americans with Alzheimer's has more than doubled since 1980. > Worldwide, it is estimated that there are currently 18 million people with Alzheimer's disease. This figure is projected to nearly double by 2025 to 34 million people and reach 52 million by 2050. > The cost of Alzheimer's, in the United States alone, was estimated to be $67.3 billion in 1991, > climbing to at least $100 billion based on 1994 data -- with projections of at least $160 billion a year by 2010. > Alzheimer's, the facts Scientists do not yet fully understand what causes Alzheimer's. There probably is not one single cause, but several factors that affect each person differently. > > The greatest known risk factor for Alzheimer's is increasing age. Most individuals with the disease are 65 or older. The likelihood of developing Alzheimer's doubles about every five years after age 65. After age 85, the risk reaches nearly 50 percent. > Risk genes increase the likelihood of developing the disease, but do not guarantee it will happen. Scientists have so far identified one Alzheimer risk gene called apoliprotein E-e4 (APOE- e4). They have also found rare genes that directly cause Alzheimer's in only a few hundred extended families worldwide. > There appears to be a strong link between serious head injury and future risk of Alzheimer's. Modest head trauma, however, seems to produce no increased risk. > Some of the strongest evidence links brain health to heart health. Your brain is nourished by one of your body's richest networks of blood vessels. Every heartbeat pumps about 20 to 25 percent of your blood to your head, where brain cells use at least 20 percent of the food and oxygen your blood carries. Reduce that flow, and you damage your brain. > A study published in the Archives of Neurology linked sufferers of diabetes to a 65 percent higher risk of developing Alzheimer's disease. A more recent study puts the risk at almost double. > New research indicates that inflammatory stress leading to metabolic changes in brain proteins may be a significant factor. > And finally, there is the much debated aluminum connection. Much of the ambiguity may be because researchers are looking at the wrong culprit. There are indications that aluminum by itself may not be a significant trigger for Alzheimer's, but aluminum fluoride may be. > Where does that leave us? So what do we know from all of these facts and figures, other than that we are afraid and that Alzheimer's is going to cost us a great deal of money? Actually, when you look at the data as the proverbial forest and not just as a series of isolated trees, quite a bit. > > There probably is not one single cause, but several factors that affect each person differently. That means that the search for " The Cure for Alzheimer's " is likely to be fruitless, in addition to being extremely expensive -- but with massive amounts of research money available, it will continue nonetheless. > It's not primarily related to genetics. Rather it's related to deteriorating conditions connected with the aging process. > Most of those conditions can be ameliorated, or even reversed, through the use of diet and lifestyle changes and the use of supplements. > So what can we do? So, given what we've observed above, what can we do to improve our odds of being among the 50% unafflicted group at age 85? As turns out, quite a lot, and even better, nothing other than what you should already be doing to maintain optimum health. If you're following the Baseline of Health Program, you're already covered. For those of you not familiar with the Baseline of Health Program, you can download a free copy of Lessons from the Miracle Doctors at jonbarron.org. It lays out the whole program in detail. But in summary, as it applies to Alzheimer's: > Heart health The connection of Alzheimer's with cardiovascular disease would appear to have two primary components: (1) reduced flow of oxygen and nutrients to the brain resulting from restricted arteries and (2) inflammation of areas of the brain caused by many of the same factors that cause inflammation of arterial tissue, which leads to the hardening of the arteries and the build up of arterial plaque. > > Obviously, dietary changes such as avoiding heavy consumption of saturated fats and transfatty acids make sense. > Reduce consumption of high Omega-6 vegetables oils. > Supplementation with Omega-3 fatty acids is obviously essential. For the best sources of Omega-3 fatty acids check out my blog entry. > Reduce homocysteine levels by using a supplement that includes B12, folic acid, and TMG. Also, regular use of methylation supplements such as SAMe is useful. > Inflammation Systemic inflammation is starting to emerge as one of the biggest risk factors you face. It is now implicated in everything from heart disease to cancer to Alzheimer's. Reducing that inflammation is not difficult. > > Again, Omega-3 fatty acids play a key role here. Supplement! > A good systemic proteolytic enzyme formula can work wonders here. > Diabetes The primary culprit when it comes to diabetes appears to be glycation. Glycation is the uncontrolled reaction of sugars with proteins. It's kind of like what happens to sugars when you heat them and they caramelize. In effect, glycation is what happens when excess sugars caramelize the proteins in your body. It's a major factor in the aging process -- and it's particularly devastating to diabetics. Thanks largely to the destructive effect of sugar and aldehydes, the protein in our bodies tends to undergo destructive changes as we age. This destruction is a prime factor, not only in the aging process itself, but also in the familiar signs of aging such as wrinkling skin, cataracts, and the destruction of our nervous system -- particularly our brains. > > Reducing consumption of high glycemic foods such as sugars and refined grains is step one. > Reducing the impact of any high glycemic foods that you do eat and optimizing the metabolism of carbohydrates in general is step two. > Reversing the damage caused by any of the sugars and alcohols that sneak through is step three. > A formula comprised of L. carnosine, DMAE, and Acetyl-l- carnitine, can help reverse damage caused by beta amyloid plaque in the brain, a primary Alzheimer's suspect. I have seen such a formula produce dramatic improvements in as little as 24-72 hours. > > Other supplements that can help include CoQ10 and Gingko biloba. > Heavy metals Not just aluminum and fluoride, but all heavy metals including lead can cause deterioration of brain function. > > Regular use of a good chelating formula makes a great deal of sense. > Exercise And finally there's exercise, not just physical but also mental. > > Regular aerobic exercise improves oxygen flow to the brain. Even regular dancing has been shown to help. > Weight bearing exercise can increase human growth hormone production by as much as 800%. > Stretching exercise opens up circulation to every area of the body. > Thinking exercises that challenge your mind make a difference. Playing bridge, chess, or a musical instrument all help. In fact, studies have shown that people who do 4 crossword puzzles a week have a 