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peppermint study

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This is interesting, because like the bulk of herbal research worldwide,

it is done on a single herb, not a formula. It shows better results than

the chinese herb formula in symptom relief and it is completely

standardized. However, no long term followup was reported. If we can get

better symptom relief with no iatrogenesis by incorporating such

" specifics " , I do not see the harm. Since bo he is indicated for many IBS

patients as it treats qi constraint and liver overacting on spleen, I

would use the enteric form if it is indicated. However, consider saw

palmetto as another example of using " specifics " . that herb strikes me as

a kidney yin tonic that clears heat from the lower jiao (like zhi mu

perhaps, but not as cold). It may not be appropriate in cases of dampheat.

but I digress...

 

Enteric-coated Peppermint-oil Capsules in the Treatment of Irritable Bowel

Syndrome: A Prospective, Randomized Trial

------

AUTHOR :

Liu JH, Chen GH, Yeh HZ, Huang CK, Poon SK

SOURCE:

J Gastroenterol. 1997, 32(6): 765-768.

OBJECTIVES:

To determine the efficacy and tolerability of an enteric-coated

peppermint-oil formulation (Colpermin.) A prospective, randomized, double

blind, placebo-controlled clinical study in 110 outpatients (66 men/44

women; 18-70 years of age) with symptoms of irritable bowel syndrome was

conducted.

METHOD:

Patients took one capsule (Colpermin or placebo) three to four times daily,

15-30 min before meals, for one month. Fifty-two patients on Colpermin

and 49 on placebo completed the study.

RESULTS:

Forty-one patients on Colpermin (79%) experienced an alleviation of the

severity of abdominal pain (29 were pain-free); 43 (83%) had less

abdominal distension, 43 (83%) had reduced stool frequency, 38 (73%) had

fewer borborygmi, and 41 (79%) less flatulence. Corresponding figures for

the placebo group were: 21 patients (43%) with reduced pain (4 were

pain-free), 14 (29%) with reduced distension, 16 (32%) with reduced stool

frequency, 15 (31%) with fewer borborygmi, and 11 (22%) with less

flatulence. Symptom improvements after Colpermin were significantly better

than after placebo (P < 0.05; Mann-Whitney U-test). One patient on

Colpermin experienced heartburn (because of chewing the capsules) and one

developed a mild transient skin rash.

Chinese Herbs

" Great spirits have always found violent opposition from mediocre

minds " -- Albert Einstein

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Enteric-coated Peppermint-oil Capsules in the Treatment of Irritable Bowel Syndrome: A Prospective, Randomized Trial>>>Todd

The few cases in which i tried enteric peppermint (phytopharmica) did not do very well, while they did do quite well with TCM. Obviously this is no evidence but i thought I might share

Alon

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I usually use TCM for IBs with good results, however I have seen IBS sx

completely disappear many times with phytopharmaica peppermint. but they

come back soon after discontinuation. it is no cure.

 

 

, " Alon Marcus " <

alonmarcus@w...> wrote:

> Enteric-coated Peppermint-oil Capsules in the Treatment of Irritable Bowel

Syndrome: A Prospective, Randomized Trial

> >>>Todd

> The few cases in which i tried enteric peppermint (phytopharmica) did not

do very well, while they did do quite well with TCM. Obviously this is no

evidence but i thought I might share

> Alon

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