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Does anybody know of a good website that would contain scientific papers

regarding this " successful " research from China? Where I am located right

now I am unable to get to a TCM school library and so the web is my only

option.

In obtaining my B.S. in biology I must give several seminars on a topic of

my choice; the only requirement being that it is a scientific paper from

a peer reviewed journal. Last semester I gave a talk on a specific plant

protein isolated from Momordica charantia (I don't know it's chinese name,

it is also known as bitter melon) which was utilized to inactivate the HIV

virus.

I would prefer to give my next talk on a paper that is based on an herbal

formula. This is one of the problems with convincing the scientific

world in the use of herbal medicines. They look for isolated chemicals or

proteins,etc... while a formula containing up to 15 different herbs would

be boggling to the reductionists mind in ascertaining what actually caused

the effect.

There is even talk out there that the Wesern herbalists remedy

for such scepticism, standardized extracts, do not actually have the amount

of standardization they claim to have.

 

If anyone has some leads on sites or places I could write away to, to

obtain these papers I would be very interested!

Thanks,

David

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Dear David,

I am not aware of any websites that have the information in English. .

.. .The actual journals can be obtained via mail from Eastwind Books, (415)

772-5899 in San Francisco. . .while in Chinese, there are English abstracts

accompanying them. Also, Blue Poppy Press in Boulder, Colo. translates

this research (1-800-487-9296), and has many articles available of this

type.

 

I recently had a meeting with Novartis Research scientists, who would

like to do studies on Chinese herbs. . . .but they again want isolated

extracts to use in mice or test-tube situations. . ..they simply have no

model for examining complex prescriptions at this point. This is a big

problem.

 

For example, Compound Q, the momordica extract you mentioned (tian hua

fen, or trichosanthes root), was used in actual trials and underground in

the HIV community, but was found to be toxic to the nervous system, causing

convulsions, etc. No such effects are found when the herb itself is taken.

 

 

Standardized extracts are another problem. Many herb companies have

standardized their extracts in terms of amounts of herbal material, but

only German companies, as far as I know, have standardized the actual

'active' chemical constituents. . . .usually by refining out other

components.

 

, FNAAOM

 

 

 

 

>dcrussell

>

>Does anybody know of a good website that would contain scientific papers

>regarding this " successful " research from China? Where I am located right

>now I am unable to get to a TCM school library and so the web is my only

>option.

>In obtaining my B.S. in biology I must give several seminars on a topic of

>my choice; the only requirement being that it is a scientific paper from

>a peer reviewed journal. Last semester I gave a talk on a specific plant

>protein isolated from Momordica charantia (I don't know it's chinese name,

>it is also known as bitter melon) which was utilized to inactivate the HIV

>virus.

>I would prefer to give my next talk on a paper that is based on an herbal

>formula. This is one of the problems with convincing the scientific

>world in the use of herbal medicines. They look for isolated chemicals or

>proteins,etc... while a formula containing up to 15 different herbs would

>be boggling to the reductionists mind in ascertaining what actually caused

>the effect.

>There is even talk out there that the Wesern herbalists remedy

>for such scepticism, standardized extracts, do not actually have the amount

>of standardization they claim to have.

>

>If anyone has some leads on sites or places I could write away to, to

>obtain these papers I would be very interested!

>Thanks,

>David

>

>--------------------------- ONElist Sponsor ----------------------------

>

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>For details and to order, go to:

><a href= " http://clickme./ad/tshirt1 " >Click Here</a>

>

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Dave,

 

Unfortunately most of it is not in english. However, subhuti

dharmananda has been summarizing translations and abstracts of this info

for twenty years. Contact him at itmonline.org. Blue poppy has a whole

series of translated research reports, request their catalog at

www.bluepoppy.com

 

Does anyone have an opinion on the controversy over whether chinese

herbs should be restricted to TCM style practice or expanded to

allopathic use, as well.

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A word about standardized extracts as there is no standard definition of

this term and a lot of misinformation out there right now. First,

standardization simply means that a product has been concentrated to

yield a specific level of a " marker " ingredient in the final product.

