Guest guest Posted May 16, 2003 Report Share Posted May 16, 2003 I checked with Curt Jacquot at Pacific Biologic regarding studies done with his formula for lowering cholesterol. He currently only has individual case studies. No large studies. Having said that, he's will to provide product plus placebos to practitioners who want to try to run clinical trials. His formula was put together by Dr. Ping Qi Kang, former chief of TCM at Shanghai Hosptial #1. It was designed to rely on herbs commonly imported into the U.S. from China. Nothing fancy or esoteric about the herbs. Any takers? Give Curt a call at 925-673-2967. He might not support a study of thousands, but if PCOM clinic or another clinic can enlist the patients, Curt is willing to send you product. It might be worth a paper in a journal for who ever organizes it. All the Best, Emmanuel Segmen Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 17, 2003 Report Share Posted May 17, 2003  His formula was put together by Dr. Ping Qi Kang, >>>What's in it alon Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 18, 2003 Report Share Posted May 18, 2003 His formula was put together by Dr. Ping Qi Kang, >>>What's in it alon ArteClear® Ingredients: Latin Name Chinese Name English Name Rheum Palmatum Rhizoma Da Huang Rhubarb Rhizome Salvia Miltiorrhiza Radix Dan Shen Salvia Root Sargassum Pallidum Herba Hai Cao (Zao) Sea Weed Polygonum Multiflorum Radix He Shou Wu Polygonum Root Polygonatum Sibiricum Rhizoma Huang Jing Polygonatum Rhizome Cassia Tora Semen Jue Ming Zi Cassia Seeds Aucklandia Lappe Radix Mu Xiang Aucklandia Root Crataegus Pinnatifida Fructus Shan Zha Hawthorn Fruit Panax Notoginseng Radix Tian Qi Pseudoginseng Root Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 18, 2003 Report Share Posted May 18, 2003  Emmanuel thanks Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 20, 2003 Report Share Posted May 20, 2003  Here is an email from the Pharmnex study researchers on red yeast rise Alon There were 1.5 mg of Monacolin K or lovastatin in the 300 mg red yeast andrice capsule and subjects took four per day. They resulted in a lowering ofcholesterol of 20% which would correspond to 20 mg mevacor so we think theother monacolins or other substances were active. DH Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 20, 2003 Report Share Posted May 20, 2003 Alon, Susan Braverman, one of David Heber’s collaborators at UCLA, read to me from their published report that the cholestin study material contained 2.46mg of Monacolin K per capsule and that there were 600mg of RYR per capsule. This works out to 0.41%. They took 4 capsules, or 2400mg per day. This works out to 9.84mg of Monacolin K per day, which is, as you have suggested, a pharmaceutically equivalent dose. Perhaps this is why the FDA has banned this supercharged material from the dietary supplement marketplace. Several years ago I had a number of RYR products, including cholestin, tested by an NIH-funded lab for their HMG CoA reductase inhibition activity in a bioassay. The researcher’s results indicated that the enzyme inhibition activity of the RYR, compared to pharmaceutical statins, was 1/100th the strength. Somehow the spectrum of information that I now have does not add up. Nonetheless, I have just received a shipment of RYR that will be used in a next study about to begin at UCLA that will look at RYR metabolism relevant to safety issues. The specifications of the material were that it be the same strain and potency that was used in the previous study. When I receive the C of A I will know what that is stated to mean. Stephen Here is an email from the Pharmnex study researchers on red yeast rise Alon There were 1.5 mg of Monacolin K or lovastatin in the 300 mg red yeast and rice capsule and subjects took four per day. They resulted in a lowering of cholesterol of 20% which would correspond to 20 mg mevacor so we think the other monacolins or other substances were active. DH Chinese Herbal Medicine, a voluntary organization of licensed healthcare practitioners, matriculated students and postgraduate academics specializing in Chinese Herbal Medicine, provides a variety of professional services, including board approved online continuing education. Your use of is subject to the Terms of Service. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 20, 2003 Report Share Posted May 20, 2003 Susan Braverman, one of David Heber’s collaborators at UCLA, read to me from their published report that the cholestin study material contained 2.46mg of Monacolin K per capsule and that there were 600mg of RYR per capsule. This works out to 0.41%. They took 4 capsules, or 2400mg per day. This >>>>Stephen The statement below was emailed to me from one of the authors of a study i believe was at UCLA. It looked like the Pharmanex study (There were 1.5 mg of Monacolin K or lovastatin in the 300 mg red yeast andrice capsule and subjects took four per day. They resulted in a lowering ofcholesterol of 20% which would correspond to 20 mg mevacor so we think the other monacolins or other substances were active.) Also Like I said the one i use is supposed to be 0.5% which would make it even much stronger. I wander if it is not spiked with phram mevacor. I also seen a product with high monacolin B which i think is lipitor Alon Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 20, 2003 Report Share Posted May 20, 2003 I wander if it is not spiked with phram mevacor. I also seen a product with high monacolin B which i think is lipitor Alon Alon, It is certainly possible that the material you are buying is spiked with synthetically produced statin components. There are ways to differentiate between the naturally occurring and synthetic but it has been too many years now to recall details other than that the naturally occurring statins manifest in a more complex and balanced combination of monacolins than the synthetically spiked material. So if you looked at an HPLC graph or had credible data that indicated a relatively balanced spectrum of monacolins then it might help allay your concerns. Personally, I would choose a different approach to prevention of heart disease than a quasi-pharmaceutical high-statin containing material. The safety of long term, high statin RYR use at a high dose is certainly reasonable to question. In fact if you don’t, you could be legally at risk since the FDA has “spoken” on this issue. Stephen Chinese Herbal Medicine, a voluntary organization of licensed healthcare practitioners, matriculated students and postgraduate academics specializing in Chinese Herbal Medicine, provides a variety of professional services, including board approved online continuing education. Your use of is subject to the Terms of Service. Quote Link to comment Share on other sites More sharing options...
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