Prempro and Premarin Background and lawsuit #2

July 12, 2005

Prempro and Premarin BackgroundHormone Replace Therapy (HRT)

Under the guidance of the federal government, the National Heart, Lung and Blood Institute (NHLBI) launched a study to determine the long term effects of Prempro, a hormone replacement therapy drug. The study, originally planned to last eight years, was abruptly halted after five years when researchers determined the side effects were so severe they could not continue to give patients the drug.

The NHLBI study consisted of more than 16,000 women between the ages of 50 to 79. On May 31, 2002, the Data and Safety Monitoring Board made the decision to terminate the clinical trial. The board was alarmed at increases in heart problems and breast cancer among those women who were given Prempro.

According to the NHLBI, women who were given Prempro were more likely to develop serious problems compared to those in the placebo group.

26% increase in breast cancer

41% increase in strokes

100% increase in blood clots

22% increase in incidents of cardiovascular disease

Additional side effects associated with Prempro include ovarian cancer, lupus and gall bladder cancer. A study released in May 2003 by the AMA also noted increased risk of Alzheimer's disease and other forms of dementia.

We have compiled more detailed information on the dangerous Prempro side effects. We encourage you to explore both the prempro side effects and prempro news pages.

For free answers to your questions about Prempro and Premarin, just call us toll-free or submit this online contact form.