Guest guest Posted July 8, 2001 Report Share Posted July 8, 2001 Yes it seems laminal based protein can have a negative effect on bone strength: Full Text HTML: http://biomed.gerontologyjournals.org/cgi/content/full/55/10/M585 Full text PDF: http://biomed.gerontologyjournals.org/cgi/reprint/55/10/M585.pdf The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 55:M585-M592 (2000) Worldwide Incidence of Hip Fracture in Elderly Women Relation to Consumption of Animal and Vegetable Foods Lynda A. Frassettoa, Karen M. Todda, R. Curtis Morris, Jr.a and Anthony Sebastiana a Department of Medicine and General Clinical Research Center, University of California, San Francisco Correspondence: Anthony Sebastian, Box 0126, 1202 Moffitt Hospital, University of California, San Francisco, CA 94143 E-mail: sebastia. William B. Ershler, MD Background. Hip fracture, a major health problem in elderly persons, varies in incidence among the populations of different countries and is directly related to animal protein intake, a finding that suggests that bone integrity is compromised by endogenous acid production consequent to the metabolism of animal proteins. If that is so, vegetable foods might provide a countervailing effect, because they are a rich source of base (bicarbonate) in the form of metabolizable organic anions, which can neutralize protein-derived acid and supply substrate (carbonate) for bone formation. Methods. We analyzed reported hip fracture incidence (HFI) data among countries (N = 33) in women aged 50 years and older, in relation to corresponding country-specific data on per capita consumption of vegetable and animal foods as reported by the United Nations Food and Agriculture Organization. Results. HFI varied directly with total (r = +.67, p < .001) and animal (r = +.82, p < .001) protein intake and inversely with vegetable protein intake (r = -.37, p < .04). The countries in the lowest tertile of HFI (n = 11) had the lowest animal protein consumption, and invariably, vegetable protein (VP) consumption exceeded the country's corresponding intake of animal protein (AP): VP/AP > 1.0. By contrast, among the countries in the highest tertile of HFI, animal protein intake exceeded vegetable protein intake in nearly every case (10 of 11 countries). Among all countries, HFI correlated inversely and exponentially with the ratio of vegetable/animal protein intake (r = -.84, p < ..001) and accounted for 70% of the total variation in HFI. Adjusted for total protein intake, vegetable food consumption was an independent negative predictor of HFI. All findings were similar for the subset of 23 countries whose populations are predominantly Caucasian. Conclusion. The findings suggest that the critical determinant of hip fracture risk in relation to the acid-base effects of diet is the net load of acid in the diet, when the intake of both acid and base precursors is considered. Moderation of animal food consumption and an increased ratio of vegetable/animal food consumption may confer a protective effect. ======================== Interesting that the paper is really about the effect of high acid based foods on bone and published this list of high acid foods. I indented the meat foods to make the list have a second dimension. Potential Acid From Methionine and Cystine (mEq/100 g protein) Grapes 71.1 Walnuts 66.5 Rice 65.4 Chicken 58.4 Wheat bread 58.1 Sweet corn 58.1 Salmon 57.5 Cod 57.5 Ham 56.7 Turkey 56.2 Lamb 54.3 Beef 53.0 Brown rice 50.4 Peaches 46.8 Pineapple 46.3 Oranges 46.2 Buckwheat 46.2 Soybeans 44.9 Potatoes 42.5 Bananas 41.8 Apples 40.4 Chickpeas 39.9 Yam 39.1 Cauliflower 38.3 Black beans 38.3 Zucchini 36.9 Kale 35.2 Tomatoes 32.6 Cabbage 26.9 Broccoli 26.5 =========================== Now you need to address the calcium : protein ratio; Excess Dietary Protein May Not Adversely Affect Bone Full text HTML: http://www.nutrition.org/cgi/content/full/128/6/1054 Full text PDF: http://www.nutrition.org/cgi/reprint/128/6/1054.pdf Which argues that maintaining a calcium : protein ratio of 20 mg calcium : 1 g protein will eliminate any bone loss from dietary calcium. ========================== And then the effect of alkali buffers & potassium Excess Dietary Protein Can Adversely Affect Bone Full text HTML: http://www.nutrition.org/cgi/content/full/128/6/1051 Full text PDF: http://www.nutrition.org/cgi/content/full/128/6/1051 The average American diet, which is high in protein and low in fruits and vegetables, generates a large amount of acid, mainly as sulfates and phosphates. The kidneys respond to this dietary acid challenge with net acid excretion, as well as ammonium and titratable acid excretion. Concurrently, the skeleton supplies buffer by active resorption of bone. Indeed, calciuria is directly related to net acid excretion. Different food proteins differ greatly in their potential acid load, and therefore in their acidogenic effect. A diet high in acid-ash proteins causes excessive calcium loss because of its acidogenic content. The addition of exogenous buffers, as chemical salts or as fruits and vegetables, to a high protein diet results in a less acid urine, a reduction in net acid excretion, reduced ammonium and titratable acid excretion, and decreased calciuria. Bone resorption may be halted, and bone accretion may actually occur. Alkali buffers, whether chemical salts or dietary fruits and vegetables high in potassium, reverse acid-induced obligatory urinary calcium loss. We conclude that excessive dietary protein from foods with high potential renal acid load adversely affects bone, unless buffered by the consumption of alkali-rich foods or supplements. ======================== So it seems the question of animal protein causing bone loss is actually one of eating too many acid based foods (which need not be animal protein!), not enough calcium and not enough potassium / alkali rich foods. Throw in low Vit D / Vit K and you have the reason high acid protein foods MAY effect bone strength in a negative way. Solution, eat the protein source you choose, but get ample amounts of calcium, alkali bases, potassium, Vit D & K. ======================== Good Health & Long Life, Greg Watson, http://www.ozemail.com.au/~gowatson gowatson Quote Link to comment Share on other sites More sharing options...
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