Guest guest Posted October 28, 2003 Report Share Posted October 28, 2003 Hi All, I see little problem in measuring outcomes of therapy, be it conventional medicine, AP or CHM. The usual convention is to establich a BASELINE for physiological and other parameters of interest, and the severity of S & Ss pre- treatment, using measurable units. For example parameters to be measured might include: 1. Bodyweight [in lbs or kg] 2. Blood pressure [mm Hg systolic & diastolic] 3. Heart Rate [beats/min] 4. Respiration rate [breaths/minute], coughs/hour, expectoration volume (ml/day] and inspiration and expiration power [as used in asthma assessment] 5. Body temp [DegC or DegF] 6. serum enzymes, glucose, BUN, bilirubin, etc] 7. Urine output [ml/urination and total ml/day], urination speed [ml/minute from start to end of each urination], urination frequency [trips to urinate/day], urine specific gravity (g/ml), urine protein, urine sugar, urine ketone, etc. 8. Faecal output [g/defecation and total g/day], defecation speed [gl/minute from start to end of each defecation], defecation frequency [trips to defecate/day], faecal water content (%), faecal occult blood, faecal bacterial types [E.colii, salmonella, etc], faecal parasite eggs/larvae, etc, faecal protozoal types, etc 9. Drug usage [doses of specific drugs used/day] 10. Hours or days/week in bed. 11. Days/week off work due to the disorder. 12. Number of times [after first sleep] wakened/night, number of trips to toilet after going to bed at night. etc 13. Hand grip, arm strength (adduction/abduction, upward lifting and downward pressing), using an adapted scales or dynanometer. 14. Male sexual activity [number of attempted erections/week, % attempted erections successful, % successful erections that ended in orgasm, orgasms/week, etc] 15. Pace length [mean distance (cm/pace) over 20 paces] etc [lame subjects usually have short pace-length] 17. Joint movement [maximum range of movement [ROM], say of the knee, as measured on a goniometer] 18. [Re shoulder/arm restriction] With the arm raised above the head, how far DOWN the thoracic spines can one reach with each arm [cm from the lower edge of, say, C7]. With the arm placed behind the lumbar area, how far UP the thoracic spines can one reach with each arm [cm from the lower edge of, say, C7] These are all straightforward measurements. Many can be measured by the subject if he/she will comply with keeping the records accurately. In that regard, it is essential to provide each subject with a diary, preformatted to include columns or rows for all parameters to be measured. It is also essential to provide the hardware, or test kits, to be used [for example, scales, dynanometers, stop-watch, measuring cylinders, urine hydrometer, urine-dipsticks, etc]. It is more difficult to score some S & Ss, but most can be scored on visual-analogue-scales (VASs).These can range from 0-5, 0-10, or 0-100, where 0=none and the top score (5, 10 or 100, depending on the scale used) represents the most severe, or almost intolerable, S/S. For example: PAIN (say, VAS 0-10) Spasm (say, VAS 0-10) Dreams, nightmares (VAS 0=none recalled; VAS 10 = severely dream-disturbed sleep) IMO, most if not all subjective and objective indices of health, well- being and dysfunction can be measured directly, or scored on a VAS scale. Comparison of the scores before, at intervals during, and at 3, 6 and 12 months after the start of therapy can give a reasonable assessment of the subject's clinical outcome to Tx. IMO, it is possible to compare many forms of therapy if sufficient subjects are studied in properly randomised groups. For example, one could compare the Pre-Post Tx outcomes for : (1) Negative Control [No Tx, or a placebo Tx [say lactose tablet]]; (2) AP Tx; (3) CHM Tx; (4) Positive Control [ " state of the art " conventional Tx] Individualised Tx, as in expert AP or CHM, poses special difficulties in randomised double-blind controlled studies. However, IMO, it is a cop-out [and adverse for the public- and scientific- image of alternative/complementary therapies] for us to claim that they cannot be researched side-by-side with conventional (allopathic) therapies in an unbiased and objective way. Where there is a will [and adequate research funding!], there is a way ... Best regards, Email: < WORK : Teagasc Research Management, Sandymount Ave., Dublin 4, Ireland Mobile: 353-; [in the Republic: 0] HOME : 1 Esker Lawns, Lucan, Dublin, Ireland Tel : 353-; [in the Republic: 0] WWW : http://homepage.eircom.net/~progers/searchap.htm Quote Link to comment Share on other sites More sharing options...
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