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My name is Pat and I live in Ontario. I have OA in my back, both hips, both

knees, and

both ankles! grrrrrrrrrr. I have anklosing spondylitis of the back. I

ordered some of the

juice from a man that came after me from a pain group and then a kind man

named,

Neil, told me I had been taken. The juice has already been paid for. Does

anyone know

anything about this Mangosteen juice? Thanks for having me and God Bless,

Pat

 

 

 

The Lord bless you and keep you; the Lord make His face

to shine upon you, and be gracious to you; the Lord lift

up His countenance upon you and give you peace.

Numbers 6:24-26

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Beware it is a scam, read this article and the email from Donna.

 

From a google search.

http://chetday.com/mangosteen.htm

Mangosteen:

A Friendly Skeptic Looks at Mangosteen

By Dr. Ralph Mossfrom CancerDecisions.com Newsletter

When I wrote Cancer Therapy in the early 1990s, I had the bright idea of putting my mailing address in the book in the hope that some readers would send me information on new treatments. Little did I imagine that such communication would become a torrent of proposals. Today, hardly a day goes by without my being made aware of some new "cure." Would that a fraction of these panned out as well as proponents claimed!

One of the latest in this long line is an exotic fruit drink called mangosteen, or XanGo. Mangosteen should not be confused with mango, an entirely different plant. It is part of a group known as the Guttiferae, a family of mainly tropical trees and shrubs that secrete an acrid yellow resinous juice. Mangosteen's scientific designation is Garcinia mangostana (Campin 2004). It is reputedly named after a French explorer, Jacques Garcin (1673-1751). In Europe and North America, the most recognizable member of this family is the popular herb, St. John's wort.

No one knows exactly where and when the mangosteen was first cultivated. One botanist, Julia F. Morton, believes it originated in the Moluccas and the Sunda Islands. Yet there are also wild mangosteen trees in the forests of Malaya. Some experts say the trees were first domesticated in Thailand or Burma. But in the 19th century, botanists brought seeds to Europe and America. Valiant attempts were made to cultivate the 18-foot high trees in Africa, the Caribbean and central America. But the plant is considered "ultra-tropical" and sensitive: nursery seedlings die at 45º F. In fact, there are few if any mangosteens growing in the continental US. A lone American tree in Florida was said to have yielded a single fruit...and then died. That was the beginning and end of the American mangosteen "industry."

But attempts continued to bring mangosteen to Europe and America as a food. "Despite the oft-repeated Old World enthusiasm for this fruit," says Morton, "it is not always viewed as worth the trouble to produce. In Jamaica, it is regarded as nice but overrated; not comparable to a good field-ripe pineapple or a choice mango."

The mangosteen fruit is the size of a small apple, purple colored, with a hard rind. Inside there are typically five to seven seeds surrounded by a sweet, juicy cover (or aril). The pulp, which is said to resemble a pineapple or peach in taste, is reputed to be a very delicious food - in Asia it is sometimes called the queen of fruits in honor both of its flavor and its economic importance.

Uses in Traditional Medicine

For many years dried mangosteen fruits have been shipped from Singapore to Calcutta and then on to China for medicinal use. As to its many uses in folk medicine, here is what botanist Julia Morton has written:

 

"The sliced and dried rind is powdered and administered to overcome dysentery. Made into an ointment, it is applied on eczema and other skin disorders. The rind decoction is taken to relieve diarrhea and cystitis, gonorrhea and gleet [a watery discharge, ed.] and is applied externally as an astringent lotion. A portion of the rind is steeped in water overnight and the infusion given as a remedy for chronic diarrhea in adults and children.

"Filipinos employ a decoction of the leaves and bark as a febrifuge and to treat thrush, diarrhea, dysentery and urinary disorders. In Malaya, an infusion of the leaves, combined with unripe banana and a little benzoin is applied to the wound of circumcision. A root decoction is taken to regulate menstruation. A bark extract called 'amibiasine', has been marketed for the treatment of amoebic dysentery."

Morton also writes that "[t]he rind of partially ripe fruits yields a polyhydroxy-xanthone derivative termed mangostin, also beta-mangostin. That of fully ripe fruits contains the xanthones, gartanin, 8-desoxygartanin, and normangostin. A derivative of mangostin, mangostin-e, 6-di-O-glucoside, is a central nervous system depressant and causes a rise in blood pressure." A more complete listing of constituents is given at ethnobotanist Dr. James Duke's informative and useful Phytochemical and Ethnobotanical Databases (Duke 2004).