47% reduced risk of Alzheimer's. What do you think about that? > # # # > Misc > > Index of archived newsletters and reports > Premium versions of Jon's formulas are now available at www.baselinenutritionals.com > For those of you who have already written reviews for Jon Barron's Lessons from the Miracle Doctors on the Amazon.com website, thanks for your support. For the rest of you, feel free to log on and write a review. Every good review helps. Thanks for your support. > Sincerely, > Kristen Barron > Baseline of Health Foundation > kanienkaha <kanienkahagen wrote: hello everyone. i am new to this group. i learned of it from a post on > another site by the owner of this group. in that post you also > mentioned a drug over in europe i believe thats used for alzheimer > patients and that has anti-aging properties. what was this called? i > can't remember the site i saw you talk on. maybe i need that drug eh? > Mo > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 I am no fan of man made drugs and Centrophenoxine is no exception since half of it consists of a synthetic compound. I do not think that synthetic compounds are compatible with our natural bodies and that is likely the reason that fully 95% of the 15,000 FDA approved medications have side effects.Now, the other half of Centrophenoxine, DMAE, is a natural compound and I do like it for anti-aging and help with Alzheimer's dementia. It makes an excellent companion to Carnosine and L-Acetyl Carnitine.All three of those items may be obtained via the internet and at vitamin store outlets.Let me quote from Jon Barron's article on anti-aging:Alzheimer’s Carnosine has been proven to reduce or completely prevent cell damage caused by beta amyloid, one of the prime protein risk factors for Alzheimer’s. The presence of beta amyloid leads to damage of the nerves and arteries of the brain. Carnosine blocks and inactivates beta amyloid. In effect, it protects neural tissues against dementia. The key is that carnosine not only prevents damaging cross-links from forming in proteins, it eliminates cross-links that have previously formed in those proteins, thus restoring normal membrane function in cells. This is true not only in the brain, but in all the organs of our body – our skin included. Keep in mind that the damage you see in the skin is not just a cosmetic question. The Reversal of Age Carnosine levels in our body directly correlate with both the length and quality of our lives. And since carnosine levels decline with age, supplementation with carnosine represents one of the most powerful things you can do to hold back the ravages of old age. Results While it is true that many people who supplement with carnosine are going to notice everything from younger looking skin to more energy, the bottom line is that you really shouldn’t look for any short term benefits from carnosine supplementation. If any short-term benefits are noticed, you should consider them an added bonus. The reason you want to supplement with carnosine is for the long term, not for the short-term benefits that you may or may not notice. You supplement with carnosine to protect against the long-term ravages of aging. Using Carnosine Some experts recommend using only 50-100 mg of carnosine a day. Others say that if you don’t take 1,000-1,500 mg a day it won’t work because your body metabolizes the first 500 mg or so. The key here is that all of these experts are ignoring the simple fact, that different people need different amounts. For example: The older you get, the more you need. If you eat a mostly vegetarian diet, you need more. If you’re diabetic, or just have trouble with blood sugar, you need more. I think most people will do best on 500-750 mg a day. If you’re young and healthy and include meat in your diet, then 250 mg a day makes sense. As you get older, and if you’re starting to show signs of aging or glycation (such as cataracts), then you’d want to think of increasing the dosage up to 1,000 mg a day – maybe even as high as 1,500 mg a day. Safety In studies, carnosine has been proven safe in amounts as high as 70, 80, or even 100 grams a day, although a small number of people have noticed some minor muscle twitching at doses as small as 1,000 mg. The bottom line is use what you need, and you won’t have any problems – only benefits. Importance As I mentioned earlier, I don’t believe in magic bullets. Everything I’ve ever learned says that you’re only as strong as your weakest link. I still believe that improving your entire Baseline of Health is the key to good health and long life. But that said, I think that once you actually understand what carnosine does – once you understand the role it plays in preventing and potentially reversing all of the signs of old age in the body (and we’re talking about everything from wrinkled skin to cataracts to Alzheimer's) – heck, once you understand the role it plays in extending life itself – then you’re left with the unmistakable conclusion that supplementing with carnosine may represent one of the single best things you can do to help "turn back your biological clock." A Missing Link As important as carnosine is, there is a "gap" in its usefulness. It's called lipofuscin. Lipofuscin is the age pigment commonly found in aging brains and in other tissue such as the skin. By itself, it is not dangerous. It is merely a byproduct of harmful reactions that have already taken place. For example, one of the byproducts of free radical damage and protein/aldehyde damage (both conditions that carnosine addresses) is lipofuscin. When you supplement with carnosine, however, something different happens. The carnosine quickly binds with the aldehydes, preventing them from damaging the proteins. The byproduct of this reaction is lipofuscin. So once again you have inactive lipofuscin compounds, but this time as the result of PREVENTING protein damage. In a sense, with carnosine you trade protein damage for lipofuscin. As I said before, by itself, lipofuscin is not harmful. However, if enough of it accumulates over time (and this process is accelerated when you supplement with carnosine), it can interfere with proper cellular and organ functions. So the bottom line is that however it is produced (as a result of protein damage, or as the result of taking sacrificial carnosine to prevent protein damage), you want to get rid of it. DMAE By any definition, DMAE is the perfect companion to carnosine in an anti-aging formulation. First, it reinforces carnosine’s own anti-aging properties. Then, it provides a whole series of complementary benefits of its own. What Is DMAE? DMAE is short for (dimethylaminoethanol), a naturally-occurring nutrient that enhances acetylcholine (ACh) synthesis. Adequate levels of ACh are important for proper memory function. Normally found in small amounts in our brains, DMAE has been shown to remarkably enhance brain function when used as a supplement in clinical studies. It Reinforces Carnosine One of the prime actions of DMAE is that it flushes accumulated lipofuscin from your body – from the neurons in your brain, from your skin, and from all other organs. It also complements carnosine in that DMAE