Guest guest Posted June 28, 2006 Report Share Posted June 28, 2006 Bitter Melon Fruits have Important Components Resembling Insulin BITTER MELON (MOMORDICA CHARANTIA) Bitter Melon is a common vegetable eaten by many throughout Asia and the Far Eastern world. Bitter melon isn't its only name. Botanists and scientists call it Momordica charantia (botanical name).There are many nick-names including bitter gourd, carilla plant,wild cucumber,Kuguazi, African cucumber,karela, and its medicinal herb name in china, Kuguazi. Bitter melon is science-friendly.For example, you can find it in the " MERCK INDEX " , the chemist's and physician's encyclopedia of chemicals,drugs and biologicals. WHERE DOES IT COME FROM? Bitter melon is native to almost all tropical climates. It is common in Africa, China, the Far East, India, Brazil, the Caribbean, etc. HERE IN PART IS WHAT THE U.S. DEPARTMENT OF AGRICULTURE SAYS ABOUT BITTER MELON: " Bitter melon is used for tumors in Brazil, for malignant ulcers in Guam. Arubans take the decoction for hypertension,Puerto Ricans for diabetes;Hondurans as a depurative; Peruvians for colic and worms. Jamaicans for colds, constipation, fever and stomachache; Congolese use he leaf for colic, the seed for roundworm. Japanese use the plant for constipation, headache, and skin ailments.... " *James A. Duke, PhD., Chief, Germplasm Resources Laboratory, United States Dept. of Agriculture, Washington, D.C., quoted from HANDBOOK OF MEDICINAL HERBS (1985;pp315-316) -- WHAT IS THE SCIENTIFIC RESEARCH DATA ABOUT BITTER MELON? We think you will agree, that there is some- thing unique about this plant. Re: Its lowering of glucose concentrations, improving glucose tolerance, and promoting glucose disposal: " The mineral and amino acid analysis showed that the bitter gourd contained nutritionally useful quantities of the most essential mineral and amino acids. The blood sugar once lowered after 30 days did not increase even after 15 days of discontinuation of the treatment. " * *Journal of Ethnopharmacology 15(1):107-17 1986 Jan. " Investigations were carried out to evaluate the effect of Momordica charantia on the glucose tolerance of maturity onset diabetic patients. The juice of Momordia charantia was found to significantly improve the glucose tolerance of 73% of the patients investigated. " * *Journal of Ethnopharmacology 17(3):277-82 1986 Sept. " Cerrasee- A wild variety of Momordica charantia is traditionally prepared as a tea for the treatment of diabetes mellitus in the WestIndies and Central America. *Diabetes Research Clinical & Experimental 2(2):81-4 1985 Mar. " The hypoglycaemic effect of orally administered extracts of fruits of cultivated Momordica charantia (Karela) was examined. The results suggest that orally administered karela extracts lower glucose concentrations independently of intestinal glucose absorption and involve an extra pancreatic effect. " * *Planta Medica 56(5); 426-9 1990 Oct. " The effect of Karela (Momordica charantia), a fruit indigenous to South America and Asia, on glucose and insulin concentrations was studied in nine non-insulin-dependent diabetics and six non-diabetic rats. These results show that karela improves glucose tolerance in diabetes. Doctors supervising *Asian* diabetics are aware of the fruit's hypoglycemic properties. " **British Medical Journal-Clinical Research 282(6279); 1823-4 1981June 6. " An aqueous extract from the unripe fruits of the tropical plant Momordica charantia was found to be potent stimulator of insulin release from beta cell rich pancreatic islets isolated from obese-hyperglycemic mice. Studies of 45 Ca fluxes suggest that the insulin releasing action is a result of perturbations of membrane functions. In support for the idea of direct effects on membrane lipids, the action of the extract was found to mimic that of saponin. " * *Acta Biologica et Medica Germanica 41(12):1229-40 1982. " A hypoglycemic peptide, Polypeptide-p has been isolated from the fruit seeds and tissue of Momordica charantia. Polypeptide-p is a very effective hypoglycemic agent when administered subcutaneously to gerbils, langurs and humans. " * *Journal of Natural Products 44(6):648-55 1981 Nov.