We can conclude then that mangosteen has many uses in folk medicine, and as such, it can join a fairly long list of plants that can be considered as promising sources of new medicines.

XanGo on the Go

In this age of frenzied commercialism, entrepreneurs are always on the lookout for ways to make it big in the natural medicines market. Under such conditions, however, new medicines of botanical origin cannot be developed or tested in an orderly way.

A common feature of the way in which natural medicines such as mangosteen are promoted is the use of network marketing. This involves the retailing of products through the use of independent distributors. These distributors are then encouraged to build and manage their own sales force by recruiting, motivating, supplying, and training others to sell products. Compensation in such arrangements includes the distributor's own sales as well as a percentage of the sales of his or her entire "downline" (i.e., all those people signed up by an individual, who in turn go on to become salespeople). The term network marketing is virtually synonymous with the older but now somewhat disreputable term 'multi-level marketing' (MLM).

Network marketing turns mere consumers into determined marketers who aggressively sell their product, often to their own friends, relatives and neighbors. The more people they can recruit into the growing network the more money they themselves make. A sophisticated marketing blitz, including books and pamphlets, seemingly objective newsletters, press releases and chattering websites, inflate the importance of a product, creating a buzz that only dies away when the huge supply of potential customers and salespeople is finally exhausted. Or when, as it has on occasion, the government finally steps in. But the essential requirement for a successful MLM operation of this sort is a kernel of promising-sounding scientific evidence, coupled with a credible and compelling story, a compliant doctor willing to underwrite the concept, and finally some patients (who may themselves be distributors) willing to testify that the product led to astounding cures.

Aloe vera, colloidal minerals, gingko biloba and ginseng were all popularized in this way. But perhaps the most memorable example of a network marketing stampede is noni juice, a once totally obscure Polynesian fruit that became the basis of a huge industry. Tahitian Noni International, formerly called Morinda, last year claimed to have passed the two billion dollar sales mark! This is the sort of performance that makes get-rich-quick artists drool.

The techniques of network marketing, honed through decades of trial and error, are now being used by a Utah-based company to position mangosteen as the latest "miracle cure" craze. The price of their XanGo mangosteen juice is currently $37 per bottle (or four for $100). You have to ask yourself: who on earth would pay that much for a bottle of fruit juice, no matter how delicious it might be? The reason the marketers can succeed in selling juice at this price is obvious: when people are suffering from medical conditions for which there does not appear to be much hope, or for which the orthodox medical recommendations are too toxic or expensive, they will actively seek alternatives. And then someone, oftentimes someone they trust, such as a friend or neighbor, convinces them to give some new product a try. Products such as mangosteen exploit humanity's understandable desire to discover simple and painless solutions to intractable problems.

Now that the commercial ball is rolling an increasing number of mangosteen brands are reaching the market. But for the time being the market leader is XanGo (www.myxango.com). A visit to their website triggers an audio webcast from a very pleasant sounding young lady, who assures us that "by integrating the Internet, teamwork, and personal mentoring, MyXanGo.com provides you a vehicle to improve the areas of your life that are most important to you, and we do it for FREE."

I listened in amazement to her polished spiel and the brazen intrusiveness of this message. I was particularly amused when she said, "You should know that this message is not about selling." Right. "It's not about false claims and outlandish statements." Sure. "It's about sharing facts to help you decide if now is the right time in your life to consider XanGo." Really.

The rhetoric gets even more effusive. A March 2004 press release from one seller proclaims: "Mangosteen is now on an unstoppable march to conquer the world" (Goss 2004). Put this way it sounds rather ominous…almost like a cross between Osama bin Laden and the Attack of the Killer Tomatoes.

Xanthones

As stated, one requirement for a successful network promotion is that there be at least a kernel of scientific truth around which exaggerated claims can be assembled. As with noni juice, mangosteen is not entirely without scientific documentation. The problem, as usual, is that the claims for mangosteen are inflated till they far outpace what has been established through careful experimentation.