No reputable company that I am aware of considers this marker to be the

sole or even the most important constituent of the herb. In fact, all

herb companies make a point of saying that their product is a

synergistic blend of components, not an isolated component. So while it

is true that only large companies have the technology to standardize a

product, it is totally untrue that the typical product from Germany are

essentially drugs that have had most of their normal consitutents

refined away.

 

In fact, the typical standardized extract has a full complement of

constituents, while most nonstandardized extracts have little or nothing

in them at all. For example, standardized st john's wort from nature's

plus contains dozens of constituents, which is documented by laboratory

analysis. Not only does it contain .3% hypericin, but everything else

in proportion, as well. Comparison products made " naturally " have been

shown to contain 50 times less of everything, making them essentially

worthless.

 

Standardization guarantees potency and reproducibility in dosage, which

is a critical problem in mainstreaming herbology. German companies

manipulate concentration levels to comply with their federal law which

is geared towrds safe and effective dosage. It would actually cost them

more to refine these herbs or " spike " them with drugs or isolates as is

so often insinuated. There are certainly issues of solvents, toxic

waste, ecology and corporatism surrounding these products, but these

have nothing to do with standardization, per se. We need to focus on

these real concerns.

 

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Todd is correct.

I should not have stated 'refined out' other constituents. . . .I should

have said tried to standardize the dosage level. I wasn't thinking clearly

at the time, I guess.

 

Z'ev

 

 

 

 

 

>A word about standardized extracts as there is no standard definition of

>this term and a lot of misinformation out there right now. First,

>standardization simply means that a product has been concentrated to

>yield a specific level of a " marker " ingredient in the final product.

>No reputable company that I am aware of considers this marker to be the

>sole or even the most important constituent of the herb. In fact, all

>herb companies make a point of saying that their product is a

>synergistic blend of components, not an isolated component. So while it

>is true that only large companies have the technology to standardize a

>product, it is totally untrue that the typical product from Germany are

>essentially drugs that have had most of their normal consitutents

>refined away.

>

>In fact, the typical standardized extract has a full complement of

>constituents, while most nonstandardized extracts have little or nothing

>in them at all. For example, standardized st john's wort from nature's

>plus contains dozens of constituents, which is documented by laboratory

>analysis. Not only does it contain .3% hypericin, but everything else

>in proportion, as well. Comparison products made " naturally " have been

>shown to contain 50 times less of everything, making them essentially

>worthless.

>

>Standardization guarantees potency and reproducibility in dosage, which

>is a critical problem in mainstreaming herbology. German companies

>manipulate concentration levels to comply with their federal law which

>is geared towrds safe and effective dosage. It would actually cost them

>more to refine these herbs or " spike " them with drugs or isolates as is

>so often insinuated. There are certainly issues of solvents, toxic

>waste, ecology and corporatism surrounding these products, but these

>have nothing to do with standardization, per se. We need to focus on

>these real concerns.

>

>Todd

>

>

>Received: from mailsorter-102-1.iap.bryant.webtv.net (209.240.198.98) by

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>In-<936380901.11822 >

>Fri, 3 Sep 1999 12:59:27 -0700

>

> " " <zrosenberg

>Mailing-List: list ; contact

> -owner

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>List-Un: <- (AT) ONElist (DOT) com>

>Reply-to:

>Mime-Version: 1.0

>Content-Type: text/plain; charset= " us-ascii "

>Re: herbal research

>

> " " <zrosenberg

>

>Dear David,

> I am not aware of any websites that have the information in English. .

>. .The actual journals can be obtained via mail from Eastwind Books, (415)

>772-5899 in San Francisco. . .while in Chinese, there are English abstracts

>accompanying them. Also, Blue Poppy Press in Boulder, Colo. translates

>this research (1-800-487-9296), and has many articles available of this

>type.

>

> I recently had a meeting with Novartis Research scientists, who would

>like to do studies on Chinese herbs. . . .but they again want isolated

>extracts to use in mice or test-tube situations. . ..they simply have no

>model for examining complex prescriptions at this point. This is a big

>problem.