-Dec. " Extracts of Momordica charantia fruit pulp, seed, and whole plant were tested for their hypoglycemic effects on normal and diabetic rat models. The results indicate the presence of non-sapogenin hypoglycemic compound(s) in Momordica charantia fruit pulp and the activity is probably mediated either by improving the insulin secretory 'capacity ofthe B cells or by improving the action of the insulin. " * *Planta Medica 59(5):408-412 1993 " The Bitter Melon or Balsam Pear - is cultivated as a tropical vegetable in South America, Asia, and Africa where it has been used as a traditional therapy for diabetes in a variety of cultures of these countries. One isolate of Momorica, Charantin is a mixture of steroidal glycosides and compares favorably to " tolbutamide " , an allopathic drug commonly used as a oral hypoglycemic agent. Another isolate, polypeptide-P has been shown to lower blood glucose when administered via subcutaneous injections. A variety of oral extracts have been shown to lower blood sugar and improve glucosetolerance in both human and animal studies. *Chakravarthy BK, Gupa S, and Gode KD: Functional beta cell regeneration in the islets of Pancreas in alloxan induced dibetic rats by epicatechin. Life Sc 31:2693-7, 1982 " ....The results indicated that M. charantia fruits and seeds contained components that resembled insulin in inhibiting hormone- induced lipolysis... " * *Wong CM, Yeung HW, Ng TB: Screening of (family Cucurbitaceae) for compounds with antilipolytic activity. *Journal of Ethnopharmacology 13(3):313-21, July 1985. http://home.istar.ca/~hlth2000/bittermelon.html --------------- BITTER MELON AS AN ALTERNATIVE TREATMENT FOR DIABETES In Myanmar (Burma), China and India, it is highly prized for its anti-diabetic activity.Myanmar traditional physicians prescribe bittermelon to diabetic patients. Doctors in India are so confident of bitter melon's positive effect on diabetes,they dispense bitter melon in some of the most modern hospitals. According to James Duke of U.S Department of Agriculture, bitter melon has attained favor in China as a monoherbal medicine for diabetes mellitus. Bitter melon has twice the potassium of bananas, and it has been shown to increase the number of *beta cells* -those which produce insulin, in the pancreas. PREPARATION- Bitter melon is available through most Filipino and/or Asian grocery stores, and some farmers markets and is also available in supplement form. The appropriate method of administering bitter melon is to make the extract from the fruit, vines, and leaves of the plant and either drink it as a juice, tea or administer it as a retention enema. Some say that drinking the juice or tea will result in the breakdown of the active components by stomach acids, therefore a retention enemawould be a more efficient route. Momordica charantia (Bitter melon): Therapeutic Actions, Clinical Indications, and more Diabetic and Other Metabolic Neuropathies Abstracts THE INFLUENCE OF MOMORDICA CHARANTIA FRUIT JUICE ON PERIPHERAL NERVE STRUCTURE IN EXPERIMENTAL DIABETES Serasee is believed to work in a holistic manner. It is believed to work best if your food and water are clean and natural, and your heart and mind are pure. If you eat foods with a lot of chemicals it won't work so well. If you are full of toxins, use sparingly at first, as purification reactions may be strong Mormodica works from the subtlest levels to adjust you toward health, and works best with your total cooperation in the way of diet, attitude, etc. ------------- Let's not sugarcoat it. Glucose-lowering drugs can do more harm than good. The natural therapies used at the Whitaker Wellness Institute for diabetes help keep blood sugar levels in check without the side effects of drugs. These drugs usually succeed in lowering blood sugar levels, but may increase the death rate from heart attacks. (this is listed as a common side effect!) These drugs also are associated with weight gain, elevated cholesterol and triglyceride levels, nausea, diarrhea, constipation, stomach pain, drowsiness, and headache. The Natural Pharmacist: Natural Treatments for Diabetes includes up-to-date information on diabetes and chromium,alphalipoic acid, evening primrose oil, fenugreek, Gymnema sylvestre, magnesium, Momordica charantia, Coccinia indica, Pterocarpus marssupium, niacinamide, and bilberry treatments. --------------- High-fiber supplements, such as psyllium, guar gum (found in beans),24 pectin (from fruit) oat bran, and psyllium have improved glucose tolerance in some studies. Positive results have also been reported with the consumption of 1–3 ounces of powdered fenugreek seeds per day. Many doctors advise people with diabetes to eat a diet high in fiber.Focus should be placed on vegetables, seeds, oats, and organic whole-grain products. The fatty acids (omega-3s) in cold water fish also may afford some protection from diabetes. Incorporating a fish meal (alaskan salmon for example) into a weight- loss regimen was more effective than either measure alone at improving glucose and insulin metabolism and high cholesterol. Vegetarians have been reported to have a low risk of type 2 diabetes. When people with diabetic nerve damage switch to a vegan diet (no meat or dairy), improvements have been reported after several days. mrsjoguest Quote Link to comment Share on other sites More sharing options...
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