Some mangosteen promoters have mined James Duke's famous ethnobotanical database for confirmation of their product's value. And, indeed, Dr. Duke confirms that the plant contains several interesting components. But so do thousands of other plants in his voluminous database. For most of the chemicals contained in this fruit (such as beta-mangostin, catechins, cis-hex-3-enyl-acetate, gamma-mangostin, gartanin, garcinones) the database lists NO particular biochemical activities. Only the compound called "mangostin" seems to have some scientific backing for its antibacterial, antiseptic and fungicidal properties (Recio 1989). Yet scores of mangosteen websites now cite Duke's database as scientific justification for this product. In reality, Dr. Duke has absolutely nothing to do with any mangosteen distributor and is not particularly enthusiastic about the product.

Much is made of the xanthone connection. According to the MyXanGo.com website: "There are over 200 xanthones in nature. Each xanthone can have specific effects on the body. What's remarkable about the mangosteen is that there are over 40 xanthones identified in the pericarp, or rind, making it the single most xanthone-rich source in the world….Only six of the xanthones have been studied in depth. While we don't know fully why the mangosteen works on such a wide variety of physical conditions, we know it has to do with being the world's most potent source of xanthones. Each xanthone has its own effect, and when combined, they take on a synergistic quality that supports the health of the entire body."

But all of this is speculative. It is undoubtedly true that there are many xanthones (a kind of antioxidant) in mangosteen. In fact, according to the Merck Index (11th Ed., p. 5613) the first scientifically defined substance to be derived from mangosteen was the xanthone mangostin. This was isolated by a German scientist named Schmid in 1855. In 1979, mangostin was found to have significant anti-inflammatory and anti-ulcer effects in rats (Shankaranarayan 1979). Yet although mangosteen's xanthones have been known for almost 150 years, there are still only 19 PubMed articles on these xanthones and none of these articles concerns the use of xanthones in the actual clinical treatment of human disease. So I would say the jury is still out on their effectiveness in treating anything.

The main XanGo website also claims that the antioxidant ORAC (oxygen radical absorbance capacity) value of mangosteen is the highest of all edible plants. "It is so potent that literally I know of nothing else in the supplement market that can possibly come even close to it," says J. Frederic Templeman, MD, a Georgia family practitioner who is interviewed at the MyXanGo website. Many other XanGo-promoting websites repeat the claim that while the previous champion, prunes, have an ORAC value of 7,000 per ounce, mangosteen has an ORAC value of 17,000 to 24,000.

Yet XanGo sites claim that "a new champion" has been born in the worldwide contest for ORAC supremacy. But where in the scientific literature is the ORAC value of XanGo published? The source of these numbers is hard to track down. For instance, the Sunsweet prune website states that 100 grams (3.5 ounces) of prunes have an ORAC value of 5,770. While the ORAC values for most fruits and vegetables have been determined by standard laboratories and published in scientific journals, this is not so for mangosteen. I have not seen independent confirmation of these confidently promulgated claims. However, even if we assume for the sake of argument that the figures cited are indeed accurate, it must be pointed out that merely having an astronomically high ORAC value does not in and of itself confer any particular advantage. Not all antioxidants that are confirmed as present in the laboratory can be absorbed by human beings. And there is a limit to how much we can benefit from an increased intake of antioxidants.

According to Dr. Ronald Prior of the US Department of Agriculture Research Service at Tufts University, Boston, Massachusetts, "a significant increase in antioxidants of 15 to 20 percent is possible by increasing consumption of fruits and vegetables, particularly those high in ORAC value." However, in order to have a significant impact on plasma and tissue antioxidant capacity one can only meaningfully increase one's daily intake by 3,000 to 5,000 ORAC units. Any greater amount is probably redundant. That is because the antioxidant capacity of the blood is tightly regulated, says Dr. Prior. Thus there is an upper limit to the benefit that can be derived from antioxidants. Taking in 25,000 ORAC units at one time (as reputedly occurs with mangosteen) would be no more beneficial than taking in a fifth of that amount: the excess is simply excreted by the kidneys.

Marketers of the drink have widely claimed that XanGo has exceptional health-giving properties based on its very high ORAC score. (ORAC stands for oxygen radical absorbance capacity - a measure of the antioxidant value of a substance.) But having a high ORAC value does not necessarily confer any health advantage.

According to Dr. J. Frederic Templeman, a Georgia family practitioner who has written a small book on mangosteen, and who is widely quoted by XanGo marketers, if you take these antioxidants "you aren't going to probably have a heart attack as fast as someone who doesn't take them" and consuming them could therefore constitute "literally the difference between life and death." Although I myself have written a book on the subject of the benefit of antioxidants (Antioxidants Against Cancer), I would say it is a tremendous stretch to claim that antioxidants are predictably going to save anyone's life. Good health is achieved through a combination of many factors, hereditary as well as environmental.

