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Ibogaine/Ibocaine

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anyone familiar with this plant based drug? Ibogaine was in recent

news being studied for addiction therapy--alcoholism, etc. It is

rumored to be the drug which cured eric clapton and one of the

rolling stones of their drug habits. Recent research determined that

this drug increases GDNF (glial derived neurotropic factor) which

was shown in a now aborted clinical trial to be life changing for

patients with late stage Parkinson's disease. the pharm co reason

for discontinuing the trial was that 2 of the experimental monkeys

developed suspicious brain lesions--something they knew prior to the

human clinical trials and had been dismissed as a result of giving

high doses of the drug and then precipitously withdrawing it--since

the drug was VERY difficult and EXPENSIVE to deliver, amgen dropped

the study --refused compassionate use and I have read, refused to

sell the patent to several of the university centers that banded

together and offered to purchase the patent. GDNF had to be

delivered thru catheters implanted in the brain, with a reservoir

for the drug implanted in the abdomen. Now seems there exists an

oral drug that can increase GDNF and several reserchers have

fractioned out the metabolites, losing the side effects of

hallucinations. The drug is banned in the US and Britian, though

clinics exist in St. Kitts (dr. deborah mash), Barcelona, Mexico,

Belgium.

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