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No Garlic/Onions for Dogs

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This is why we don't worm with garlic (or alliums). Personally we usesunflower seed,cloves,and DE. Using garlic or other alliums is toxic todogs and cats. Giving repeated daily doses or even 1 large dose can befatal.Old remedies are good when combined with present day knowledge. That's whyarticles are very important and relevant instead of first hand experience.I always say a little knowledge is a dangerous thing. And so is pickingand choosing what you "like" or "hear" instead of doing the research foryourself. Don't play the blame game-do your homework,get opinions andfacts,and use your head!!As my folks used to say-"that's why you're given abrain-use it!"BarbToxicology Brief: Allium species poisoning in dogs and catsAug 1, 2005By: R.B. Cope, BSc, BVSc, PhDVETERINARY MEDICINEWild and domesticated Allium species have been used for culinary andethnomedicinal purposes since the beginning of recorded history. About 95species of native or cultivated leeks, chives, garlic, shallots, scallions,and onions are present in North America, and more than 80 ornamental Alliumspecies are available. All Allium species and the products derived fromthem can be toxic to dogs and cats1; however, relatively few Allium speciesare of important toxicologic interest.The domesticated species commonly involved in toxicosis include Allium cepa(onion), Allium porrum (leek), Allium sativum (garlic), and Alliumschoenoprasum (chive). The plants form solitary or clustered bulbs and arestrongly aromatic, with an onion or garlic odor when crushed. Thedistinctive aroma distinguishes Allium species from morphologically similarpoisonous plants, particularly death camas (Zigadenus species).1ToxicityAllium species contain a wide variety of organosulfoxides, particularlyalk(en)ylcysteine sulfoxides. Trauma to the plants, such as chewing,converts the organosulfoxides to a complex mixture of sulfur-containingorganic compounds. Many of these compounds or their metabolites areresponsible for the odors, flavors, and pharmacologic effects of theseplants. Many Allium species' organosulfur compounds appear to be readilyabsorbed through the gastrointestinal tract and are metabolized to highlyreactive oxidants.2 Cooking or spoilage of Allium species does not reducetheir potential toxicity.1Mechanism of actionThe primary toxicologic mechanism of Allium species-derived organosulfurcompounds is oxidative hemolysis, which occurs when the concentration ofoxidants in the erythrocyte exceeds the capacity of the antioxidantmetabolic pathways. Catalase antioxidant activity in erythrocytes in dogsis low,3 and normal hemoglobin in cats is about two to three times moresusceptible to oxidative damage than the hemoglobin in other species.4Oxidation of the exposed beta-93 cysteine residues present in hemoglobinresults in the formation of sulfhemoglobin.5 Sulfhemoglobin is less solublethan hemoglobin, so it precipitates, aggregates, and binds to the cellmembrane and forms Heinz bodies. Other types of oxidation of hemoglobinglobin chains result in membrane cross-linking reactions and eccentrocyteformation.6 The formation of Heinz bodies and eccentrocytes increaseserythrocyte fragility and extravascular hemolysis. Direct oxidative damageto the erythrocyte cell membrane and its sodium-potassium pump or theoxidative production of hemin also contributes to cell lysis. Oxidation ofthe heme ion and associated methemoglobinemia results in a left shift ofthe hemoglobin-oxygen dissociation curve, decreased blood oxygentransportation capacity, and, ultimately, impaired delivery of oxygen tothe tissues.Thus, the result of the oxidative hemolytic process induced by Alliumspecies consumption is the onset of anemia, methemoglobinemia, and impairedoxygen transportation. Although marked Heinz body formation may be presentwithin a day after onions are ingested, the anemic nadir typically developsseveral days later.Allicin and ajoene, pharmacologically active agents in garlic, are potentcardiac and smooth muscle relaxants, vasodilators, and hypotensiveagents.7-9 Also, ajoene and other organosulfur compounds derived fromonions are potent antithrombotic agents.10 Thus, hypotensive andantithrombotic effects can exacerbate the physiologic effects of anemia andimpaired oxygen transportation. Garlic preparations that have not been agedcause direct damage to the gastric and ileal mucosa, resulting in pain anddiarrhea.11Exposure and susceptibilityAllium species toxicosis most commonly occurs after oral consumption. Inaddition to consuming fresh plant material, consuming juice, fresh and ageddietary supplements, powdered cooking preparations, dehydrated material, orfood preparations derived from or containing Allium species can bepotentially toxic to dogs and cats.1Allium species toxicosis typicallyensues after consumption of a single large quantity of the material orrepeated small amounts. Dogs and cats are highly susceptible to oniontoxicosis: Consumption of as little as 5 g/kg of onions in cats or 15 to 30g/kg in dogs has resulted in clinically important hematologic changes.Onion toxicosis is consistently noted in animals that ingest more than 0.5%of their body weight in onions at one time. Pages | 1 | 2 | 3morehttp://veterinarymedicine.dvm360.com/vetmed/Medicine/Toxicology-Brief-iAlliumi-species-poisoning-in-dog/ArticleStandard/Article/detail/174478Onion and garlic poisoning TopOnions and garlic are other dangerous food ingredients that cause sicknessin dogs, cats and also livestock. Onions and garlic contain the toxicingredient thiosulphate. Onions are more of a danger.Pets affected by onion toxicity will develop haemolytic anaemia, where thepet’s red blood cells burst while circulating in its body.At first, pets affected by onion poisoning show gastroenteritis withvomiting and diarrhoea. They will show no interest in food and will be dulland weak. The red pigment from the burst blood cells appears in an affectedanimal’s urine and it becomes breathless. The breathlessness occursbecause the red blood cells that carry oxygen through the body are reducedin number.The poisoning occurs a few days after the pet has eaten the onion. Allforms of onion can be a problem including dehydrated onions, raw onions,cooked onions and table scraps containing cooked onions and/or garlic. Leftover pizza, Chinese dishes and commercial baby food containing onion,sometimes fed as a supplement to young pets, can cause illness.Onion poisoning can occur with a single ingestion of large quantities orwith repeated meals containing small amounts of onion. A single meal of 600to 800 grams of raw onion can be dangerous whereas a ten-kilogram dog, fed150 grams of onion for several days, is also likely to develop anaemia. Thecondition improves once the dog is prevented from eating any further onionWhile garlic also contains the toxic ingredient thiosulphate, it seems thatgarlic is less toxic and large amounts would need to be eaten to causeillness.http://www.petalia.com.au/templates/storytemplate_process.cfm?specie=dogs & story_no=257

 

 

 

 

 

 

 

 

 

 

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