KIDNEY STONES (Renal Calculi) AND THEIR RELATION TO DIET

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KIDNEY STONES (Renal Calculi) AND THEIR RELATION TO DIET

_http://www.doctoryourself.com/kidney.html_

(http://www.doctoryourself.com/kidney.html)

There are five types of kidney stones:

1. Calcium phosphate stones are common and easily dissolve in urine

acidified by vitamin C.

2. Calcium oxalate stones are also common but they do not dissolve in acid

urine.

3. Magnesium ammonium phosphate (struvite stones) are much less common,

often appearing after an infection. They dissolve in vitamin C acidified

urine.

 

4. Uric acid stones result from a problem metabolizing purines (the chemical

base of adenine, xanthine, theobromine [in chocolate] and uric acid). They

may form in a condition such as gout.

5. Cystine stones result from a hereditary inability to reabsorb cystine.

Most children's stones are this type, and these are rare.

The Role of Vitamin C in Preventing and Dissolving Kidney Stones:

The very common calcium phosphate stone can only exist in a urinary tract

that is not acidic. Ascorbic acid (vitamin C's most common form) acidifies the

urine, thereby dissolving phosphate stones and preventing their formation.

Acidic urine will also dissolve magnesium ammonium phosphate stones, which

would otherwise require surgical removal. These are the same struvite stones

associated with urinary tract infections. Both the infection and the stone are

easily cured with vitamin C in large doses. BOTH are virtually 100%

preventable with daily consumption of much-greater-than-RDA amounts of ascorbic

acid.

Think grams, not milligrams! A gorilla gets about 4,000 mg of vitamin C a

day in its natural diet. The US RDA for humans is only 60 mg. Someone is wrong,

and I don't think it's the gorillas.

The common calcium oxalate stone can form in an acidic urine whether one

takes vitamin C or not. However, if a person gets adequate quantities of

B-complex vitamins and magnesium, this type of stone does not form. Any common

B-complex supplement twice daily, plus about 400 milligrams of magnesium, is

usually adequate.

Ascorbate (the active ion in vitamin C) does increase the body's production

of oxalate. Yet, in practice, vitamin C does not increase oxalate stone

formation. Drs. Emanuel Cheraskin, Marshall Ringsdorf, Jr. and Emily Sisley

explain in The Vitamin C Connection (1983) that acidic urine or slightly acidic

urine reduces the UNION of calcium and oxalate, reducing the possibility of

stones. " Vitamin C in the urine tends to bind calcium and decrease its free

form. This means less chance of calcium's separating out as calcium oxalate

(stones). " (page 213) Also, the diuretic effect of vitamin C reduces the static

conditions necessary for stone formation in general. Fast moving rivers deposit

little silt.

Furthermore, you can avoid excessive oxalates by not eating (much) rhubarb,

spinach, or chocolate. If a doctor thinks that a person is especially prone

to forming oxalate stones, that person should read the suggestions below

before abandoning the benefits of vitamin C.

Robert F. Cathcart II, M.D. writes on **Why Don’t Massive Doses of Ascorbate

Produce Kidney Stones?**

**Years ago when Linus Pauling wrote his book " Vitamin C and the Common

Cold " , the critics immediately labeled the taking of large doses of vitamin C

dangerous because it would produce calcium oxalate kidney stones. This practice

of telling people that vitamin C caused kidney stones continues today by the

critics of vitamin C despite the lack of clinical evidence of kidney stones

in people taking vitamin C.

**It was hypothesized that since a significant percentage of ascorbate was

metabolized into and excreted as oxalic acid that this oxalic acid should

combine with calcium in the urine and deposit as calcium oxalate kidney stones.

It is true that those of us who take large doses of ascorbate have elevated

oxalic acid in our urine but no kidney stones. With the millions of people in

the world taking vitamin C, if vitamin C caused kidney stones there would have

been a massive epidemic of kidney stones noticed by this time. There has

been none.