>

> For example, Compound Q, the momordica extract you mentioned (tian hua

>fen, or trichosanthes root), was used in actual trials and underground in

>the HIV community, but was found to be toxic to the nervous system, causing

>convulsions, etc. No such effects are found when the herb itself is taken.

>

>

> Standardized extracts are another problem. Many herb companies have

>standardized their extracts in terms of amounts of herbal material, but

>only German companies, as far as I know, have standardized the actual

>'active' chemical constituents. . . .usually by refining out other

>components.

>

>, FNAAOM

>

>

>

>

>>dcrussell

>>

>>Does anybody know of a good website that would contain scientific papers

>>regarding this " successful " research from China? Where I am located right

>>now I am unable to get to a TCM school library and so the web is my only

>>option.

>>In obtaining my B.S. in biology I must give several seminars on a topic of

>>my choice; the only requirement being that it is a scientific paper from

>>a peer reviewed journal. Last semester I gave a talk on a specific plant

>>protein isolated from Momordica charantia (I don't know it's chinese name,

>>it is also known as bitter melon) which was utilized to inactivate the HIV

>>virus.

>>I would prefer to give my next talk on a paper that is based on an herbal

>>formula. This is one of the problems with convincing the scientific

>>world in the use of herbal medicines. They look for isolated chemicals or

>>proteins,etc... while a formula containing up to 15 different herbs would

>>be boggling to the reductionists mind in ascertaining what actually caused

>>the effect.

>>There is even talk out there that the Wesern herbalists remedy

>>for such scepticism, standardized extracts, do not actually have the amount

>>of standardization they claim to have.

>>

>>If anyone has some leads on sites or places I could write away to, to

>>obtain these papers I would be very interested!

>>Thanks,

>>David

>>

>>--------------------------- ONElist Sponsor ----------------------------

>>

>>ONElist now has T-SHIRTS!

>>For details and to order, go to:

>><a href= " http://clickme./ad/tshirt1 " >Click Here</a>

>>

>>------

>>Chronic Diseases Heal - Chinese Herbs Can Help

>

>

>

>

>--------------------------- ONElist Sponsor ----------------------------

>

>ONElist: your connection to online communities.

>

>------

>Chronic Diseases Heal - Chinese Herbs Can Help

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Another reply. . .

A better example would be a Chinese one. . . .corydalin, a crude drug

supposedly refined from yan hu suo/rz. corydalis to a 'pure' drug

containing the active ingredient. How safe, toxic or reliable this

substance is is anyone's guess.

 

 

 

 

 

>A word about standardized extracts as there is no standard definition of

>this term and a lot of misinformation out there right now. First,

>standardization simply means that a product has been concentrated to

>yield a specific level of a " marker " ingredient in the final product.

>No reputable company that I am aware of considers this marker to be the

>sole or even the most important constituent of the herb. In fact, all

>herb companies make a point of saying that their product is a

>synergistic blend of components, not an isolated component. So while it

>is true that only large companies have the technology to standardize a

>product, it is totally untrue that the typical product from Germany are

>essentially drugs that have had most of their normal consitutents

>refined away.

>

>In fact, the typical standardized extract has a full complement of

>constituents, while most nonstandardized extracts have little or nothing

>in them at all. For example, standardized st john's wort from nature's

>plus contains dozens of constituents, which is documented by laboratory

>analysis. Not only does it contain .3% hypericin, but everything else

>in proportion, as well. Comparison products made " naturally " have been

>shown to contain 50 times less of everything, making them essentially

>worthless.

>

>Standardization guarantees potency and reproducibility in dosage, which

>is a critical problem in mainstreaming herbology. German companies

>manipulate concentration levels to comply with their federal law which

>is geared towrds safe and effective dosage. It would actually cost them

>more to refine these herbs or " spike " them with drugs or isolates as is

>so often insinuated. There are certainly issues of solvents, toxic

>waste, ecology and corporatism surrounding these products, but these

>have nothing to do with standardization, per se. We need to focus on

>these real concerns.

