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Heiner Fruehauf has written and lectured at length for the past few

years about his take on Gu syndrome.  Gu syndrome is the result of some

sort of evil infestation.  This may include worms, protozoa, bacteria

and viruses from the modern perspective.  In ancient times. gu syndrome

was associated with demonic possession, because of the bizarre mental

symptoms patients often exhibit.  Because of this textual emphasis on

demons, the modern communists were pretty quick to jettison this

pattern when they standardized TCM.  However, the frequent mention of

GU in classical texts and the claims of cure for stubborn chronic

ailments caught the eye of Fruehauf.

 

Fruehauf practices in Portland, Oregon and has seen a lot of knotty

cases over the years.  We mentioned Dr. Fruehauf earlier in the lesson

on the six stage theory.  Fruehauf was trained inthe classical method

of zhang zhong jing and relies heavily on these ancient formulae in his

practice.  Fruehauf also likes Li dong yuan’s dynamic method of

regulating the stomach and spleen, so he has always focused on the qi

mechanism in his teaching and practice.  However, certain patients with

chronic digestive and mental complaints were not getting well using

standard methods.  Noting that many of these patients had presently or

previously tested positive for various parasites led Dr. Fruehauf on a

peculiar journey through the archive of Chinese medicine.  In the

process, he unearthed another piece of the puzzle of how to treat

chronic illness through regulation of the qi mechanism.

 

It is important to begin with the understanding that gu syndrome is not

an acute parasite invasion.  It often begins that way, but according to

Fruehauf, gu is the “state of extreme stagnation and mental and

physical decay ... [caused] by parasites that combine their toxic

potential to gradually putrefy the patient’s body and mind.”34  Other

characteristics of Gu reinforce its association with mysterious chronic

illnesses.  Gu causes noticeable problems long after an initial

infection was apparently resolved.  Patients often experience diverse

unusual groups of symptoms.  Digestive symptoms can be severe and

painful, with aberration of appetites and cravings.  Symptoms of hot,

cold, photophobia and fibromyalgia/arthralgia are common.  Depression,

anger, anxiety, insomnia are a few of many mental aberrations. 

Patients may feel possesed or even have seizures.  So food allergy,

candida, multiple chemical sensitivity, fibromyalgia and other common

diagnoses may all be related to gu syndrome in some cases.

 

According to Fruehauf, Gu only occurs in a weakened individual, so the

therapeutic approach relies on strategies that supplement deficiency as

well as expel gu toxins.  Longterm gu patients cannot handle the very

hot or very cold herbs often used to treat parasites.  They are thus

prescribed rather unusual formulae that kill parasites directly in some

cases, but focus more on calming the mind, as well as supplementing and

moving both the qi and the blood.  The herbs selected in these various

categories are specific for their anti-gu nature.  Not just any herbs

will do.  The key to anti-gu therapy is the use of large dosages of

surface relieving herbs.  According to Fruehauf, large dosages of

surface relieving herbs like bo he and zi su ye have a penetrating

effect on the system.  They illuminate the dark places where gu toxins

lodge and allow the other herbs in the formula to reach to every

crevice of the body.35

 

Bob Flaws has noticed that the formulae suggested for gu syndrome bear

a striking resemblance to Li dong yuan’s methodology for yin fire

discussed above.36  Remember, Li was famous for his explicit use of

surface relieving herbs to ascend the spleen qi.  While zhang zhong

jing was the first to actually do this, Li was the first to write about

this methodology at length.  So both approaches use surface relieving

herbs, tonics and heat clearing agents simultaneously to treat a

problem rooted in the digestive system.  However, there are distinct

differences, as well.  According to Fruehauf, Gu specialists used much

larger doses of surface relievers than spleen/stomach specialists

because their intent was penetration of the darkest recesses where gu

may have lodged, rather than merely uplifting the qi.  Fruehauf has

also stated that certain tonics are also prohibited in Gu, particularly

ginseng, one of Li’s favorites.  Ginseng is said to worsen gu and is

often used as a diagnostic indicator thereof (i.e. if a very depleted

patient becomes violently ill upon taking ginseng, you should consider

gu syndrome).37

 

In any event, there are distinct relationships between certain aspects

of gu treatment and regulation of the qi mechanism.  First, the very

nature of gu is to disrupt the qi mechanism.  The traditional

description of gu is that of oil mixing with flour.39  Basically, the

toxin has seeped into and bound up with the tissues of the body.  This

can only happen when the body becomes incapable of separating pure and

turbid.  In the weakened patient, food-borne parasites that are not

fully expelled remain in the central and lower burners brewing and

putrefying.  Thus, the pure is now unable to ascend , the most profound

sign of this being the mental aberrations.  The turbid fails to be

descended and excreted properly.  The accumulation of turbidity and

toxicity further aggravate the GI and mental symptoms.  Meanwhile, the

body is unable to replenish it’s postnatal jing from food and the

kidneys are thus drained of their essences.