Effects on Cancer

At the XanGo website, a company spokesperson interviews Dr Templeman on the subject of mangosteen's beneficial effect on cancer. They both agree that a single test tube experiment is proof of the anticancer value of the juice:

Dr. Templeman: "That's striking."

XanGo spokesperson: "It's incredible."

At various other websites devoted to XanGo (and there are now over 21,000 of them!) we read in glowing terms about both the supposed quantity and quality of scientific research on this previously obscure fruit.

Reality Check

So it is high time for a reality check. Has mangosteen really been thoroughly studied in terms of its effect on cancer and a host of other diseases? Or is this simply a wild extrapolation driven by strong commercial motives?

Dr. Templeman refers to 44 scientific publications on this topic but there are just 29 articles on the topic of Garcinia mangostana in PubMed, the US National Library of Medicine database of 14+ million citations. A total of four of these studies relate to cancer. In one test tube experiment it was shown that a xanthone found in mangosteen kills cancer cells as effectively as many chemotherapeutic drugs. It also appears (on the basis of limited data) that compounds found abundantly in mangosteen can inhibit the harmful Cox 1 and Cox 2 enzymes, and can also induce programmed cell death (apoptosis) in aberrant cells (Ho 2002). Mangosteen thus joins a fairly long list of naturally derived compounds that might potentially have some anticancer activity.

These 29 articles do not constitute a wealth of data. For example, by contrast, PubMed lists over 2,300 articles on the topic of vitamin C and cancer, 125 of which refer to clinical trials. There are a similar number of studies on vitamin E and cancer. There are 835 studies of melatonin and cancer, and a truly impressive 16,000 on polysaccharides and cancer, including 536 clinical trials and 277 randomized controlled trials (RCTs).

Yet, we're to believe that four test-tube experiments constitute - to quote the aforementioned Dr. Templeman - "mountains of evidence" on the benefits of XanGo.

According to the promotional website of one of XanGo's many "independent distributors" at http://bjsbytes.com/Xango/Questions.htm:

 

"...much of the science behind xanthones is predominantly available to those in the medical community until recently. Many of the clinical studies on xanthones have been done in universities and testing facilities throughout Asia and have recently started to catch the attention of Western researchers."

But is this true? Reputable researchers the world over, including those in Asia, publish in PubMed-listed journals. For example there are over 63,000 articles on cancer in PubMed in the Japanese language. Yet despite the website's misleading talk about "clinical studies," PubMed does not contain a single clinical trial of mangosteen in the treatment of cancer, or any other disease. Perhaps these promoters don't realize that a clinical study is not something done in a laboratory, but a study that by definition is carried out on living patients. Laboratory studies on cell lines or even animals do not qualify for the title 'clinical study'.

Thus, despite what you may read at any one of those 21,000 promotional websites, very little scientific evidence exists concerning mangosteen's anticancer activity in humans.

In my opinion, what we have here is simply an overpriced fruit drink. Fruit drinks are often healthful beverages. But the only reason I can see that the promoters of mangosteen can get away with charging $37 for this product is that they are playing on patients' hopes and fears in a cynical way. Without the health claims, open or implied, the product could only be sold for at most $5 or $6 (which, for example, is the cost of antioxidant-rich pomegranate juice).

The mangosteen phenomenon is a reprise of the aloe vera, gingko biloba, and especially the noni juice story, complete with exaggerated claims for the health benefits of an exotic fruit. It should come as no surprise that both the President and the Chief Financial Officer of Xango once worked for Morinda (now called Tahitian Noni International).

Compounds found in plants have long been of great interest to cancer researchers. We must never forget that about one-fifth of all chemotherapeutic agents (including Vincristine, Vinblastine, Etoposide, Teniposide, and Taxol) are ultimately derived from plant sources. Many of these took a long time to pass through the regulatory process, since serious research into botanical medicine often goes begging for financial and intellectual support. Starved of funds in this way, the riches of the natural world are often neglected by mainstream science, only to be plundered by less scrupulous organizations. The patient loses twice - by not having the fruits of serious research and by being deceived by slick operators posing as friends and benefactors. Some may even opt for unproven miracle juices in lieu of more certain therapies that might save their lives.

