Guest guest Posted February 18, 2002 Report Share Posted February 18, 2002 western science catches up once again... This is about half of an article from Monday. Specific Brain Area Suspected of Muting, Magnifying Bad Moods By SHANKAR VEDANTAM, WASHINGTON POST A region of the brain a few inches behind the bridge of the nose may hold the key to why some people have a negative outlook on life, scientists announced last week. The study, published in the Proceedings of the National Academy of Sciences, is the first to examine the neurological roots of what scientists call " negative affect, " a trait that predisposes people to anxiety, irritability, anger and a range of other unpleasant moods. By suggesting that an unconscious disposition toward these emotions may be molded by a specific area in the brain, the research moves into previously uncharted waters. It is part of a broad effort by neuroscientists to use powerful brain imaging technology to pinpoint the areas of the brain responsible for various emotions. " It touches on an important issue: the relationship between individual differences in personality and brain function, " said Marcus Raichle, a professor of radiology and neurology at Washington University in St. Louis. " There have been for many, many years attempts to explain the differences we observe among ourselves--[why] we have different personalities. " If you believe behavior and brain are related, you would have to suppose there are differences in brain systems that lead to differences in personality, " he said. For the study, scientists at Vanderbilt University, the Veterans Affairs Medical Center in Minneapolis and the University of Minnesota asked 89 healthy people to take detailed tests that measured their emotional outlook over the previous month. The tests were designed to screen out people's mood states on the day they were evaluated and look instead for a pattern of emotional attitudes--in other words, an outlook or a temperament. While the subjects rested after the tests, the researchers conducted brain scans that measured changes in blood flow within their brains. The scientists found that increased brain activity in one particular region--the ventromedial prefrontal cortex--was associated with those who reported greater negative affect. Many factors besides physiology are responsible for personality, and other parts of the brain are involved in emotions. But researchers say the circumstantial evidence indicates that the ventromedial prefrontal cortex acts as a sort of volume knob for emotions. While the emotions may be produced elsewhere in the brain in response to stimuli, this region of the brain can make them deafening or muted. As a result, some people may react sharply in a situation, while others appear unruffled. The volume knob, in other words, may be what people interpret as temperament. Quote Link to comment Share on other sites More sharing options...
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