Guest guest Posted August 30, 2005 Report Share Posted August 30, 2005 " HSI - Jenny Thompson " <HSIResearch HSI e-Alert - Testing...1...2...3 Mon, 29 Aug 2005 09:57:53 -0400 HSI e-Alert - Testing...1...2...3 Health Sciences Institute e-Alert **************************************************** August 29, 2005 Dear Reader, For diabetics, any trip to the doctor's office, no matter how routine, should be treated as an opportunity to take stock of various health issues that can be compromised by diabetes. In recent months, new research has emerged that every person with diabetes (either type 1 or type 2) needs to be aware of. More importantly, doctors of diabetics should take heed and run whatever tests are necessary to make sure liver function is carefully monitored. ----------- Texas test ----------- The most recent study assessing the danger of liver cancer among diabetics comes from researchers at the Baylor College of Medicine in Houston, Texas. The Baylor team analyzed information collected from a Medicare database that included more than 2,000 subjects over the age of 65 who had been diagnosed with liver cancer. These statistics were compared with a control group of more than 6,000 subjects who were randomly selected. The results: * More than 40 percent of the liver cancer patients were diabetic, compared to only 19 percent in the control group * The chance of having liver cancer was estimated as two to three times greater for patients with diabetes Writing in the April 2005 issue of the journal Gut, the researchers concluded that diabetes is an independent risk factor for liver cancer. This confirms the results of a 2004 Canadian study that examined rates of diabetes in more than 3,200 cancer patients and also found liver cancer risk to be about three times greater among diabetics. ----------- Early warning ----------- Another important result in the Baylor research concerned hepatitis C; a blood-borne infection that often develops into a debilitating liver disease called cirrhosis, which is a precursor to liver cancer. The Baylor team found that non-diabetic subjects who had hepatitis C were 24 times more likely to develop liver cancer. But those who were diabetic and also had hepatitis C were more than 35 times more likely to develop the cancer. Hepatitis C is currently the most widespread chronic blood-borne infection in the U.S., and diabetics are particularly susceptible to the virus. But for many hepatitis C patients, increasing vitamin K intake may prove to be a lifesaver. In the e-Alert " Special K " (3/1/05), I told you about a study from the School of Medicine at Osaka City University (Japan). Researchers recruited a group of 40 women with viral cirrhosis. Most of the subjects also had hepatitis C. The average age for the group was about 60. For two years, 21 subjects took a daily 45 mg dose of vitamin K2. The other 19 women took a placebo. Of the women in the K2 group, only two developed liver cancer, while nine of the women in the placebo group developed cancer. Larger studies will be needed to confirm any liver cancer preventive benefits of vitamin K2, but because of the length of the study, the researchers feel confident that K2 supplements may reduce the risk of liver cancer by as much as 20 percent in patients with viral cirrhosis. ----------- The K team ----------- You may have noticed that vitamin K2 was used in the Osaka study. And if you're wondering what K2 is and how it may differ from other forms of K, I'll call on HSI Panelist Allan Spreen, M.D., to explain: " The plant-based source of vitamin K (K1, or phylloquinone) seems to have no toxic effects in most any reasonable dose. But the synthetic form (K3, or menadione) has caused some liver toxicity and, rarely, a form of anemia when taken in high doses. There's also K2 (or menaquinones), but K1 and K2 are fine. As usual, it seems best to avoid synthetic forms, if possible. If the individual is on coumadin (blood thinner), he needs to talk with his doctor, as vitamin K can interfere with its effect. " In his Nutrition and Healing newsletter, Jonathan V. Wright, M.D., describes vitamins K1 and K2 as, " very safe, " and recommends 5 to 15 mg per day. Note that the K2 dosage in the Osaka study was quite higher than that. And although the supplement was well tolerated by the Osaka subjects, you should talk with your doctor or a healthcare professional for advice about a dosage level that would be right for you. As for dietary sources of vitamin K, Dr. Spreen tells me that dark, leafy green vegetables, such as kale and carrot tops, are the best for vitamin K1. " The highest amounts of it are in chestnut leaves and fish meal. Spinach leaves, cabbage leaves and cauliflower are also right up there. " In addition to those sources, broccoli, Brussels sprouts, endive, and lettuce are also abundant in vitamin K1, as are olive oil and avocados. Vitamin K1 is converted into K2 in the intestine, but we get some amount of K2 in meat, liver and egg yolk, and fermented products such as yogurt and cheese. And these sources reveal the basic difference between K1 and K2: K1 comes from plant sources, and K2 from animal sources. **************************************************** ....and another thing You can't throw a tin of Tetley's these days without hitting someone who's talking about the health benefits of green tea. But black tea has health advantages as well. In fact, it may help prevent oral cancer. Oral leukoplakia is a precancerous condition that's most common among tobacco users. White patches may appear on the gums, tongue and inside the cheeks of patients with this condition, and about half of all people with leukoplakia eventually develop oral cancer. In a recent issue of the Journal of Pathology, Toxicology, and Oncology, researchers report on a trial that tested 30 people with oral leukoplakia. For one year, half the group drank three cups of black tea daily. The other group abstained from drinking black tea. Samples of cells from leukoplakia mouth plaques were taken from all subjects at the beginning and end of the study period. When samples were analyzed, precancerous cellular damage was significantly reduced in the black tea subjects compared to those who didn't drink the tea. Oral cancer is responsible for more than 300,000 deaths each year - a number that might be considerably reduced with a few daily cups of Assam, Ceylon or Darjeeling (three common varieties of black tea). To Your Good Health, Jenny Thompson **************************************************** Sources: " Diabetes Increases the Risk of Hepatocellular Carcinoma in the United States: A Population Based Case Control Study " Gut, Vol. 54, No. 4, April 2005, ncbi.nlm.nih.gov " Diabetes Triples the Risk of Liver Cancer " Reuters Health, 3/8/05, reutershealth.com " Canadian Researcher Discovers Possible Link Between Diabetes and Liver Cancer " Press Release from the University " Role of Vitamin K2 in the Development of Hepatocellular Carcinoma in Women with Viral Cirrhosis of the Liver " Journal of the American Medical Association, Vol. 292, No. 3, 7/21/04, jama.ama-assn.org " Black Tea Prevents Oral Cancer " Maureen Williams, N.D., Healthnotes Newswire, 8/4/05, pccnaturalmarkets.com ************************* Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.