Guest guest Posted January 26, 2010 Report Share Posted January 26, 2010 Common Conditions That May Result from Low Magnesium Levels _http://www.ctds.info/5_13_magnesium.html_ (http://www.ctds.info/5_13_magnesium.html) Magnesium (Mg) is a trace mineral that is known to be required for several hundred different functions in the body. A significant portion of the symptoms of many chronic disorders are identical to symptoms of magnesium deficiency. Studies show many people in the U.S. today do not consume the daily recommended amounts of Mg. A lack of this important nutrient may be a major factor in many common health problems in industrialized countries. Common conditions such as mitral valve prolapse, migraines, attention deficit disorder, fibromyalgia, asthma and allergies have all been linked to a Mg deficiency. Perhaps not coincidentally, these conditions also tend to occur in clusters together within the same individual. A magnesium deficiency as a root cause would provide a logical explanation of why some people suffer from a constellation of these types of problems. Many of the following conditions commonly occur in conjunction with each other and all have been linked to a Mg deficiency. Contents: _Allergies, Chemical Sensitivities_ (http://www.ctds.info/5_13_magnesium.html#magnesium_allergies) _Anxiety and Psychiatric Disorders_ (http://www.ctds.info/5_13_magnesium.html#anxiety) _Aorta Strength_ (http://www.ctds.info/5_13_magnesium.html#aorta) _Asthma_ (http://www.ctds.info/5_13_magnesium.html#magnesium_asthma) _Attention Deficit Disorder_ (http://www.ctds.info/5_13_magnesium.html#add) _Calcification of Soft Tissue Including Heart Valve_ (http://www.ctds.info/5_13_magnesium.html#calcification) _Diabetes_ (http://www.ctds.info/5_13_magnesium.html#diabetes) Also see: _Magnesium - Part Two_ (http://www.ctds.info/magnesium.html) - Covers the links between magnesium deficiency and diverse conditions such as fibromyalgia, hearing loss, migraines, menstrual cramps (dysmenorrhea), mitral valve prolapse, muscle cramps, nystagmus, osteoporosis, pectus excavatum, TMJ and more. Allergies and Chemical Sensitivities In the book Encyclopedia of Natural Medicine, the authors note that food allergies are usually associated with low hydrochloric acid levels and poor digestion. The authors' rationale for this is that low stomach acid leaves food undigested and fermenting in the intestinal tract. This fermentation causes gas, bloating and stomach upset, the symptoms of _irritable bowel syndrome_ (http://www.ctds.info/ibs_treatment.html) .. Undigested and fermented food causes the body to raise histamine levels, which produce allergic reactions. This is why people take antihistamines for allergies, to lower histamine levels. Interestingly, Mg is needed to reduce histamine levels. Low stomach acid levels reduce levels of beneficial intestinal bacteria which is needed for absorption of magnesium. When lab rats are deprived of magnesium, a wide variety of studies have noted that they develop _allergy like symptoms_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 7400981 & dopt=Abstract) . Their _ears turn red and they develop skin problems_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 7349544 & dopt=Abstract) . Rats with magnesium deficiencies have _ increases in histamine levels_ (http://www.ncbi.nlm.nih.gov/pubmed/3111814?dopt=Abstract) . They also have _raised levels of white blood cell counts_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 7349544 & dopt=Abstract) .. Mg deficiency has been implicated in allergies and allergic skin reaction in many studies on humans, too. Variations of allergies, skin allergies, and raised white blood cells have all been noted as features of many chronic disorders. People with chemical sensitivities also commonly have other conditions linked to Mg deficits such as allergies, fibromyalgia, mitral valve prolapse and anxiety disorders. They also tend to have _temporomandibular joint disorder (TMJ)_ (http://www.ctds.info/tmj.html) , which has been linked to abnormalities of _hyaluronic acid_ (http://www.ctds.info/hyaluronic_acid.html) . Perhaps not coincidentally, hyaluronic acid is dependent upon magnesium for its synthesis. Asthma is has been linked to Mg deficiencies in a wide variety of studies. Asthma and allergies not only frequently occur together, but they frequently occur together along with gastrointestinal upset in many chronic disorders including _Mitral Valve Prolapse _ (http://www.ctds.info/mvp1.html) syndrome and_ Ehlers-Danlos syndrome_ (http://www.ctds.info/eds.html) . Gastrointestinal upset is often a sign of malabsorption problems, which can be a cause of nutritional deficiencies. See my related section on _multiple chemical sensitivity_ (http://www.ctds.info/mcs.html) . Anxiety and Psychiatric Disorders Magnesium deficiency causes increased levels of adrenaline, which can lead to a feeling of anxiety. Rats who become magnesium deficient have an _ncreased level of urinary catecholamine_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 10454449 & dopt=Abstract) excretion (a by-product of adrenaline). People who have mitral valve prolapse have also been found to have an (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids= 6369371 & dopt=Abstract) increased state of anxiety and have an_ increased level of urinary catecholamine_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 6369371 & dopt=Abstract) excretion, the exact same condition found in rats who are Mg deficient. It is not surprising then, to find that people with _ mitral valve prolapse are usually low in magnesium_ (http://www.ncbi.nlm.nih.gov/pubmed/9070556?dopt=Abstract) , and that magnesium supplementation alleviates the symptoms of mitral valve prolapse and reduces the level of urinary catecholamine excretion, i.e. it also reduces the anxiety symptoms. Researchers in Spain found a correlation between _anxiety disorders and hypermobility_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 9812121 & dopt=Abstract) . In fact, they found that patients