>

>Todd

>

>

>Received: from mailsorter-102-1.iap.bryant.webtv.net (209.240.198.98) by

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>In-<936380901.11822 >

>Fri, 3 Sep 1999 12:59:27 -0700

>

> " " <zrosenberg

>Mailing-List: list ; contact

> -owner

>Delivered-mailing list

>Precedence: bulk

>List-Un: <- (AT) ONElist (DOT) com>

>Reply-to:

>Mime-Version: 1.0

>Content-Type: text/plain; charset= " us-ascii "

>Re: herbal research

>

> " " <zrosenberg

>

>Dear David,

> I am not aware of any websites that have the information in English. .

>. .The actual journals can be obtained via mail from Eastwind Books, (415)

>772-5899 in San Francisco. . .while in Chinese, there are English abstracts

>accompanying them. Also, Blue Poppy Press in Boulder, Colo. translates

>this research (1-800-487-9296), and has many articles available of this

>type.

>

> I recently had a meeting with Novartis Research scientists, who would

>like to do studies on Chinese herbs. . . .but they again want isolated

>extracts to use in mice or test-tube situations. . ..they simply have no

>model for examining complex prescriptions at this point. This is a big

>problem.

>

> For example, Compound Q, the momordica extract you mentioned (tian hua

>fen, or trichosanthes root), was used in actual trials and underground in

>the HIV community, but was found to be toxic to the nervous system, causing

>convulsions, etc. No such effects are found when the herb itself is taken.

>

>

> Standardized extracts are another problem. Many herb companies have

>standardized their extracts in terms of amounts of herbal material, but

>only German companies, as far as I know, have standardized the actual

>'active' chemical constituents. . . .usually by refining out other

>components.

>

>, FNAAOM

>

>

>

>

>>dcrussell

>>

>>Does anybody know of a good website that would contain scientific papers

>>regarding this " successful " research from China? Where I am located right

>>now I am unable to get to a TCM school library and so the web is my only

>>option.

>>In obtaining my B.S. in biology I must give several seminars on a topic of

>>my choice; the only requirement being that it is a scientific paper from

>>a peer reviewed journal. Last semester I gave a talk on a specific plant

>>protein isolated from Momordica charantia (I don't know it's chinese name,

>>it is also known as bitter melon) which was utilized to inactivate the HIV

>>virus.

>>I would prefer to give my next talk on a paper that is based on an herbal

>>formula. This is one of the problems with convincing the scientific

>>world in the use of herbal medicines. They look for isolated chemicals or

>>proteins,etc... while a formula containing up to 15 different herbs would

>>be boggling to the reductionists mind in ascertaining what actually caused

>>the effect.

>>There is even talk out there that the Wesern herbalists remedy

>>for such scepticism, standardized extracts, do not actually have the amount

>>of standardization they claim to have.

>>

>>If anyone has some leads on sites or places I could write away to, to

>>obtain these papers I would be very interested!

>>Thanks,

>>David

>>

>>--------------------------- ONElist Sponsor ----------------------------

>>

>>ONElist now has T-SHIRTS!

>>For details and to order, go to:

>><a href= " http://clickme./ad/tshirt1 " >Click Here</a>

>>

>>------

>>Chronic Diseases Heal - Chinese Herbs Can Help

>

>

>

>

>--------------------------- ONElist Sponsor ----------------------------

>

>ONElist: your connection to online communities.

>

>------

>Chronic Diseases Heal - Chinese Herbs Can Help

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Let's be sure we are talking about the same thing, here. A standardized

extract is not the same as an isolate or fraction. Isolates or

fractions are similar or identical to drugs, many of which are still

derived directly from plants. So corydalin is definitely a drug with

inherent safety risks, but standardized corydalis is is a full spectrum

herb with a guaranteed level of corydalin. This allows you to know that

one dose of corydalis extract will have a similar potency to the next

and so on. But it is not an isolate and has no greater risk of side

effects than the crude herb.