on its own has been shown to inhibit and reverse the Cross-Linking of proteins and extend lifespan. In Addition Many people have heard of the anti-aging results that Romanian scientist, Ana Aslin, achieved using something called GH3, or procaine. What most people do not know is that GH3 breaks down in the body to form DMAE (after first metabolizing into DEAE) and PABA. In other words, DMAE is the key active component in Ana Aslin’s anti-aging formula. Numerous scientific studies now show that DMAE can help: Increase Acetylcholine levels and RNA levels in the brain Stimulate mental activity Increase attention span Increase alertness Increase intelligence (especially in children) Improve learning and memory Increase energy levels Provide a mild, safe tonic effect Stimulate the central nervous system Relieve anxiety Elevate mood in general Alleviate behavioral problems and hyperactivity associated with Attention Deficit Disorder Increase motivation and reduce apathy in persons suffering from depression Induce sounder sleep Over time reduce the amount of sleep required by about 1 hour per night Intensify dreams tremendously. (Even more so when you take it along with a large dose of phosphatidyl choline -- a key component of lecithin) Cause dreams to become more lucid Increase willpower Decrease the incidence and severity of hangovers in people who consume excessive amounts of Alcohol And It’s Safe Clinical studies of DMAE have used up to 1,600 mg per day with no reports of side effects. In some cases, some people may experience slight headaches, muscle tension, or insomnia if they take too much too soon. These effects are easily eliminated if intake is reduced and then gradually increased. Although there is no direct connection, many manufacturers recommend that women who are pregnant or breast-feeding, anyone who suffers from convulsions, epilepsy, or seizure disorders, and people with manic-depressive illness should avoid using DMAE. This is probably more of a legal issue than a medical issue. Acetyl-L-Carnitine Like DMAE, acetyl-L-carnitine is a perfect complement to L-carnosine. Although your body can synthesize L-carnitine in the liver, it depends on outside sources (meat being a primary source) to fulfill its requirements. This can present a problem for vegetarians since L-carnitine performs several key functions in the human body. For one, it can improve the functioning of the immune system by enhancing the ability of macrophages to function as phagocytes. And it can improve the functioning of muscle tissue. In fact, it has been shown to increase running speed when given prior to exercise. It also plays a major factor in cellular energy production by shuttling fatty acids from the main cell body into the mitochondria (the cell’s energy factories) so that the fats can be oxidized for energy. Without carnitine, fatty acids cannot easily enter the mitochondria. There is, however, a specialized form of L-carnitine known as acetyl-L-carnitine (ALC) that is often deficient even in meat eaters and that performs virtually all of the same functions – but better. For example, in terms of cellular energy production, in addition to shuttling fatty acids into cell mitochondria, ALC provides acetyl groups from which Acetyl-Coenzyme A (a key metabolic intermediate) can be regenerated, thereby facilitating the transport of metabolic energy and boosting mitochondrial activity. But beyond that, the addition of the acetyl group makes ALC water soluble, which enables it not only to diffuse easily across the inner wall of the mitochondria but also to cross all cell membranes more easily. In other words, ALC reaches parts of the body where L-carnitine cannot go. In particular, ALC readily crosses the blood/brain barrier, where it provides a number of specialized neurological functions. For example, it can: Facilitate both the release and synthesis of acetylcholine, a key brain biochemical. Increase the brain's levels of choline acetylase. Enhance the release of dopamine and improve the binding of dopamine to dopamine receptors. Protect the neurons of the optic nerve and the occipital cortex of the brain. In addition, studies have shown that acetyl-L-carnitine can inhibit the deterioration in mental function associated with Alzheimer’s disease and slow its progression. Part of this is a result of its ability to shield neurons from the toxicity of beta amyloid protein. As a result: ALC improves alertness in Alzheimer’s patients. Improves attention span. And it increases short term memory. Through its action on dopamine (a chemical messenger used between nerve cells) and dopamine receptors, ALC seems to play a major role in preventing and/or minimizing the symptoms of Parkinson’s disease. ALC enhances the release of dopamine from dopaminergic neurons and improves the binding of dopamine to dopamine Receptors. ALC retards the decline in the number of dopamine receptors that occurs as part of the normal aging process and (more rapidly) with the onset of Parkinson's disease. In fact, many researchers believe that Parkinson's may be caused by a deficiency of dopamine. And ALC inhibits tremors. And acetyl-L-carnitine may even play a role in helping with MS. ALC inhibits (and possibly reverses) the degeneration of myelin sheaths But most of all, ALC just helps slow down the aging process of the brain. ALC retards the inevitable decline in the number of glucocorticoid receptors that occurs with aging. It retards the age-related deterioration of the hippocampus. It retards the inevitable decline in the number of nerve growth factor receptors that occurs as we age. It stimulates and maintains the growth of new neurons within the brain (both independently of Nerve Growth Factor (NGF) and as a result of preserving NGF) and helps to prevent the death of existing neurons. ALC protects the NMDA receptors in the brain from age-related decline. ALC inhibits the excessive release of adrenalin in response to stress and inhibits the depletion of luteinising hormone releasing hormone and testosterone that occurs as a result of excessive stress. And ALC enhances the function of cytochrome oxidase, an essential enzyme of the Electron Transport System. The mind boosting effect of acetyl-L-carnitine is often noticed within a few hours -- or even within an hour -- of supplementing. Most people report feeling mentally sharper, having more focus, and being more alert. Some find a mild mood enhancement. More specifically: ALC improves learning ability along with both short term and long term memory It improves mood by 53%. It both improves the quality of and reduces the need for sleep. It improves verbal fluency. And ALC improves hand eye coordination by some 300-400%. And yes, acetyl-L-carnitine helps flush lipofuscin from the body -- especially from the brain. Bottom Line Based on everything we know, supplementing with a combination of L-carnosine, DMAE, and Acetyl-L-carnitine is one of the simplest, most effective, and safest steps we can take to help turn back the clock and optimize our health. Live long, live healthy, live happy!Tony kanienkaha <kanienkahagen wrote: there is hope for me yet. it was on the unofficial