When it comes to cancer, we truly live in a topsy-turvy world.

 

 

 

Note from Chet: Be sure to sign up for Dr. Moss's excellent newsletter at his website.

References:

Campin, Jac. Guide to Plant Relationships (for food allergy and intolerance identification),Version 12 (14 April 2004. Retrieved April 27, 2004 from: http://www.purr.demon.co.uk/Food/RelatedPlantList.html

Duke, James, ed. Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture, Agricultural Research Service, Accessed April 27, 2004 from: http://www.ars-grin.gov/cgi-bin/duke/farmacy2.pl?1228

Hedrick, U.P. (ed.) 1972. Sturtevant's Edible Plants of the World. NY, NY: Dover Publications, Inc., 1972. Downloaded from: www.swsbm.com/

Ho CK, Huang YL, Chen CC. Garcinone E, a xanthone derivative, has potent cytotoxic effect against hepatocellular carcinoma cell lines. Planta Med. 2002 Nov;68(11):975-9.

Matsumoto K, Akao Y, Kobayashi E, Ohguchi K, Ito T, Tanaka T, Iinuma M, Nozawa Y. Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines. J Nat Prod. 2003 Aug;66(8):1124-7.

Moongkarndi P, Kosem N, Kaslungka S, Luanratana O, Pongpan N, Neungton N. Antiproliferation, antioxidation and induction of apoptosis by Garcinia mangostana (mangosteen) on SKBR3 human breast cancer cell line. J Ethnopharmacol. 2004 Jan;90(1):161-6.

Morton, Julia F. Mangosteen. In: Fruits of Warm Climates. Self-published. Miami, FL, 1987, pp. 301-304. ISBN: 0-9610184-1-0

Nakatani K, Nakahata N, Arakawa T, Yasuda H, Ohizumi Y. Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells. Biochem Pharmacol. 2002 Jan 1;63(1):73-9.

ORAC value of Sunsweet prunes: http://www.sunsweetdryers.com/Sunsweet.htm

Recio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research. 1989:3(4)117-125.Shankaranarayan D, Gopalakrishnan C, Kameswaran L. Pharmacological profile of mangostin and its derivatives. Arch Int Pharmacodyn Ther. 1979 Jun;239(2):257-69.

 

 

 

 

On Sat, 9 Apr 2005 14:08:00 -0400 (Eastern Standard Time) "twin5643" <twin5643 writes:> > Hello, my name is Donna, I joined your group a long time ago after > breaking> my back. It has been two years on Memorial day. I am not sure if I > joined> after my initial accident where I had an L-1 compression fracture or > after> that when only three weeks out of the hospital I fell down four > concrete> steps and had to have 5 vertabra removed and three SS herrington > rods put in> , also cages and pins, wires and screws. The cages had bone grafts > in them.> I also suffer from Fibro, degenerative joint disease, interstitial > cystitis> arthritis, extreme fatigue and many other things. Oh, my left hip > has hurt> so severely for the last 12 years I could not get comfortable enough > to> sleep well. In November of 2004 I started having too many heart > beats which> are called PVC's. I have a pace maker also. Lots of things for > someone only> 48 years old. My health started really declining in 1979 when I had > weight> loss surgery in Houston , Texas where I lived at the time . ( We > have been> in NC since 1989) The surgery was very similar to the stapling > procedure> but they wrapped my stomach with marlex . I got infection and had a > hospital> stay of six months that time. If it was on the list of possible risk > I got> it !!

 

> Over the years I have had about 15 surgeries since then.

 

> Two weeks ago some very good friends of mine came over and knowing > how much> pain I stay in wanted me to try a product that is made from > Mangosteen juice> They gave me two 25 oz bottles and I drink 2 oz before breakfast > every> morning. To my amazement after only five days my hip stopped > hurting> completely, the extra heart beats stopped, my muscles feel better > and my> general over health is 90 % improved !! I sleep all night now and if > I do> wake up to go to the restroom I do not have to lean on a cane to be > able to> walk. As a matter of a fact I am no longer using my cane.

 

> I could not wait to share with you all how drinking the juice has > changed> the way I feel.

