placenta previa

[Guest guest]

Rory,

How did it go with your pregnant lady? I am also on a midwifery list

and this subject has come up before. They have said that the problem can

correct itself as the pregnancy progresses. I'm posting an interesting

abstract on Huang Qi that might be of interest. Sharon may have some

experience treating this and a bit more information for you.

 

Colleen

 

 

Biol Pharm Bull 2002 Jan;25(1):77-80 Related Articles, Books, LinkOut

 

 

 

Effect of Astragali radix extract on lipopolysaccharide-induced

inflammation in human amnion.

 

Shon YH, Kim JH, Nam KS.

 

Department of Pharmacology, College of Medicine and Intractable Disease

Research Center, Dongguk University, Sukjang-Dong, Kyongju, Korea.

 

The effects of Astragali radix extract on interleukin (IL)-6 and tumor

necrosis factor (TNF)-alpha productions, prostaglandin E2 (PGE2)

biosynthesis, and leukotriene C4 (LTC4) production from

lipopolysaccharide (LPS)-stimulated human amnion cells were

investigated. Amnion cells produced detectable amounts of both IL-6 and

TNF-alpha under LPS-stimulated conditions. Astragalus extract inhibited

the production of IL-6. However, TNF-alpha production was not inhibited

by the extract on L929 cytotoxicity assay. Treatment of amnion cells

with LPS for up to 24 h resulted in an increase in PGE2 release in a

concentration- and time-dependent manner. The extract (150 mg/ml)

significantly inhibited the output of PGE2 by amnion cells (p<0.01). The

arachidonate lipoxygenase metabolite (LTC4) was increased by LPS

treatment of amnion cells. Astragalus extract (30 mg/ml) inhibited LTC4

production by approximately 65% throughout the culture period. These

results suggest that Astragali radix extract may have a role in

inhibiting bacterial infection-associated preterm labor by suppressing

the productions of IL-6, PGE2, and LTC4 by human amnion cells.

 

PMID: 11824562 [PubMed - indexed for MEDLINE]