Growth Promoters in Beef have Estrogenic effects on Cancer Cells

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Growth Promoters in Beef have Estrogenic effects on Cancer Cells

JoAnn Guest

Oct 11, 2004 21:07 PDT

 

Growth Promoters in Beef have Estrogenic effects on Cancer Cells

 

Residual amounts of the growth promoter Zeranol, used in beef cattle

have an estrogenic effect on the growth of normal and cancerous

breast cells in humans, Ohio researchers reported here at the " Era

of Hope " Department of Defense Breast Cancer Research Program

Meeting.

 

Dr. Young C. Lin, of the Comprehensive Cancer Center at Ohio State

University, in Columbus, tested serum, muscle tissue, and adipose

tissue of cattle exposed to Zeranol in culture with normal and

cancerous human breast cells.

 

They found that serum, muscle extract, and adipose extract

significantly elevated DNA synthesis in normal cells, with adipose

extract 2.5 times more potent than muscle extract.

 

Serum stimulated DNA synthesis in one of two cancerous cell lines

tested.

 

" The greater mitogenic potency of Zeranol-adipose extract versus

Zeranol-meat extract indicates the presence of other unidentified

factors that may contribute to effects on breast tissue, " Dr. Lin's

team wrote in a meeting abstract. " The lack of growth response in

[one cancerous cell line] to Zeranol-serum indicates dependence on

estrogen receptors for mitogenic activity. "

 

" We must be very cautious at this stage, " Dr. Lin said. " At this

point all we have done is define that this factor is capable of

mimicking estrogenic action in gene amplification. In other words,

these compounds act like estrogen at the molecular level. Diet

studies need to be done in vivo, say in mice, to see how or if the

digestive process affects this chemical's action. "

 

" The FDA-approved levels of Zeranol are 150 ppb (parts per billion)

for meat, 300 ppb for liver, 450 ppb for kidney and 600 ppb for fat

tissue, "

 

Dr. Lin told Reuters Health. " Our laboratory samples had much lower

concentrations, 0.34 ppb in our 1% solution. " Dr. Lin again stressed

that these were laboratory samples developed and monitored under

ideal conditions.

 

Ann's NOTE: Many of us suspect that hormones added to meat causes

problems. This study indicates that scientists can track this. The

hormone appears to act as a promoter of breast cell growth.

 

Thanks to Reuters Health (Downloaded from Oncolink-U of Penn).

 

http://www.annieappleseedproject.org/beefadcelsti.html