 

> The mangosteen is very high in Xanthones and has more antoxidants > than any> other fruit. If you would like more information on this send me your > phone> number or e-mail and I would be glad to share with you the > information I> have. I did become an independent distributor of the juice so now I > can feel> good and make money to while sharing with others while I am waiting > half of> my life for social security to start my disability benefits. Who > knows I may> not have to try and get it if I can show others how much this > product has> changed the way I feel. If you would like to order a bottle to try > please> use my distributor ID # 5193931 . My name is Donna Zabodyn. If it > works for> you I would love to hear from you and if you are interested in > buying> wholesale and making money to after that I would be glad to get you > started >

 

> I did not share this with you all to just get interested clients. If > none of> you ever purchased a bottle from me I encourage you to at least try > it and> see if it helps your pain too. Go to and check out the information > about it> Some of the testimonials are awesome. It may not be for you but it > has> proven to help people with everything imaginable. Good luck and I > pray this> helps some of you not have to have the spinal injections and things > I have> endured that did not work.

 

> One last thing, I do not encourage anyone to stop meds without > talking with> your Dr first but I was able to stop my Soma, vicodan ( I was > taking 15mg> at a time) hydroxizine, Macrodantin, Urised, and the lopressor for > my extra> heart beats. I will be checking in to see if any of you can benefit > from> this great product Xango is offering. Thanks and prayers to all of > you.

 

> > > Donna Zabodyn

 

> Here is some info on the Xango

 

>

 

> 1.What is Xango™?

 

> Xango™ is the first commercial product to feature the entire fruit > and> complete nutrition of the whole mangosteen fruit. Xango™ is an > exciting new> category creator, unleashing a new superstar in the world of dietary > heath> supplements.Xango™ is also the name of the company who markets this > new> functional, nutritional beverage.

 

>

 

>

 

>

 

> 2.What does Xango™ mean?

 

> The brand name Xango™ was created from two words: Xanthones and > Mangosteen.

 

>

 

>

 

>

 

> 3.Is Xango™ a medicine?

 

> No. It is a health supplement. No medical advice is given or > implied. In all> health aspects, the advice of competent, licensed medical > professionals> should be sought.

 

>

 

>

 

>

 

> 4.What does Xango™ taste like?

 

> Xango™ tastes great! It’s difficult to describe the flavor with > accuracy.> Some people detect a hint of strawberry, while others are reminded > of kiwi,> pomegranate, or grape. The complex flavor of this sweet, dry > beverage,> however, wins instant praise from all who try it.

 

>

 

>

 

>

 

> 5.What are the ingredients of Xango™?

 

> Xango™ is 100% natural. It has no artificial flavors or colors and > no added> sweeteners. Why? It doesn't need it!

 

>

 

> Ingredients: Reconstituted garcinia mangostana juice from whole > fruit, apple> juice concentrate, pear juice concentrate, grape juice concentrate, > pear> puree, blueberry juice concentrate, raspberry juice concentrate, > strawberry> juice concentrate, cranberry juice concentrate, cherry juice > concentrate,> citric acid, natural flavor, pectin, xanthan gum, sodium benzoate, > potassium> sorbate.

 

>

 

> One serving = 1 fl. oz. (30 ml)

 

> Servings per container = 25

 

>

 

> Calories = 10

 

> Calories from fat = 0

 

> Total Fat = 0 g

 

> Sodium = 0 mg

 

> Total Carbohydrate = 3 g

 

> Sugars = 2 g

 

> Protein = 0 g

 

>

 

>

 

>

 

> 7.What is Mangosteen?

 

> The mangosteen (Garcinia Mangostana) is a tropical fruit considered > to be> one of the finest tasting fruits in the world and has earned the > popular> title "Queen of Fruits." The mangosteen tree is found predominantly > in> Southeast Asia in countries like Cambodia, China, Indonesia, > Malaysia,> Singapore, Taiwan and Thailand.

 

>

 

> The fruit itself consists of the following segments:

 

> ·Pericarp (sometimes spelled Pericarb): A thick dark purple, smooth > rind> that encloses the fruit segments.

 

> Pulp: 4 to 8 triangular segments of snow-white, soft flesh. Known > for its> excellent flavor, the mangosteen is proclaimed by many to be the > best among> tropical fruits.

 

>

 

>

 

>

 

> 8.If the Mangosteen fruit is so beneficial, then why have we never > heard of> it before?

 

> Anyone who has lived in, or visited, South East Asia during the > season of> the mangosteen fruit knows that the fruit is very popular. Natives > have> coined it to be the, "Queen of Fruits". However, it is generally > unknown in> the US because of its growing conditions. Many scientists are > researching> this fruit in Asia and Australia but not in the US.