WRH message board. and the name of the drug is Centrophenoxine. is there a reliable source of this? oleander soup , Tony Isaacs wrote: > > I think we may have the same problem - as I cannot specifically recall which forum I might have made the post in. Likely the post was on a different subject and made mention of a natural botanical or supplement that was also thought to be effective for Alzheimer's. > > I did a search on my computers for articles and documents that contained references to Alzheimer's and came up with about 80 different documents. As it turns out, I plan to put all of the Alzheimer's information I have together plus do some more research and write an article about Alzheimer's soon - a project that I have intended to do for quite awhile, but like many things has has to remain on the back burner for awhile. > > For now, I would say that the following message in Jon Barron's Baseline of Health Foundation newsletter is about as good as it gets: > > Alzheimer's and Dementia Bullets > Jon Barron Well, it looks like Alzheimer's is set to become our next big medical terror. In the early 1900's it was infectious diseases. From 1950 to around 1975, it was heart disease; and then from the mid 70's to pretty much now, it's been cancer. But rising rapidly in our consciousness as it makes regular appearances on popular TV shows from Boston Legal to Grey's Anatomy, Alzheimer's looks ready to take its place as our new collective nightmare. So what is Alzheimer's? What do we know about it? What can we do about it? > Before we begin, though, let's separate dementia and Alzheimer's. They are not the same thing. Dementia simply refers to a progressive decline in cognitive function beyond what might be expected from normal aging. Alzheimer's is only one possible cause. Strokes, for example, may damage parts of the brain thus leading to dementia. Then again, common prescription drugs such as sleep aids, anti- anxiety drugs, antidepressants, allergy drugs, and even cold remedies can cause dementia as a side effect. How prevalent is this particular problem? According to Mike Adams of NewsTarget.com, it represents the vast majority of people diagnosed with Alzheimer's. More traditional authorities, of course, say side effects from prescription drugs are responsible for only a minority of such dementia cases, but even according to these same conservative sources, such side effects may still represent 15-30% of all dementia diagnoses. > In any event, it still leaves millions of people worldwide afflicted with true Alzheimer's disease. > Alzheimer's, the statistics > An estimated 4.5 million Americans have Alzheimer's disease. The number of Americans with Alzheimer's has more than doubled since 1980. > Worldwide, it is estimated that there are currently 18 million people with Alzheimer's disease. This figure is projected to nearly double by 2025 to 34 million people and reach 52 million by 2050. > The cost of Alzheimer's, in the United States alone, was estimated to be $67.3 billion in 1991, > climbing to at least $100 billion based on 1994 data -- with projections of at least $160 billion a year by 2010. > Alzheimer's, the facts Scientists do not yet fully understand what causes Alzheimer's. There probably is not one single cause, but several factors that affect each person differently. > > The greatest known risk factor for Alzheimer's is increasing age. Most individuals with the disease are 65 or older. The likelihood of developing Alzheimer's doubles about every five years after age 65. After age 85, the risk reaches nearly 50 percent. > Risk genes increase the likelihood of developing the disease, but do not guarantee it will happen. Scientists have so far identified one Alzheimer risk gene called apoliprotein E-e4 (APOE- e4). They have also found rare genes that directly cause Alzheimer's in only a few hundred extended families worldwide. > There appears to be a strong link between serious head injury and future risk of Alzheimer's. Modest head trauma, however, seems to produce no increased risk. > Some of the strongest evidence links brain health to heart health. Your brain is nourished by one of your body's richest networks of blood vessels. Every heartbeat pumps about 20 to 25 percent of your blood to your head, where brain cells use at least 20 percent of the food and oxygen your blood carries. Reduce that flow, and you damage your brain. > A study published in the Archives of Neurology linked sufferers of diabetes to a 65 percent higher risk of developing Alzheimer's disease. A more recent study puts the risk at almost double. > New research indicates that inflammatory stress leading to metabolic changes in brain proteins may be a significant factor. > And finally, there is the much debated aluminum connection. Much of the ambiguity may be because researchers are looking at the wrong culprit. There are indications that aluminum by itself may not be a significant trigger for Alzheimer's, but aluminum fluoride may be. > Where does that leave us? So what do we know from all of these facts and figures, other than that we are afraid and that Alzheimer's is going to cost us a great deal of money? Actually, when you look at the data as the proverbial forest and not just as a series of isolated trees, quite a bit. > > There probably is not one single cause, but several factors that affect each person differently. That means that the search for "The Cure for Alzheimer's" is likely to be fruitless, in addition to being extremely expensive -- but with massive amounts of research money available, it will continue nonetheless. > It's not primarily related to genetics. Rather it's related to deteriorating conditions connected with the aging process. > Most of those conditions can be ameliorated, or even reversed, through the use of diet and lifestyle changes and the use of supplements. > So what can we do? So, given what we've observed above, what can we do to improve our odds of being among the 50% unafflicted group at age 85? As turns out, quite a lot, and even better, nothing other than what you should already be doing to maintain optimum health. If you're following the Baseline of Health Program, you're already covered. For those of you not familiar with the Baseline of Health Program, you can download a free copy of Lessons from the Miracle Doctors at jonbarron.org. It lays out the whole program in detail. But in summary, as it applies to Alzheimer's: > Heart health The connection of Alzheimer's with cardiovascular disease would appear to have two primary components: (1) reduced flow of oxygen and nutrients to the brain resulting from restricted arteries and (2) inflammation of areas of the brain caused by many of the same factors that cause inflammation of arterial tissue, which leads to the hardening of the arteries and the build up of arterial plaque. > > Obviously, dietary changes such as avoiding heavy consumption of saturated fats and transfatty acids make sense. > Reduce consumption of high Omega-6 vegetables oils. > Supplementation with Omega-3 fatty acids is obviously essential. For the best sources of Omega-3 fatty acids check out my blog entry. > Reduce homocysteine