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Hydrogen peroxide keeps cells healthy

 

U.S. scientists say they've figured out how the human body

produces hydrogen peroxide to keep cells healthy. The report

by a team of researchers at Wake Forest University School of

Medicine, published in the journal Nature, said large amounts

of hydrogen peroxide are produced when the immune system is

activated in response to bacteria. The team used X-ray

crystallography to create a three-dimensional snapshot of

how the proteins interact. Scientists said a molecule known

as peroxiredoxin (Prx) helps control levels of hydrogen

peroxide. If levels of hydrogen peroxide become too high, the

cell's DNA and other proteins can be damaged. " It basically

acts as a sensor and warns the cell that levels are too high

and that the cell needs to respond, " lead author Thomas J.

Jonsson said in a news release. " Once that threat is gone,

Prx needs to go back to its normal state. " Prx becomes active

again by binding with a protein known as sulfiredoxin, the

report said.

 

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