 

>

 

>

 

>

 

> 9.What benefits does the Mangosteen fruit have in dealing with the > immune> system?

 

> The pericarp of the mangosteen fruit contains an active chemical > group known> as "xanthones". These chemicals along with the others > (polysaccharides) aid> the bodies immune system in the following ways:

 

>

 

> • Anti-bacterial – inhibits the reproduction of staphylococcus > aureus> bacteria (both normal and penicillin resistant). The polysaccharides > in the> pericarp stimulate immune cells to kill bacteria.

 

> • Anti-viral – xanthones, as a whole, possess many anti-viral > activities.> The only study on the xanthones of the mangosteen fruit was > conducted on> alpha and gamma mangostin and the results showed that these > xanthones> inhibited the viruses from replicating. If a virus cannot replicate > it> cannot infect other body cells.

 

> • Anti-fungal – the xanthones of the mangosteen were tested > experimentally> against three common fungi and were proven capable of effectively > inhibiting> there growth.

 

>

 

> Read more Xango™ benefits

 

>

 

> 10.What benefits does the Mangosteen fruit have in regards to the > digestive> system?

 

> The mangosteen fruit has been used for centuries in dealing with > diseases> associated with the digestive system. In North America these > conditions are> usually nothing more than inconveniences. However, in other areas of > the> world these conditions can be lethal. The people of South East Asia > have> been using the mangosteen fruit for treating dysentery and diarrhea > for> centuries. The pericarp of the mangosteen fruit contains xanthones > that mey> help to inhibit the inflammation and thus reduce the effects of > these> diseases. It is interesting to note that it is because of this use > that> scientists are investigating the effects that the xanthones have on > other> inflammatory conditions in the body.

 

>

 

> Product AnswersXango™ Juice Business Site

 

> 11.Can the mangosteen fruit be grown in San Diego? Other mangoes > seem to do> well here?

 

> The mangosteen fruit is not related to the mango. The mango can grow > outside> of the tropics, but the mangosteen cannot. Several times over the > past> centuries, individuals have unsuccessfully tried to grow the > mangosteen tree> in the United States.

 

>

 

>

 

>

 

> 12.I have a friend who asked me if mangosteen acts like a stimulant. > She> says that if she eats anything with caffeine or something similar > (ephedra),> her heart will start to beat irregular after awhile. Is this the > case with> the Xango™ preparation of the mangosteen fruit?

 

> It does give energy but not by stimulating the sympathetic nervous > system so> there is no increase in heart rate or blood pressure. It is > perfectly safe> to take this product without the concerns in an irregular heart > rate.

 

>

 

>

 

>

 

> 13.I want to start giving Xango™ (Mangosteen fruit) to my 3 years > old son,> what dosage should i start him on? Is it safe to give it to him and > if so,> what dosage would you suggest for children under the age of 12?

 

> Yes, it is safe for kids to take Xango™. Kids love the taste and one > ounce a> day is also fine for them. I would suggest that they take it with > breakfast.

 

>

 

>

 

>

 

> 14.Do I have to order product every month?

 

> No you can order XanGo™ Juice whenever you need. There will be no > automatic> shipments made to you.

 

>

 

>

 

>

 

> 15.Has there been any study on the effects of Xango™ not only > killing bad> bacteria, but like many antibiotics, killing the good bacteria as > well?

 

> No studies have been done in humans about the antibiotic effects of> mangosteen extracts, only in Petri dishes in labs. However, the > folk> medicine in Thailand and Malaysia uses it to combat infectious > diarrhea> suggesting that it somehow acts only on pathogenic bacterial and > not> beneficial bowel flora. If this weren't the case it certainly > wouldn't be an> effective anti-diarrheal agent because it would cause and not cure > it.

 

>

 

> Read mangosteen benefits for diarrhea

 

>

 

> 16.What part of the mangosteen fruit is used for medicinal > purposes?

 

> The mangosteen fruit possesses the following three components: the > pericarp> (rind), seeds and pulp (sweet fruity part). Xanthones and > polysaccharides> (the medicinally active ingredients) are concentrated in the > pericarp of the> mangosteen fruit. The xanthones and polysaccharides are found in the > pulp> but in lower concentrations. For this reason, the pericarp is a > very> important part of the preparation.

 

>

 

>

 

>

 

> 17.What are Xanthones?