 

If one prefers to use bulk herbs and one has some expertise in the area

of herb evaluation, you can control the qualtiy of your prescription by

selecting only fresh looking, properly colored, not moldy, potent

smelling ingredients. But what if you do not fill your own formulae, or

order yourown bulk herbs or rely on a cokpany to do this process for

you. How do you know who to trust? KPC granules doesn't standardize

their products, but they test all batches for minimum levels of active

ingredients. Without this assurance, how could I know if the herbs were

of good quality? Correct standardization of whole herbs, not isolation

of drugs, is an actually an important issue for the whole herbal

industry to consider. Anythng less is irresponsible to our patients,

unless each herbalist is also a fully trained herbal pharmacist and uses

only bulk herbs.

 

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I agree on the issues of dosage standardization.

 

Corydalin is an isolate, not an herbal extract, making it technically a drug.

 

 

 

 

 

>Let's be sure we are talking about the same thing, here. A standardized

>extract is not the same as an isolate or fraction. Isolates or

>fractions are similar or identical to drugs, many of which are still

>derived directly from plants. So corydalin is definitely a drug with

>inherent safety risks, but standardized corydalis is is a full spectrum

>herb with a guaranteed level of corydalin. This allows you to know that

>one dose of corydalis extract will have a similar potency to the next

>and so on. But it is not an isolate and has no greater risk of side

>effects than the crude herb.

>

>If one prefers to use bulk herbs and one has some expertise in the area

>of herb evaluation, you can control the qualtiy of your prescription by

>selecting only fresh looking, properly colored, not moldy, potent

>smelling ingredients. But what if you do not fill your own formulae, or

>order yourown bulk herbs or rely on a cokpany to do this process for

>you. How do you know who to trust? KPC granules doesn't standardize

>their products, but they test all batches for minimum levels of active

>ingredients. Without this assurance, how could I know if the herbs were

>of good quality? Correct standardization of whole herbs, not isolation

>of drugs, is an actually an important issue for the whole herbal

>industry to consider. Anythng less is irresponsible to our patients,

>unless each herbalist is also a fully trained herbal pharmacist and uses

>only bulk herbs.

>

>Todd

>

>

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>References: " " <zrosenberg's message of

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>Sat, 4 Sep 1999 20:14:26 -0700

>

> " " <zrosenberg

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>Reply-to:

>Mime-Version: 1.0

>Content-Type: text/plain; charset= " us-ascii "

>Re: herbal research

>

> " " <zrosenberg

>

>Another reply. . .

>A better example would be a Chinese one. . . .corydalin, a crude drug

>supposedly refined from yan hu suo/rz. corydalis to a 'pure' drug

>containing the active ingredient. How safe, toxic or reliable this

>substance is is anyone's guess.

>

>

>

>

>

>>A word about standardized extracts as there is no standard definition of

>>this term and a lot of misinformation out there right now. First,

>>standardization simply means that a product has been concentrated to

>>yield a specific level of a " marker " ingredient in the final product.

>>No reputable company that I am aware of considers this marker to be the

>>sole or even the most important constituent of the herb. In fact, all

>>herb companies make a point of saying that their product is a

>>synergistic blend of components, not an isolated component. So while it

>>is true that only large companies have the technology to standardize a

>>product, it is totally untrue that the typical product from Germany are

>>essentially drugs that have had most of their normal consitutents

>>refined away.

>>

>>In fact, the typical standardized extract has a full complement of

>>constituents, while most nonstandardized extracts have little or nothing

>>in them at all. For example, standardized st john's wort from nature's

>>plus contains dozens of constituents, which is documented by laboratory

>>analysis. Not only does it contain .3% hypericin, but everything else

>>in proportion, as well. Comparison products made " naturally " have been

>>shown to contain 50 times less of everything, making them essentially

>>worthless.

>>

>>Standardization guarantees potency and reproducibility in dosage, which

>>is a critical problem in mainstreaming herbology. German companies

>>manipulate concentration levels to comply with their federal law which

>>is geared towrds safe and effective dosage. It would actually cost them

>>more to refine these herbs or " spike " them with drugs or isolates as is

>>so often insinuated. There are certainly issues of solvents, toxic

>>waste, ecology and corporatism surrounding these products, but these

>>have nothing to do with standardization, per se. We need to focus on

>>these real concerns.

