Herb drug interaction

[Guest guest]

I'm wondering if anyone can help me with this....does Lotrel, a high blood

pressure medication have any contraindications for chinese herbs

(categories). My client asked me this question and unfortunately I had no

answer. I tried to log on to the IBIS website, but it wasn't working

properly. Has anyone found their software particularly useful??

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[Guest guest]

, " Julie Smith " <rockymtnacupt@h...>

wrote:

>

>

> I'm wondering if anyone can help me with this....does Lotrel, a

high blood

> pressure medication have any contraindications for chinese herbs

> (categories).

 

Julie:

 

Lotrel is a combination of amlodipine (a calcium channel blocker) and

benazepril (an ACE inhibitor). Both achieve their BP lower effect by

inhibiting the strength of contraction of vascular smooth muscle

(i.e. by causing periperal vasodilation).

 

Herbs catagorized hypotensive/bradycardic, hypertensive/tachycardic,

or vasodilator may inhibit or accentuate the effects of the drug.

Theoretically huang qin, ren shen, sheng jiang, huang lian, bai guo

have vasodilator effects that could accentuate the response and ma

huang has hypertensive/tachycardic properties that could counter the

expected response.

 

This info comes from my lecture notes for Pharmacology. I think the

source was IBIS. I have found IBIS of some limited usefulness for my

needs. It is primarily oriented toward western herbalism but does

reference a few Chinese herbs, but from a western herbal perspective.

 

Hope this helps.

 

Michael Buyze