levels by using a supplement that includes B12, folic acid, and TMG. Also, regular use of methylation supplements such as SAMe is useful. > Inflammation Systemic inflammation is starting to emerge as one of the biggest risk factors you face. It is now implicated in everything from heart disease to cancer to Alzheimer's. Reducing that inflammation is not difficult. > > Again, Omega-3 fatty acids play a key role here. Supplement! > A good systemic proteolytic enzyme formula can work wonders here. > Diabetes The primary culprit when it comes to diabetes appears to be glycation. Glycation is the uncontrolled reaction of sugars with proteins. It's kind of like what happens to sugars when you heat them and they caramelize. In effect, glycation is what happens when excess sugars caramelize the proteins in your body. It's a major factor in the aging process -- and it's particularly devastating to diabetics. Thanks largely to the destructive effect of sugar and aldehydes, the protein in our bodies tends to undergo destructive changes as we age. This destruction is a prime factor, not only in the aging process itself, but also in the familiar signs of aging such as wrinkling skin, cataracts, and the destruction of our nervous system -- particularly our brains. > > Reducing consumption of high glycemic foods such as sugars and refined grains is step one. > Reducing the impact of any high glycemic foods that you do eat and optimizing the metabolism of carbohydrates in general is step two. > Reversing the damage caused by any of the sugars and alcohols that sneak through is step three. > A formula comprised of L. carnosine, DMAE, and Acetyl-l- carnitine, can help reverse damage caused by beta amyloid plaque in the brain, a primary Alzheimer's suspect. I have seen such a formula produce dramatic improvements in as little as 24-72 hours. > > Other supplements that can help include CoQ10 and Gingko biloba. > Heavy metals Not just aluminum and fluoride, but all heavy metals including lead can cause deterioration of brain function. > > Regular use of a good chelating formula makes a great deal of sense. > Exercise And finally there's exercise, not just physical but also mental. > > Regular aerobic exercise improves oxygen flow to the brain. Even regular dancing has been shown to help. > Weight bearing exercise can increase human growth hormone production by as much as 800%. > Stretching exercise opens up circulation to every area of the body. > Thinking exercises that challenge your mind make a difference. Playing bridge, chess, or a musical instrument all help. In fact, studies have shown that people who do 4 crossword puzzles a week have a 47% reduced risk of Alzheimer's. What do you think about that? > # # # > Misc > > Index of archived newsletters and reports > Premium versions of Jon's formulas are now available at www.baselinenutritionals.com > For those of you who have already written reviews for Jon Barron's Lessons from the Miracle Doctors on the Amazon.com website, thanks for your support. For the rest of you, feel free to log on and write a review. Every good review helps. Thanks for your support. > Sincerely, > Kristen Barron > Baseline of Health Foundation > kanienkaha <kanienkahagen wrote: hello everyone. i am new to this group. i learned of it from a post on > another site by the owner of this group. in that post you also > mentioned a drug over in europe i believe thats used for alzheimer > patients and that has anti-aging properties. what was this called? i > can't remember the site i saw you talk on. maybe i need that drug eh? > Mo > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2007 Report Share Posted February 23, 2007 nie:wen for the information. oleander soup , Tony Isaacs wrote: > > I am no fan of man made drugs and Centrophenoxine is no exception since half of it consists of a synthetic compound. I do not think that synthetic compounds are compatible with our natural bodies and that is likely the reason that fully 95% of the 15,000 FDA approved medications have side effects. > > Now, the other half of Centrophenoxine, DMAE, is a natural compound and I do like it for anti-aging and help with Alzheimer's dementia. It makes an excellent companion to Carnosine and L-Acetyl Carnitine. > > All three of those items may be obtained via the internet and at vitamin store outlets. > > Let me quote from Jon Barron's article on anti-aging: > > Alzheimer's Carnosine has been proven to reduce or completely prevent cell damage caused by beta amyloid, one of the prime protein risk factors for Alzheimer's. The presence of beta amyloid leads to damage of the nerves and arteries of the brain. Carnosine blocks and inactivates beta amyloid. In effect, it protects neural tissues against dementia. The key is that carnosine not only prevents damaging cross-links from forming in proteins, it eliminates cross- links that have previously formed in those proteins, thus restoring normal membrane function in cells. This is true not only in the brain, but in all the organs of our body – our skin included. Keep in mind that the damage you see in the skin is not just a cosmetic question. > > The Reversal of Age Carnosine levels in our body directly correlate with both the length and quality of our lives. And since carnosine levels decline with age, supplementation with carnosine represents one of the most powerful things you can do to hold back the ravages of old age. > > Results While it is true that many people who supplement with carnosine are going to notice everything from younger looking skin to more energy, the bottom line is that you really shouldn't look for any short term benefits from carnosine supplementation. If any short-term benefits are noticed, you should consider them an added bonus. > The reason you want to supplement with carnosine is for the long term, not for the short-term benefits that you may or may not notice. You supplement with carnosine to protect against the long- term ravages of aging. > > Using Carnosine Some experts recommend using only 50-100 mg of carnosine a day. Others say that if you don't take 1,000-1,500 mg a day it won't work because your body metabolizes the first 500 mg or so. > > The key here is that all of these experts are ignoring the simple fact, that different people need different amounts. For example: > > The older you get, the more you need. > If you eat a mostly vegetarian diet, you need more. > If you're diabetic, or just have trouble with blood sugar, you need more. > I think most people will do best on 500-750 mg a day. > > If you're young and healthy and include meat in your diet, then 250 mg a day makes sense. As you get older, and if you're starting to show signs of aging or glycation (such as cataracts), then you'd want to think of increasing the dosage up to 1,000 mg a day – maybe even as high as 1,500 mg a day. > > Safety > > In studies, carnosine has been proven safe in amounts as high as 70, 80, or even 100 grams a day, although a small number of people have noticed some minor muscle twitching at doses as small as 1,000 mg. The bottom line is use what you need, and you won't have any problems – only benefits. > > Importance > > As I mentioned earlier, I don't believe in magic bullets. Everything I've ever learned says that you're only as strong as your weakest link. I still believe that improving your entire Baseline of Health is the key to good health and long life. > But that said, I think that once you actually understand what carnosine does – once you understand the role it plays in preventing and potentially reversing all of the signs of old age in the body (and we're talking about everything from wrinkled skin to cataracts to Alzheimer's) – heck, once you understand the role it plays in extending life itself – then you're left with the unmistakable conclusion that supplementing with carnosine may represent one of the single best things you can do to help " turn back your biological clock. " > > A Missing Link As important as carnosine is, there is a " gap " in its usefulness. It's called lipofuscin. > > Lipofuscin is the age pigment commonly found in aging brains and in other tissue such as the skin. By itself, it is not dangerous. It is merely a byproduct of harmful reactions that have already taken place. For example, one of the byproducts of free radical damage and protein/aldehyde damage (both conditions that carnosine addresses) is lipofuscin. > > When you supplement with carnosine, however, something different happens. The carnosine quickly binds with the aldehydes, preventing them from damaging the proteins. The byproduct of this reaction is lipofuscin. So once again you have inactive lipofuscin compounds, but this time as the result of PREVENTING protein damage. In a sense, with carnosine you trade protein damage for lipofuscin. > > As I said before, by itself, lipofuscin is not harmful. However, if enough of it accumulates over time (and this process is accelerated when you supplement with carnosine), it can interfere with proper cellular and organ functions. So the bottom line is that however it is produced (as a result of protein damage, or as the result of taking sacrificial carnosine to prevent protein damage), you want to get rid of it. > > DMAE By any definition, DMAE is the perfect companion to carnosine in an anti-aging formulation. First, it reinforces carnosine's own anti-aging properties. Then, it provides a whole series of complementary benefits of its own. > > What Is DMAE? > DMAE is short for (dimethylaminoethanol), a naturally-occurring nutrient that enhances acetylcholine (ACh) synthesis. Adequate levels of ACh are important for proper memory function. Normally found in small amounts in our brains, DMAE has been shown to remarkably enhance brain function when used as a supplement in clinical studies. > > It Reinforces Carnosine > One of the prime actions of DMAE is that it flushes accumulated lipofuscin from your body – from the neurons in your brain, from your skin, and from all other organs. It also complements carnosine in that DMAE on its own has been shown to inhibit and reverse the Cross-Linking of proteins and extend lifespan. > In Addition Many people have heard of the anti-aging results that Romanian scientist, Ana Aslin, achieved using something called GH3, or procaine. What most people do not know is that GH3 breaks down in the body to form DMAE (after first metabolizing into DEAE) and PABA. In other words, DMAE is the key active component in Ana Aslin's anti-aging formula. > Numerous scientific studies now show that DMAE can help: > > Increase Acetylcholine levels and RNA levels in the brain > Stimulate mental activity > Increase attention span > Increase alertness > Increase intelligence (especially in children) > Improve learning and memory > Increase energy levels > Provide a mild, safe tonic effect > Stimulate the central nervous system > Relieve anxiety > Elevate mood in general > Alleviate behavioral problems and hyperactivity associated with Attention Deficit Disorder > Increase motivation and reduce apathy in persons suffering from depression > Induce sounder sleep > Over time reduce the amount of sleep required by about 1 hour per night > Intensify dreams tremendously. (Even more so when you take it along with a large dose of phosphatidyl choline -- a key component of lecithin) > Cause dreams to become more lucid > Increase willpower > Decrease the incidence and severity of hangovers in people who consume excessive amounts of Alcohol > And It's Safe > Clinical studies of DMAE have used up to 1,600 mg per day with no reports of side effects. In some cases, some people may experience slight headaches, muscle tension, or insomnia if they take too much too soon. > These effects are easily eliminated if intake is reduced and then gradually increased. Although there is no direct connection, many manufacturers recommend that women who are pregnant or breast- feeding, anyone who suffers from convulsions, epilepsy, or seizure disorders, and people with manic-depressive illness should avoid using DMAE. > This is probably more of a legal issue than a medical issue. > > Acetyl-L-Carnitine Like DMAE, acetyl-L-carnitine is a perfect complement to L-carnosine. > Although your body can synthesize L-carnitine in the liver, it depends on outside sources (meat being a primary source) to fulfill its requirements. This can present a problem for vegetarians since L- carnitine performs several key functions in the human body. For one, it can improve the functioning of the immune system by enhancing the ability of macrophages to function as phagocytes. And it can improve the functioning of muscle tissue. In fact, it has been shown to increase running speed when given prior to exercise. It also plays a major factor in cellular energy production by shuttling fatty acids from the main cell body into the mitochondria (the cell's energy factories) so that the fats can be oxidized for energy. Without carnitine, fatty acids cannot easily enter the mitochondria. > > There is, however, a specialized form of L-carnitine known as acetyl-L-carnitine (ALC) that is often deficient even in meat eaters and that performs virtually all of the same functions – but better. For example, in terms of cellular energy production, in addition to shuttling fatty acids into cell mitochondria, ALC provides acetyl groups from which Acetyl-Coenzyme A (a key metabolic intermediate) can be regenerated, thereby facilitating the transport of metabolic energy and boosting mitochondrial activity. But beyond that, the addition of the acetyl group makes ALC water soluble, which enables it not only to diffuse easily across the inner wall of the mitochondria but also to cross all cell membranes more easily. In other words, ALC reaches parts of the body where L-carnitine cannot go. In particular, ALC readily crosses the blood/brain barrier, where it provides a number of specialized neurological functions. For example, it can: > > Facilitate both the release and synthesis of acetylcholine, a key brain biochemical. > Increase the brain's levels of choline acetylase. > Enhance the release of dopamine and improve the binding of dopamine to dopamine receptors. > Protect the neurons of the optic nerve and the occipital cortex of the brain. > In addition, studies have shown that acetyl-L-carnitine can inhibit