with anxiety disorder were over 16 times more likely than control subjects to have joint laxity. If you put the study results together, then there's a link between _anxiety and hypermobility_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 9812121 & dopt=Abstract) , a link between _anxiety and mitral valve prolapse_ (http://www.ncbi.nlm.nih.gov/pubmed/9070556?dopt=Abstract) , and a link between _mitral valve prolapse and hypermobility._ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 3409646 & dopt=Abstract) These studies tell us that anxiety disorders occur in many people who simply have mitral valve prolapse and/or joint hypermobility, meaning anxiety disorders are not specific to EDS or any particular connective tissue disorder. Marfans also have mitral valve prolapse and joint hypermobility which would lead one to conjecture that they, too, have anxiety related disorders. As it turns out, a connection between _Marfans and anxiety related disorders _ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 9068910 & dopt=Abstract) has been noted. A study in Bulgaria also found magnesium _abnormalities in patients with schizophrenia and depression_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 2077436 & dopt=Abstract) . The authors thought the schizophrenia and depression caused the magnesium deficiencies, but I disagree that that was necessarily the case. When you look at this study within the context of all the other studies mentioned in this section, it is more likely that the magnesium abnormalities caused the mental illness. (There are quite a few studies on magnesium and mental illness on Medline. I just included a few to highlight my points.) In a study from England, there was a strong association for _more disturbed and excitable patients to have abnormal (either high or low) Mg levels. _ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_u ids=7800167 & dopt=Abstract) The authors thought that the patients who seemed most disturbed may have some abnormality of magnesium metabolism. To read up on the link between cholesterol levels and anxiety and depression, see my web page on _low cholesterol levels_ (http://www.ctds.info/low_cholesterol.html) . For more on this topic, see my section on _Anxiety and Depression_ (http://www.ctds.info/anxiety_depression.html) - overlooked nutritional causes. Asthma _Magnesium sulfate_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 10622383 & dopt=Abstract) is used as a treatment for asthma. Mg is known to be important for _proper lung functioning._ (http://www.ncbi.nlm.nih.gov/pubmed/8509592?dopt=Abstract) Mg is being increasingly looked at as a treatment for asthma. A study from Brown University showed " remarkable " improvement in children with asthma who were treated with _intravenous magnesium_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 11030848 & dopt=A bstract) . Low polymorphonuclear magnesium content has been observed in patients with _bronchial asthma_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 7562826 & dopt=Abstract) . The study authors believe that polymorphonuclear magnesium content may have an important role in causing asthma. A study reported on in the Lancet, notes that people who have diets lower in Mg _have more asthmatic symptoms_ (http://www.ncbi.nlm ..nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=7914305 & dopt=Abstrac\ t) . People with diets higher in this important mineral have less asthmatic symptoms. Mg prevents _pre-asthmatic lung changes_ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 7701490 & dopt=Abstract) animal studies. Asthma is a common finding in connective tissue disorders, as are keratoconus, mitral valve prolapse, _rachitic skeletal defects_ (http://www.ctds.info/spinecurve.html) and many other conditions associated with magnesium deficiency. Asthma occurs frequently along with allergies, seizures and many other disorders that can all be linked to a Mg deficiency. Multivitamin tablets and pills often do not contain magnesium because it is a bulky mineral that makes the pill or tablets very large, so manufacturers often just leave it out! Yet multivitamin they contain many Mg antagonists, i.e. vitamins and minerals that lower magnesium levels in your body. Perhaps this is why _recent studies show that multivitamins usage is associated with asthma and allergies_ (http://www.aafp.org/afp/20050401/tips/14.html) . Click here to go to my diet page for _foods that have helped my breathing problems_ (http://www.ctds.info/ehlers_danlos_diet.html#variety) . Also see my _cool links_ (http://www.ctds.info/health_links.html) section for more information on asthma. Calcification Of Soft Tissue Including Heart Valves Magnesium is a known treatment for a variety of types of_ calcification of soft tissues._ (http://www.ncbi.nlm.nih.gov/pubmed/2133625?dopt=Abstract) Mg levels have been found to be greatly reduced _ in calcified mitral valves._ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 3199134 & dopt=Abstract) In a study of rats, Mg deficiency has been shown to cause _aortic calcification._ (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=\ 8948519 & dopt=Abstract) _Vitamin K deficiency _ (http://www.ctds.info/vitamink.html#symptoms) has also been linked to calcification of soft tissues. Also see my section on _Calcium Deposits. _ (http://www.ctds.info/calcium-deposits.html) Diabetes A _2005 landmark study_ (http://www.thecrimson.com/article.aspx?ref=357095) by researchers from the Harvard School of Public found an inverse association between type 2 diabetes and magnesium intake. The major recommendation from this study was for people to consume more magnesium rich foods. For more on this topic see my sections on _fibromyalgia and diabetes_ (http://www.ctds.info/diabetes.html) and _diabetic frozen shoulder_ (http://www.ctds.info/diabetic.html) . Continued at Magnesium - _Part Two_ (http://www.ctds.info/magnesium.html) Quote Link to comment Share on other sites More sharing options...
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