Guest guest Posted October 1, 2007 Report Share Posted October 1, 2007 Reposting part o f the newsletter, Health e-Tips. Thought this was interesting. blessings Shan Dear Reader, Now that Big Pharma has cornered its own statin drug market, it decided it needed a new way to profit from cholesterol. Lowering it is old news, so they've moved on to the opposite end of the spectrum: Merck & Co. has spent the past year developing a drug that will raise levels of HDL cholesterol. HDL is considered the " good " form of cholesterol: Researchers believe it carries cholesterol away from the arteries and back to the liver where it can be processed and excreted from the body. Low levels of HDL cholesterol have been linked to increased risk of cardiovascular disease. So, obviously, raising them is a good thing. But the way Merck is going about it is a bit underhanded if you ask me. The primary active ingredient in its new drug, called Cordaptive, is nothing more than an extended-release form of the nutrient niacin. So how are they going to patent -- and profit from -- an all-natural vitamin, you might wonder? Well, they've combined the niacin with a drug called laropiprant. No, it doesn't have HDL-boosting abilities of its own. And no, it doesn't increase the effectiveness of the niacin. Laropiprant has the singular purpose of preventing the facial flushing that can occur when you take large quantities of niacin. While this side effect can be bothersome, it's certainly not life-threatening. But according to Merck's research, fewer patients experienced this flushing with the niacin/laropiprant combination than with niacin alone. That's fewer -- not none. So apparently, adding the drug isn't a fool-proof solution. The results were good enough for regulators to accept Merck's marketing application, though. But here's what they won't want you to know when the FDA approves Cordaptive and Merck launches their gazillion-dollar ad campaign for it: You can get extended-release, " flush-free " niacin formulations in just about any natural food store or vitamin shop. In fact, Dr. Wright has been recommending them for years! He typically advises his patients to use a form of niacin called inositol hexaniacinate. I'm sure that these versions of niacin escaped the Merck R & D team's notice during its research, though, and that they stuck with " regular " niacin, which is much more likely to cause flushing. In other words, they stacked the deck against the natural version so that their formula would come out victorious in this little contest of wills. Once again, the devil's in the details… No doubt Coraptive will hit the market with a bang next year. And Merck will likely make a pretty penny from it. But those of us who know better will get the same heart- healthy results without spending a fortune, and without putting ourselves at risk for whatever side effects will undoubtedly emerge from their attempt to patent nature by combining it with something thoroughly unnatural. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2007 Report Share Posted October 2, 2007 A company marketing a non-flush niacin product, claims that " niacin hexa-niacinate " is not effective in raising HDL in the human body. I'll search for the company's name. They claim that their niacin product " does " raise HDL. jp - surpriseshan2 MCS-Canada Monday, October 01, 2007 8:19 AM Health e-Tips - Sins of omission --- New Drug - for increasing HDL Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.