Causal Relationship Between Vaccines and Diabetes - Proof that the hemophilus vaccine causes diabetes

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http://www.vaccines.net/newpage16.htm

Hemophilus Vaccine Study in Finland Proves a Causal Relationship Between Vaccines and Diabetes

(published Autoimmunity 35:247-253,2002)

 

Dr. J. Bart Classen discovered it would be possible to study the effect of Hemophilus B immunization on the incidence of IDDM using data from a large clinical trial in Finland. Dr. J. Bart Classen and D.C. Classen initiated and funded a collaboration with Dr. Tuomilehto in Finland. All children born in Finland between October 1st, 1985 and August 31st, 1987, approximately 116,000 were randomized to receive 4 doses of the HiB vaccine (PPR-D, Connaught) starting at 3 months of life or one dose starting at 24 months of life. Classen and Classen calculated the incidence of IDDM in both groups through age 10 and in an group which did not receive the HiB vaccine, a cohort which included all 128,500 children born in Finland in the 24 months prior to the Hemophilus vaccine study. Immediately following the completion of these two arms all children born in Finland over a two year period were randomized to receive 3 doses of the old PPR-D HiB vaccine or 3 doses of a newer HbOC HiB vaccine. The data supports published findings that the immunization starting after 2 months of life is associated with an increased incidence of IDDM. Rises in diabetes have been seen in the UK and USA following the introduction of the hemophilus vaccine (see HIB)

Proof that the hemophilus vaccine causes diabetes is summarized in the graphs and tables below. Data from the clinical trial (Figures 1 A and 1B) shows distinct clusters of diabetes caused by the hemophilus vaccine. The cases of diabetes caused by the vaccine occur in clusters starting approximately 38 months after immunization and lasting approximately 6-8 months. In these time frames the relative risk exceeds 2, meaning that the majority of cases of diabetes are caused by the vaccine. The clustering effect in the graphs below is very significant since the delay between immunization and the development of diabetes is identical to the delay reported by several independent groups between the detection of autoantibodies to insulin secreting pancreatic islet cells and the development of diabetes (see Journal of Pediatric Endocrinology and Metabolism 16 (4):495-507, 2003)

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Further support for a causal relationship is demonstrated in Figures 2 and 3 below. Figure 2 shows the incidence of diabetes in the underlying population in Finland had been stable in the 5-9 year old population but rose after routine hemophilus immunization in a predictable manner based on the clinical trial. Figure 3 shows the hemophilus vaccine causes diabetes in mice.

[see graphs on site]