**I started using vitamin C in massive doses in-patients in 1969. By the

time I read that ascorbate should cause kidney stones, I had clinical evidence

that it did not cause kidney stones, so I continued prescribing massive doses

to patients. To this day (2006) I estimate that I have put 25,000 patients on

massive doses of vitamin C and none have developed kidney stones. Two

patients who had dropped their doses to 500 mg a day developed calcium oxalate

kidney stones. I raised their doses back up to the more massive doses and added

magnesium and B6 to their program and no more kidney stones. I think that the

low doses had no effect and they, by coincidence, developed the kidney stones

because they were not taking enough vitamin C.â€**

(If you want to read more by Dr. Cathcart, a quick website search for

*Cathcart* from the _www.doctoryourself.com_ (http://www.doctoryourself.com/)

main

page will bring up a lot for you to look at.)

Ways for ANYONE to reduce the risk of kidney stones:

1. Maximize fluid intake. Especially drink fruit and vegetable juices.

Orange, grape and carrot juices are high in citrates which inhibit both a

build up of uric acid and also stop calcium salts from forming. (Carper, J.

" Orange Juice May Prevent Kidney Stones, " Lancaster Intelligencer-Journal, Jan

5,

1994)

2. Control urine pH: acidic urine helps prevent urinary tract infections,

dissolves both phosphate and struvite stones, and will not cause oxalate

stones.

3. Eat your veggies: studies have shown that dietary oxalate is generally

not a significant factor in stone formation. I would go easy on rhubarb and

spinach, however.

4. Most kidney stones are compounds of calcium and most Americans are

calcium deficient. Instead of lowering calcium intake, reduce excess dietary

phosphorous by avoiding carbonated soft drinks, especially colas. Soft drinks

contain excessive quantities of phosphorous as phosphoric acid. This is the

same

acid that has been used by dentists to etch tooth enamel before applying

sealant.

Remember that Americans get only about 500 mg of dietary calcium daily, and

the RDA is 800 to 1200 mg/day. Any nutritionist, doctor or text suggesting

calcium reduction is likely in error.

5. Take a magnesium supplement of AT LEAST the US RDA of 300-350 mg/day

(more may be desirable in order to maintain an ideal 1:2 balance of magnesium

to

calcium)

6. Be certain to take a good B-complex vitamin supplement daily, which

contains pyridoxine (vitamin B-6). B-6 deficiency produces kidney stones in

experimental animals. In high doses, it is also used medically to treat kidney

stones. Remember:

* B-6 deficiency is very common in humans

* B-1 (thiamine) deficiency also is associated with stones (Hagler and

Herman, " Oxalate Metabolism, II " American Journal of Clinical Nutrition, 26:8,

882-889, August, 1973)

7. Additionally, low calcium may itself CAUSE calcium stones (L. H. Smith,

et al, " Medical Evaluation of Urolithiasis " Urological Clinics of North

America 1:2, 241-260, June 1974)

8. For uric acid/purine stones (gout), STOP EATING MEAT! Nutrition tables

and textbooks indicate meats as the major dietary purine source. Naturopathic

treatment adds juice fasts and eating sour cherries. Increased vitamin C

consumption helps by improving the urinary excretion of uric acid. (Cheraskin,

et al, 1983). Use buffered ascorbate " C " .

9. Persons with cystine stones (only 1% of all kidney stones) should follow

a low methionine diet and use buffered C.

10. Kidney stones are associated with high sugar intake, so eat less (or

no) added sugar (J. A. Thom, et al " The Influence of Refined Carbohydrate on

Urinary Calcium Excretion, " British Journal of Urology, 50:7, 459-464,

December, 1978)

11. Infections can cause conditions that favor stone formation, such as

overly concentrated urine (from fever sweating, vomiting or diarrhea).

Practice

good preventive health care, and it will pay you back with interest.

 

REFERENCES:

Cheraskin, Ringsdorf Jr., and Sisley: The Vitamin C Connection, Harper and

Row, 1983

Pauling, Linus. " Are Kidney Stones Associated with Vitamin C Intake? "

Today's Living, September, 1981

Pauling, Linus. " Crystals in the Kidney, " Linus Pauling Institute

Newsletter, 1:11, Spring, 1981

Pauling, Linus. How to Live Longer and Feel Better, Freeman, 1986

VITAMIN C MYTH-BUSTERS

Is some clown still trying to tell you that vitamin C is somehow dangerous?

