Guest guest Posted April 29, 2004 Report Share Posted April 29, 2004 http://www.swansonvitamins.com/include/newsletter/emailRU_043004/RUa1_043004.htm\ l Antioxidants may reduce urinary stones risk Researchers at the University of Madras in India believe that the antioxidants vitamin E and selenium may help protect against hyperoxaluria. Hyperoxaluria means there is excessive urinary oxalate in the body. Hyperoxaluria is commonly found in patients with calcium oxalate kidney stones. Oxalate is an organic acid and when it combines with calcium it produces an insoluble product called calcium oxalate, the most common chemical compound found in kidney stones. Urinary oxalate is the single strongest chemical promoter of kidney stone formation. Rats used in the study were lithogenic. That means they were secreting stony deposits. Scientists discovered that the levels of lipid peroxidation and the activities of oxalate-forming enzymes in the lithogenic rats were high. They also found that the level and activity of antioxidants were decreased. The urinary excretion of both oxalate and calcium was significantly elevated. Supplementation with vitamin E and selenium decreased the levels of lipid peroxides and the activities of oxalate-forming enzymes. Supplementation also supported a healthy increase in antioxidant activity and the urinary excretion of oxalate and calcium was normalized. Journal of Nutritional Biochemistry 14(6):306-313, 2003 Win a $20,000 Career Makeover at HotJobs Quote Link to comment Share on other sites More sharing options...
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