Guest guest Posted August 19, 2002 Report Share Posted August 19, 2002 Thomas you wrote: 1st, calcium citrate has been proven to be safe and effective for helping patient with osteoporosis. It is also has been shown to increase bone density in younger and older population. I was wondering what the reference was for this study. My point was that we had a citation for hydroxyapatite; is there one for citrate from a peer reviewed journal, not the metagenics literature? as for absorption, check out this study from a peer reviewed nutrition journal. I have bolded the take home message. I am sure one can find rebuttal studies, but this study proves the jury is still out. Note the recent date of publication in 2001. Metagenics began making it citrate claims in the mid 90's. I believed them, too. But should I? Perhaps the 6 dollar stuff is just as good. If that's true, I definitely want my patients to know. J Am Coll Nutr 2001 Jun;20(3):239-46 Related Articles, Books, LinkOut Absorbability and cost effectiveness in calcium supplementation. Heaney RP, Dowell SD, Bierman J, Hale CA, Bendich A. Creighton University, Osteoporosis Research Center, Omaha, Nebraska 68131, USA. rheaney BACKGROUND: Cost-effectiveness of calcium supplementation depends not only on the cost of the product but on the efficiency of its absorption. Published cost-benefit analyses assume equal bioavailability for all calcium sources. Some published studies have suggested that there are differences in both the bioavailability and cost of the major calcium supplements. DESIGN: Randomized four period, three-way cross-over comparing single doses of off-the-shelf commercial calcium supplements containing either calcium carbonate or calcium citrate compared with a no-load blank and with encapsulated calcium carbonate devoid of other ingredients; subjects rendered fully vitamin D-replete with 10 microg/day 25(OH)D by mouth, starting one week prior to the first test. SUBJECTS: 24 postmenopausal women METHODS: Pharmacokinetic analysis of the increment in serum total and ionized calcium and the decrement in serum iPTH induced by an oral calcium load, based upon multiple blood samples over a 24-hour period; measurement of the rise in urine calcium excretion. Data analyzed by repeated measures ANOVA. Cost calculations based on average retail prices of marketed products used in this study from April through October, 2000. RESULTS: All three calcium sources (marketed calcium carbonate, encapsulated calcium carbonate and marketed calcium citrate) produced identical 24-hour time courses for the increment in total serum calcium. Thus, these were equally absorbed and had equivalent bioavailability. Urine calcium rose slightly more with the citrate than with the carbonate preparations. but the difference was not significant. Serum iPTH showed the expected depression accompanying the rise in serum calcium, and there were no significant differences between products. CONCLUSION: Given the equivalent bioavailability of the two marketed products, the cost benefit analysis favors the less expensive carbonate product. Chinese Herbs " Great spirits have always been violently opposed by mediocre minds " -- Albert Einstein Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 21, 2002 Report Share Posted August 21, 2002 Alon, Guy, all, I'm curious if any of the therapies that are recommended to increase bone mass have actually been proven to do so. I have heard of studies on osteoporosis rate between countries that consume a lot of dairy vs. those that do not and the rates are higher in milk consuming countries. Any thoughts? Colleen Most western nutritionists agree that the first line of treatment in the case is to use a calcium/magnesium combination >>>Most studies show that CA supplementations can not increase bone density Alon Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 21, 2002 Report Share Posted August 21, 2002 If you eat sugar without the minerals required to digest it, the body has to get the necessary minerals from your bones. If you eat sweets in the form of whole fruit and vegetables like sweet potatoes and carrots, the food has the minerals in it, so the calcium and other minerals stay in the bones. If you eat too much protein you will lose calcium. If you are sedentary you will lose bone mass. Toham Kum Rah, Dana Corbin Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 21, 2002 Report Share Posted August 21, 2002 Ipriflavone, D3, Ca, progesterone, and DHEA have weak evidence, with some conflicting studies and mostly done by manufactures Alon Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 21, 2002 Report Share Posted August 21, 2002 In a message dated 8/18/2002 10:09:15 AM Eastern Daylight Time, drgrporter writes: Dear Todd: I was also thinking about the fact that the citrate form stays in the blood longer and therefore that it might be good for treating certain types of fibromyalgia patients. And from my experience and reading, there is often a strong wind component in patients with this western/allopathic diagnosis. SO I think we might have come to the same conclusion from different directions. Most western nutritionists agree that the first line of treatment in the case is to use a calcium/magnesium combination, and perhaps the citrate form may be one of the best if it stays in the extracellular fluid longer. Guy Porter Why would calcium that stays in the blood longer be a good thing? It seems to me that if the calcium was easy to assimilate, it would exit the blood quicker because it was being used by the body. Feedback appreciated. Thanks, Chris Quote Link to comment Share on other sites More sharing options...
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