Or that you shouldn't take more than 200 mg/day? There is an excellent

summary article you will want to read at

_http://www.seanet.com/~alexs/ascorbate/misc/ascorbate-lies.htm_

(http://www.seanet.com/~alexs/ascorbate/misc/ascorbate-lies.htm)

And here's some more really good news for all you health nuts who every day

try so valiantly to convince friend, foe and family to take their vitamins:

VITAMIN C SAFETY STUDY

**Ascorbic Acid is a generally recognized as safe (GRAS) substance . . .

Mice given Ascorbic Acid subcutaneous and intravenous daily doses (500 to 1000

mg/kg bw) for 7 days had no changes in appetite, weight gain, and general

behavior; and histological examination of various organs showed no changes.

Ascorbic Acid was a photoprotectant when applied to mice and pig skin before

exposure to ultraviolet (UV) radiation. . . . Pregnant mice and rats were given

daily oral doses of Ascorbic Acid up to 1000 mg/kg bw with no indications of

adult-toxic, teratogenic, or fetotoxic effects. Ascorbic Acid and Sodium

Ascorbate were not genotoxic in several bacterial and mammalian test systems,

consistent with the antioxidant properties of these chemicals. . . These data

coupled with an absence of reports in the clinical literature of Ascorbic Acid

sensitization strongly support the safety of these ingredients.**

(Elmore AR. Final report of the safety assessment of L-Ascorbic Acid,

Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium

Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics. Int J Toxicol.

2005;24 Suppl 2:51-111.)

VITAMIN C DOES NOT CAUSE KIDNEY STONES

**The relation between the intake of vitamins B6 and C and the risk of

symptomatic kidney stones were prospectively studied in a cohort of 85,557

women

with no history of kidney stones. . . Large doses of vitamin B6 may reduce the

risk of kidney stone formation in women. Routine restriction of vitamin C to

prevent stone formation appears unwarranted.**

(Curhan, G. C., Willett, W. C., Speizer, F. E., Stampfer, M. J. Intake of

vitamins B6 and C and the risk of kidney stones in women. J Am Soc Nephrol

10:4:840-845, Apr 1999.)

VITAMIN C PREVENTS AND CURES RECTAL POLYPS

Jerome J. DeCosse, M.D., Ph.D., Mark B. Adams, M.D., Joseph F. Kuzma, M.D.,

Paul LoGerfo, M.D., and Robert E. Condon, M.D. Effect of ascorbic acid on

rectal polyps of patients with familial polyposis. Surgery, November, 1975,

Vol.

78, No. 5, pp. 608-612.

_http://www.seanet.com/~alexs/ascorbate/197x/decosse-jj-surgery-1975-v78-n5-p6

08.htm_

(http://www.seanet.com/~alexs/ascorbate/197x/decosse-jj-surgery-1975-v78-n5-p608\

..htm)

CARDIOVASCULAR DISEASE DECREASED BY VITAMIN C

**(T)here was a 27% decreased prevalence of coronary heart disease and a 26%

decreased prevalence of stroke among those in the highest serum vitamin C

category. In the NHANES I Epidemiologic Follow-up Study, it was found that the

highest intakes of vitamin C had a 25% to 50% reduction in cardiovascular

mortality.**

(Simon, JA et al. Serum ascorbic acid and cardiovascular disease prevalence

in U.S. adults. Epidemiology, 1998;9:316-321.)

 

 

 

Copyright C 2008, 2005 and prior years Andrew W. Saul.

Andrew Saul is the author of the books FIRE YOUR DOCTOR! How to be

Independently Healthy (reader reviews at

_http://www.doctoryourself.com/review.html_

(http://www.doctoryourself.com/review.html) ) and DOCTOR YOURSELF: Natural

Healing that Works. (reviewed at _http://www.doctoryourself.com/saulbooks.html_

(http://www.doctoryourself.com/saulbooks.html) )