 

> Xanthones are a class of plant derived nutrients or > “phytonutrients.” They> have been demonstrated in numerous scientific studies to hold > tremendous> nutritional value. Found to exhibit strong antioxidant activity > xanthones> disarm free radicals in the body and enhance and support your body's > immune> system. Although xanthones exist in small amounts throughout nature, > it is> found in concentrated amounts in the pericarp of the mangosteen > fruit.

 

>

 

> There are over 20 known forms of xanthones naturally occurring in > the> pericarp, the two most widely studied are Alpha Mangostin and Gamma> Mangostin.

 

>

 

>

 

>

 

> 18.The pericarp or rind of the mangosteen is mostly made up of > fiber. I know> that fiber generally is just pushed through the digestive system > and> discarded along with waste. If most of the xanthones are found in > the> fiberous rind of the mangosteen, and the xango drink is just a > puree, how> can the body effectively absorb its medicinal properties?

 

> The xanthones that have been studied were extracted from the > pericarp in a> process somewhat analogous to digestion. The undigestible cellulose > of the> rind is of course not digested by the human GI tract and passes on > through> you. To render the chemically active substances available to the > body in the> most elementary way the fruit is simply pulped and the digestive > enzymes do> their thing to let the chemicals get across the gut wall to the > bloodstream.> The human body has no problem absorbing the nutrients from the > pericarp. In> fact, the process is identical to what happens to the greens you eat > that> are also more than 80% fiber as well.

 

>

 

>

 

>

 

> 19.If xanthones from mangosteen are so powerful, why haven't I heard > about> them?

 

> The people of Southeast Asia are very familiar with the prized > mangosteen> fruit and Asian Health Practitioners have long made use of pericarp > for a> myriad of nutritional uses. The mangosteen fruit, however, has never > been> introduced to the Western world and much of the science behind > xanthones is> predominantly available to those in the medical community until > recently.> Many of the clinical studies on xanthones have been done in > universities and> testing facilities throughout Asia and have recently started to > catch the> attention of Western researchers.

 

>

 

>

 

>

 

> 20.What is the most potent source of xanthones?

 

> According to the research, the most concentrated source of xanthones > found in nature is in the pericarp (rind) of the mangosteen fruit. > The majority of clinical studies on xanthones specify that the > xanthones used were from the mangosteen pericarp.> >

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Guest guest

Hello Pat,

 

Could you please remove the bible quotations from your emails to this group please? We don't allow a particular religious items in this group, as we have people of many faiths here.

 

And sorry I cannot answer your question as I know nothing of this item, but I'm sure someone else would have some info for you. Welcome to the group :-)

 

Thanks

 

Lisa de Haas

Senior Moderator

 

-

Bible Verses

herbal remedies

Tuesday, April 12, 2005 2:32 PM

Herbal Remedies - NEW MEMBER...MANGOSTEEN

My name is Pat and I live in Ontario. I have OA in my back, both hips, both knees, andboth ankles! grrrrrrrrrr. I have anklosing spondylitis of the back. I ordered some of thejuice from a man that came after me from a pain group and then a kind man named,Neil, told me I had been taken. The juice has already been paid for. Does anyone knowanything about this Mangosteen juice? Thanks for having me and God Bless, PatThe Lord bless you and keep you; the Lord make His faceto shine upon you, and be gracious to you; the Lord liftup His countenance upon you and give you peace.Numbers 6:24-26

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Guest guest

Pat,

Nice to meet you! Not too long ago there was a discussion about

mangosteen; I don't remember the particulars, as it's something new

to me, but if you search the archives you'll find it. You shouldn't

have to go too far back, it was maybe 2 months ago maximum.

 

Tracy in Ohio

 

 

herbal remedies , " Bible Verses "

<Bibleverses@h...> wrote:

>

> My name is Pat and I live in Ontario. I have OA in my back, both

hips, both

> knees, and

> both ankles! grrrrrrrrrr. I have anklosing spondylitis of the back.

I

> ordered some of the

> juice from a man that came after me from a pain group and then a

kind man

> named,

> Neil, told me I had been taken. The juice has already been paid

for. Does

> anyone know

> anything about this Mangosteen juice? Thanks for having me and God

Bless,

> Pat

>

>

>

> The Lord bless you and keep you; the Lord make His face

> to shine upon you, and be gracious to you; the Lord lift

> up His countenance upon you and give you peace.

> Numbers 6:24-26

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