the deterioration in mental function associated with Alzheimer's disease and slow its progression. Part of this is a result of its ability to shield neurons from the toxicity of beta amyloid protein. As a result: > > ALC improves alertness in Alzheimer's patients. > Improves attention span. > And it increases short term memory. > Through its action on dopamine (a chemical messenger used between nerve cells) and dopamine receptors, ALC seems to play a major role in preventing and/or minimizing the symptoms of Parkinson's disease. > > ALC enhances the release of dopamine from dopaminergic neurons and improves the binding of dopamine to dopamine Receptors. > ALC retards the decline in the number of dopamine receptors that occurs as part of the normal aging process and (more rapidly) with the onset of Parkinson's disease. In fact, many researchers believe that Parkinson's may be caused by a deficiency of dopamine. > And ALC inhibits tremors. > And acetyl-L-carnitine may even play a role in helping with MS. > > ALC inhibits (and possibly reverses) the degeneration of myelin sheaths > But most of all, ALC just helps slow down the aging process of the brain. > > ALC retards the inevitable decline in the number of glucocorticoid receptors that occurs with aging. > It retards the age-related deterioration of the hippocampus. > It retards the inevitable decline in the number of nerve growth factor receptors that occurs as we age. > It stimulates and maintains the growth of new neurons within the brain (both independently of Nerve Growth Factor (NGF) and as a result of preserving NGF) and helps to prevent the death of existing neurons. > ALC protects the NMDA receptors in the brain from age- related decline. > ALC inhibits the excessive release of adrenalin in response to stress and inhibits the depletion of luteinising hormone releasing hormone and testosterone that occurs as a result of excessive stress. > And ALC enhances the function of cytochrome oxidase, an essential enzyme of the Electron Transport System. > The mind boosting effect of acetyl-L-carnitine is often noticed within a few hours -- or even within an hour -- of supplementing. Most people report feeling mentally sharper, having more focus, and being more alert. Some find a mild mood enhancement. More specifically: > > ALC improves learning ability along with both short term and long term memory > It improves mood by 53%. > It both improves the quality of and reduces the need for sleep. > It improves verbal fluency. > And ALC improves hand eye coordination by some 300-400%. > And yes, acetyl-L-carnitine helps flush lipofuscin from the body -- especially from the brain. > > Bottom Line Based on everything we know, supplementing with a combination of L-carnosine, DMAE, and Acetyl-L-carnitine is one of the simplest, most effective, and safest steps we can take to help turn back the clock and optimize our health. > > Live long, live healthy, live happy! > > > > > kanienkaha <kanienkahagen wrote: there is hope for me yet. it was on the unofficial WRH message > board. and the name of the drug is Centrophenoxine. is there a > reliable source of this? > > oleander soup , Tony Isaacs @> > wrote: > > > > I think we may have the same problem - as I cannot specifically > recall which forum I might have made the post in. Likely the post > was on a different subject and made mention of a natural botanical > or supplement that was also thought to be effective for Alzheimer's. > > > > I did a search on my computers for articles and documents that > contained references to Alzheimer's and came up with about 80 > different documents. As it turns out, I plan to put all of the > Alzheimer's information I have together plus do some more research > and write an article about Alzheimer's soon - a project that I have > intended to do for quite awhile, but like many things has has to > remain on the back burner for awhile. > > > > For now, I would say that the following message in Jon Barron's > Baseline of Health Foundation newsletter is about as good as it gets: > > > > Alzheimer's and Dementia Bullets > > Jon Barron Well, it looks like Alzheimer's is set to become > our next big medical terror. In the early 1900's it was infectious > diseases. From 1950 to around 1975, it was heart disease; and then > from the mid 70's to pretty much now, it's been cancer. But rising > rapidly in our consciousness as it makes regular appearances on > popular TV shows from Boston Legal to Grey's Anatomy, Alzheimer's > looks ready to take its place as our new collective nightmare. So > what is Alzheimer's? What do we know about it? What can we do about > it? > > Before we begin, though, let's separate dementia and Alzheimer's. > They are not the same thing. Dementia simply refers to a progressive > decline in cognitive function beyond what might be expected from > normal aging. Alzheimer's is only one possible cause. Strokes, for > example, may damage parts of the brain thus leading to dementia. > Then again, common prescription drugs such as sleep aids, anti- > anxiety drugs, antidepressants, allergy drugs, and even cold > remedies can cause dementia as a side effect. How prevalent is this > particular problem? According to Mike Adams of NewsTarget.com, it > represents the vast majority of people diagnosed with Alzheimer's. > More traditional authorities, of course, say side effects from > prescription drugs are responsible for only a minority of such > dementia cases, but even according to these same conservative > sources, such side effects may still represent 15-30% of all > dementia diagnoses. > > In any event, it still leaves millions of people worldwide > afflicted with true Alzheimer's disease. > > Alzheimer's, the statistics > > An estimated 4.5 million Americans have Alzheimer's disease. > The number of Americans with Alzheimer's has more than doubled since > 1980. > > Worldwide, it is estimated that there are currently 18 million > people with Alzheimer's disease. This figure is projected to nearly > double by 2025 to 34 million people and reach 52 million by 2050. > > The cost of Alzheimer's, in the United States alone, was > estimated to be $67.3 billion in 1991, > > climbing to at least $100 billion based on 1994 data -- > with projections of at least $160 billion a year by 2010. > > Alzheimer's, the facts Scientists do not yet fully understand > what causes Alzheimer's. There probably is not one single cause, but > several factors that affect each person differently. > > > > The greatest known risk factor for Alzheimer's is increasing > age. Most individuals with the disease are 65 or older. The > likelihood of developing Alzheimer's doubles about every five years > after age 65. After age 85, the risk reaches nearly 50 percent. > > Risk genes increase the likelihood of developing the disease, > but do not guarantee it will happen. Scientists have so far > identified one Alzheimer risk gene called apoliprotein E-e4 (APOE- > e4). They have also found rare genes that directly cause Alzheimer's > in only a few hundred extended families worldwide. > > There appears to be a strong link between serious head injury > and future risk of Alzheimer's. Modest