 

We often see our old friend dampheat associated with gu, especially if

no strong cooling treatments have yet been applied.  It is common to

treat chronic parasites with strong cooling antimicrobials like

berberine, flagyl, nystatin, capryllic acid, etc.40  While these

substances may have some role in gu therapy, according to Fruehauf,

they do not address the deep penetration of the toxin outside the GI

tract nor do they restore the qi mechanism in any way.  Treating

dampheat makes sense at this stage, but standard dampheat treatments

will not work on gu patients.   So while herbs like lonicera,

forsythia, sophora and artemisia qing hao are used to clear dampheat 

toxin, they must be combined with the penetrating herbs like zi su ye. 

So like most of our other approaches, dampheat and the qi mechanism are

at the core of this pathology and the therapeutic approach described in

ancient texts implicitly recognizes this in formula design.

 

Fruehauf discusses two basic gu patterns.  The first is more of the

dampheat pattern we have been discussing so far.  The recommended

formula is called su he tang and was originally recorded in Zhi Gu Xin

Fang (New Methods for Gu Treatment, Lu Shunde, Qing Dynasty).  Since

this formula also includes cooling moistening herbs and mild yin tonics

like sheng di, xuan shen, huang jing and bai he, it is as much of an

homage to zhu dan xi as li dong yuan, perhaps.  Remember, it was zhu

who focused on the enduring damage to yin fluids that was caused by

dampheat, which itself arose due to qi mechanism disruption.  There

seems to be something counterintuitive about choosing such herbs in a

bloated digestive condition, yet Fruehauf puts great emphasis on herbs

like sheng di, xuan shen, huang jing and bai he in this condition, as

well as qi lifting tonics like huang qi.

 

Bob Flaws has pointed out that zhu dan xi actually wrote about gu in

his seminal Ge Zhi Yu Lun.41  The chapter in question is titled " Drum

Distension " (chinese: gu zhang).  While the gu that means drum is a

different character than the gu that means " worm " , the worm-gu is often

substituted for the drum-gu in the term gu zhang.  This is because drum

distension is often related to gu poison.  Drum distension is a severe

form of abdominal pain.  According to Wiseman in his Practical

Dictionary of TCM, drum distension is almost always related to liver

spleen disharmony.  It is often caused by alcoholism, as well as gu

poison.  According to both Flaws and Fruehauf,42 Zhu appears to state

that drum distension is essentially synonymous with gu-worm distension.

 

However, Zhu's indicated formulae focus on supplementing deficiency,

rather than attacking gu poison directly.  While there is definitely

similarity between Zhu's herb selection and that of Fruehauf, the

absence of penetrating wind medicinals and anti gu toxin clearing herbs

is notable.  Like Fruehauf, Zhu makes the point that gu is a severe

deficiency condition and treats accordingly.  Yet the absence of herbs

that directly attack worms leads me to believe that Zhu was using the

term gu-worm in a more general sense of poison penetrating the system,

yet not involving parasites.  Zhu also uses Ginseng, which Fruehauf has

declared a prohibited herb in gu syndrome, a point Flaws disputes.43 

Nevertheless, Zhu's explanation of the gu pathomechanism and formula

selection is instructive for us.  He puts considerable emphasis on the

qi mechanism and dampheat, as we would now expect. In his own words,

 

" The seven affects damage the internal, the six environmental excesses

invade from outside, food and drink are had without restraint, and

chamber taxation causes vacuity. [Any of these causes may] damage

spleen earth yin [and consequently,] the office of transportation and

conveyance may fail to carry out its duty. Although the stomach [still]

receives grains, [the spleen] cannot transport or transform them. As a

result, yang keeps on upbearing itself and yin keeps on downbearing

itself, resulting in the disadvantageous divorce between heaven and

earth. When this happens, clearness and turbidity are confused together

and the tunnels are congested and held up. Qi transforms into the

turbid, and blood becomes stagnated with depressive heat [being

generated]. When heat remains for long, qi transforms into dampness.

