Calcium supplement

[Guest guest]

Hi

 

*Thomas

 

*you wrote:

1st, calcium citrate has been proven to be safe

and effective for helping patient with osteoporosis.

It is also has been shown to increase bone density in

younger and older population.

 

 

* as for absorption, check out this study from a peer

reviewed nutrition journal. I have bolded the take

home message. I am sure one can find rebuttal

studies, but this study proves the jury is still out.

Note the recent date of publication in 2001.

Metagenics began making it citrate claims in the mid

90's. I believed them, too. But should I? Perhaps

the 6 dollar stuff is just as good. If that's true, I

definitely want my patients to know.

 

*J Am Coll Nutr 2001 Jun;20(3):239-46 Related

Articles, Books, LinkOut

 

*Absorbability and cost effectiveness in calcium

supplementation. Heaney RP, Dowell SD, Bierman J,

Hale CA, Bendich A. Creighton University, Osteoporosis

Research Center, Omaha, Nebraska 68131, USA.

 

 

===> The reference you quote is from a reliable

source. I have long been a fan of Heaney...most of

his research has been on calcium supplement. I have

read this article when it published. However, as you

have indicated, the reference is from 2001...quite new

and have yet stood the test of time...don't get me

wrong... my point is new article is not always the

best reference. Good article must stand the test of

time. By the way, do you know that the calcium

carbonate studied in this paper is taken from OsCal,

manufactured by GlaxoSmithKline?...and do you know

that it is the GlaxoSmithKline that fund this

study?...hmm, what's the exclusion criteria of their

subjects...do you remember how many samples were taken

from each woman for analysis...and how many days were

the experiment conducted.

 

 

*I was wondering what the reference was for this

study. My point was that we had a citation for

hydroxyapatite; is there one for citrate from a peer

reviewed journal, not the metagenics literature?

 

===> N. Engl. J. Med. 323: 878-883. A controlled trial

of the effect of calcium supplementation on bone

density in postmenopausal women. B Dawson-Hughes is

the primary author. I am also a great fan of

Dawson-Hughes, who also has done a lot of work on

calcium supplement. This article is well reference,

and it is a MUST-READ.

 

===> American Journal of Clinical Nutrition, Vol 60,

592-596. Effect of calcium citrate supplementation on

urinary calcium oxalate saturation in female stone

formers: implications for prevention of osteoporosis,

by BS Levine, JS Rodman. This study demonstrated that

calcium citrate supplement is safe for women who

had/have a history of renal calculi. In addition, it

shows that the PTH level was suppressed by 9 ng/L

after 6 months of supplementation.

 

===> Endocrinol Invest 1998 Apr;21(4):263-7.

Comparative study of the intestinal absorption of

three salts of calcium in young and elderly women, by

Praet JP, Peretz A, Mets T, Rozenberg S. This study

demonstrated that 1000 mg/day of soluble calcium

citrate increase plasma calcium concentration in both

young and old population.

 

===> Am J Nephrol 2000 Jan-Feb;20(1):48-52. Acute

effects of oral calcium load on parathyroid function

and on bone resorption in young men, by Guillemant J.

Again, this study demonstrated that 1000 mg/day of

calcium suppress PTH level and reduce the bone

resoprtion rate.

 

Have fun reading.

 

Humbly yours,

Thomas

 

** The true measurement of success is not how many

servants one has, but how many people one serves **

 

 

 

 

 

 

 

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