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Antioxidants may reduce urinary stones

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http://www.swansonvitamins.com/include/newsletter/emailRU_043004/RUa1_043004.htm\

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Antioxidants may reduce urinary stones risk

 

 

Researchers at the University of Madras in India believe that the antioxidants

vitamin E and selenium may help protect against hyperoxaluria.

 

Hyperoxaluria means there is excessive urinary oxalate in the body.

Hyperoxaluria is commonly found in patients with calcium oxalate kidney stones.

Oxalate is an organic acid and when it combines with calcium it produces an

insoluble product called calcium oxalate, the most common chemical compound

found in kidney stones. Urinary oxalate is the single strongest chemical

promoter of kidney stone formation.

 

Rats used in the study were lithogenic. That means they were secreting stony

deposits. Scientists discovered that the levels of lipid peroxidation and the

activities of oxalate-forming enzymes in the lithogenic rats were high. They

also found that the level and activity of antioxidants were decreased. The

urinary excretion of both oxalate and calcium was significantly elevated.

 

Supplementation with vitamin E and selenium decreased the levels of lipid

peroxides and the activities of oxalate-forming enzymes. Supplementation also

supported a healthy increase in antioxidant activity and the urinary excretion

of oxalate and calcium was normalized.

 

Journal of Nutritional Biochemistry 14(6):306-313, 2003

 

 

 

 

 

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