>>

>>Todd

>>

>>

>>Received: from mailsorter-102-1.iap.bryant.webtv.net (209.240.198.98) by

>> postoffice-241.iap.bryant.webtv.net with WTV-SMTP; Fri, 3 Sep 1999

>> 13:01:27 -0700 (PDT)

>>Return-Path: <errors-201013-40-TLuger=webtv.net >

>>Received: from (pop. [209.207.164.211]) by

>> mailsorter-102-1.iap.bryant.webtv.net (8.8.8/ms.graham.14Aug97)

>> with SMTP id NAA08996 for <TLuger; Fri, 3 Sep 1999

>> 13:01:25 -0700 (PDT)

>>Received: (qmail 32385 invoked by alias); 3 Sep 1999 20:01:49 -0000

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>> pop. with SMTP; 3 Sep 1999 20:01:48 -0000

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>> [209.209.65.197]) by smtp.inreach.com (8.9.3/8.9.3) with ESMTP id

>> MAA29319 for < >; Fri, 3 Sep 1999

>> 12:46:09 -0700 (PDT)

>>Message-Id: <v03007803b3f5d74d297c@[209.209.65.62]>

>>In-<936380901.11822 >

>>Fri, 3 Sep 1999 12:59:27 -0700

>>

>> " " <zrosenberg

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>>Re: herbal research

>>

>> " " <zrosenberg

>>

>>Dear David,

>> I am not aware of any websites that have the information in English. .

>>. .The actual journals can be obtained via mail from Eastwind Books, (415)

>>772-5899 in San Francisco. . .while in Chinese, there are English abstracts

>>accompanying them. Also, Blue Poppy Press in Boulder, Colo. translates

>>this research (1-800-487-9296), and has many articles available of this

>>type.

>>

>> I recently had a meeting with Novartis Research scientists, who would

>>like to do studies on Chinese herbs. . . .but they again want isolated

>>extracts to use in mice or test-tube situations. . ..they simply have no

>>model for examining complex prescriptions at this point. This is a big

>>problem.

>>

>> For example, Compound Q, the momordica extract you mentioned (tian hua

>>fen, or trichosanthes root), was used in actual trials and underground in

>>the HIV community, but was found to be toxic to the nervous system, causing

>>convulsions, etc. No such effects are found when the herb itself is taken.

>>

>>

>> Standardized extracts are another problem. Many herb companies have

>>standardized their extracts in terms of amounts of herbal material, but

>>only German companies, as far as I know, have standardized the actual

>>'active' chemical constituents. . . .usually by refining out other

>>components.

>>

>>, FNAAOM

>>

>>

>>

>>

>>>dcrussell

>>>

>>>Does anybody know of a good website that would contain scientific papers

>>>regarding this " successful " research from China? Where I am located right

>>>now I am unable to get to a TCM school library and so the web is my only

>>>option.

>>>In obtaining my B.S. in biology I must give several seminars on a topic of

>>>my choice; the only requirement being that it is a scientific paper from

>>>a peer reviewed journal. Last semester I gave a talk on a specific plant

>>>protein isolated from Momordica charantia (I don't know it's chinese name,

>>>it is also known as bitter melon) which was utilized to inactivate the HIV

>>>virus.

>>>I would prefer to give my next talk on a paper that is based on an herbal

>>>formula. This is one of the problems with convincing the scientific

>>>world in the use of herbal medicines. They look for isolated chemicals or

>>>proteins,etc... while a formula containing up to 15 different herbs would

>>>be boggling to the reductionists mind in ascertaining what actually caused

>>>the effect.

>>>There is even talk out there that the Wesern herbalists remedy

>>>for such scepticism, standardized extracts, do not actually have the amount

>>>of standardization they claim to have.

>>>

>>>If anyone has some leads on sites or places I could write away to, to

>>>obtain these papers I would be very interested!

>>>Thanks,

>>>David

>>>

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