head trauma, however, seems > to produce no increased risk. > > Some of the strongest evidence links brain health to heart > health. Your brain is nourished by one of your body's richest > networks of blood vessels. Every heartbeat pumps about 20 to 25 > percent of your blood to your head, where brain cells use at least > 20 percent of the food and oxygen your blood carries. Reduce that > flow, and you damage your brain. > > A study published in the Archives of Neurology linked > sufferers of diabetes to a 65 percent higher risk of developing > Alzheimer's disease. A more recent study puts the risk at almost > double. > > New research indicates that inflammatory stress leading to > metabolic changes in brain proteins may be a significant factor. > > And finally, there is the much debated aluminum connection. > Much of the ambiguity may be because researchers are looking at the > wrong culprit. There are indications that aluminum by itself may not > be a significant trigger for Alzheimer's, but aluminum fluoride may > be. > > Where does that leave us? So what do we know from all of these > facts and figures, other than that we are afraid and that > Alzheimer's is going to cost us a great deal of money? Actually, > when you look at the data as the proverbial forest and not just as a > series of isolated trees, quite a bit. > > > > There probably is not one single cause, but several factors > that affect each person differently. That means that the search > for " The Cure for Alzheimer's " is likely to be fruitless, in > addition to being extremely expensive -- but with massive amounts of > research money available, it will continue nonetheless. > > It's not primarily related to genetics. Rather it's related to > deteriorating conditions connected with the aging process. > > Most of those conditions can be ameliorated, or even reversed, > through the use of diet and lifestyle changes and the use of > supplements. > > So what can we do? So, given what we've observed above, what > can we do to improve our odds of being among the 50% unafflicted > group at age 85? As turns out, quite a lot, and even better, nothing > other than what you should already be doing to maintain optimum > health. If you're following the Baseline of Health Program, you're > already covered. For those of you not familiar with the Baseline of > Health Program, you can download a free copy of Lessons from the > Miracle Doctors at jonbarron.org. It lays out the whole program in > detail. But in summary, as it applies to Alzheimer's: > > Heart health The connection of Alzheimer's with cardiovascular > disease would appear to have two primary components: (1) reduced > flow of oxygen and nutrients to the brain resulting from restricted > arteries and (2) inflammation of areas of the brain caused by many > of the same factors that cause inflammation of arterial tissue, > which leads to the hardening of the arteries and the build up of > arterial plaque. > > > > Obviously, dietary changes such as avoiding heavy consumption > of saturated fats and transfatty acids make sense. > > Reduce consumption of high Omega-6 vegetables oils. > > Supplementation with Omega-3 fatty acids is obviously > essential. For the best sources of Omega-3 fatty acids check out my > blog entry. > > Reduce homocysteine levels by using a supplement that includes > B12, folic acid, and TMG. Also, regular use of methylation > supplements such as SAMe is useful. > > Inflammation Systemic inflammation is starting to emerge as one > of the biggest risk factors you face. It is now implicated in > everything from heart disease to cancer to Alzheimer's. Reducing > that inflammation is not difficult. > > > > Again, Omega-3 fatty acids play a key role here. Supplement! > > A good systemic proteolytic enzyme formula can work wonders > here. > > Diabetes The primary culprit when it comes to diabetes appears > to be glycation. Glycation is the uncontrolled reaction of sugars > with proteins. It's kind of like what happens to sugars when you > heat them and they caramelize. In effect, glycation is what happens > when excess sugars caramelize the proteins in your body. It's a > major factor in the aging process -- and it's particularly > devastating to diabetics. Thanks largely to the destructive effect > of sugar and aldehydes, the protein in our bodies tends to undergo > destructive changes as we age. This destruction is a prime factor, > not only in the aging process itself, but also in the familiar signs > of aging such as wrinkling skin, cataracts, and the destruction of > our nervous system -- particularly our brains. > > > > Reducing consumption of high glycemic foods such as sugars and > refined grains is step one. > > Reducing the impact of any high glycemic foods that you do eat > and optimizing the metabolism of carbohydrates in general is step > two. > > Reversing the damage caused by any of the sugars and alcohols > that sneak through is step three. > > A formula comprised of L. carnosine, DMAE, and Acetyl-l- > carnitine, can help reverse damage caused by beta amyloid plaque in > the brain, a primary Alzheimer's suspect. I have seen such a formula > produce dramatic improvements in as little as 24-72 hours. > > > > Other supplements that can help include CoQ10 and Gingko > biloba. > > Heavy metals Not just aluminum and fluoride, but all heavy > metals including lead can cause deterioration of brain function. > > > > Regular use of a good chelating formula makes a great deal of > sense. > > Exercise And finally there's exercise, not just physical but > also mental. > > > > Regular aerobic exercise improves oxygen flow to the brain. > Even regular dancing has been shown to help. > > Weight bearing exercise can increase human growth hormone > production by as much as 800%. > > Stretching exercise opens up circulation to every area of the > body. > > Thinking exercises that challenge your mind make a difference. > Playing bridge, chess, or a musical instrument all help. In fact, > studies have shown that people who do 4 crossword puzzles a week > have a 47% reduced risk of Alzheimer's. What do you think about that? > > # # # > > Misc > > > > Index of archived newsletters and reports > > Premium versions of Jon's formulas are now available at > www.baselinenutritionals.com > > For those of you who have already written reviews for Jon > Barron's Lessons from the Miracle Doctors on the Amazon.com website, > thanks for your support. For the rest of you, feel free to log on > and write a review. Every good review helps. Thanks for your > support. > > Sincerely, > > Kristen Barron > > Baseline of Health Foundation > > kanienkaha <kanienkahagen@> > wrote: hello everyone. i am new to > this group. i learned of it from a post on > > another site by the owner of this group. in that post you also > > mentioned a drug over in europe i believe thats used for > alzheimer > > patients and that has anti-aging properties. what was this > called? i > > can't remember the site i saw you talk on. maybe i need that drug > eh? > > Mo > > > Quote Link to comment Share on other sites More sharing options...
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