Dampness and heat mutually engender, thus giving rise to distention and

fullness. This is what the classic calls drum distention because,

though hard and full, the abdomen is empty with nothing inside, [thus]

resembling a drum. The disease is persistent, firmly fixed, and

difficult to cure. It is also called gu. Because it is as if [one were]

invaded and being eaten by worms, therefore, [this kind of distention]

is called gu. " 44

 

 

Fruehauf also presents a cold gu syndrome and his chosen formula, jia

jian su he tang, is very similar to variations of li dong yuan’s famous

bu zhong yi qi tang (minus the ginseng, of course).  Unlike zhu’s

variation, Fruehauf’s does not use cooling herbs, but actually warming

and qi moving herbs at this stage, so he is obviously describing a more

classic cold condition in this case, rather than a yin fire

syndrome.45  In clinic, one may actually prescribe something more

between the hot and cold type gu formula.  The net result would

probably look a lot like the formulae recommended by both Zhu dan xi

and li dong yuan for this type of condition (i.e. chronic illness

rooted in vacuity with concomitant heat and stasis).   What this

reinforces is that there are multiple causes of qi mechanism disharmony

and treatment varies accordingly.  In some cases, similar strategies

may be used for diverse etiology, so it is always vital to evaluate the

case carefully.  Gu syndrome is a difficult diagnosis to make

properly.  In ancient times, it was largely a diagnosis of exclusion,

determined by failure of other therapies.  In modern times, the

presence of parasites in a stool culture are highly indicative of gu,

however the absence of these pathogens does not rule out gu.  In some

cases, the pathogen is gone and only the poison remains.

 

It is not surprising that gu syndrome is treated with methods that seem

to borrow from the methods of Li Dong Yuan and Zhu Dan xi.  After all,

the gu specialists culminated their theories in the late qing dynasty. 

They were no doubt familiar with the works of these great masters, who

lived many centuries before and were both well known in qing times.  In

addition to treating enduring yin damage with cooling herbs, gu

formulae also address dampheat without overuse of harsh bitter cooling

herbs.  So, as well as using herbs like lian qiao and jin yin hua

instead of ones like huang lian and huang bai, the inclusion of chai hu

and sheng ma as additional standard ingredients surely also represent

the influence of Li Dong Yuan.  The formulae are notable for their

inclusion of qi movers, but the absence of herbs that either purge the

bowels or disinhibit urination.  Thus, a sophisticated variation on the

treatment of yin fire emerges, as Flaws has suggested.

 

 

34.  Fruehauf, Heiner, “Gu Syndrome:  A Forgotten Clinical Approach to

Chronic Parasitism”, Journal of #57, pg. 11

35.  Ibid, pp. 13-14

36.  Flaws, Bob, Gu Parasites & Yin Fire Theory

37.  Fruehauf, Heiner, “Gu Syndrome:  A Forgotten Clinical Approach to

Chronic Parasitism”, Journal of #57, pg. 13

38.  Bob Flaws, Personal Correspondence, 9/24/99

39.  Fruehauf, Heiner, “Gu Syndrome:  A Forgotten Clinical Approach to

Chronic Parasitism”, Journal of #57, pg. 13

40.  Ibid, pg. 15

41.  Flaws, Bob, Zhu dan-xi on Gu Conditions

42.  Fruehauf, personal correspondence, 10/21/99

43.  Bob Flaws, Personal Correspondence, 9/24/99

44.  Flaws, Bob, Zhu dan-xi on Gu Conditions

45.  Fruehauf, Heiner, “Gu Syndrome:  A Forgotten Clinical Approach to

Chronic Parasitism”, Journal of #57, pg. 16

 

 

 

 

Chinese Herbs

 

 

FAX:

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>

>

> Saturday, September 25, 2004 8:49 AM

> cha

> gu essay reformated

>

>

>

> Heiner Fruehauf has written and lectured at length for the past few

> years about his take on Gu syndrome.  Gu syndrome is the result of some

> sort of evil infestation.  This may include worms, protozoa, bacteria

> and viruses from the modern perspective.  In ancient times. gu syndrome

> was associated with demonic possession, because of the bizarre mental

> symptoms patients often exhibit.  Because of this textual emphasis on

> demons, the modern communists were pretty quick to jettison this

> pattern when they standardized TCM.

[Jason]

Didn't this happen way before TCM?

 

-Jason

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Modern CM did not/has not jettisoned the concept of gu worms. You'll

find a definition of gu worms in most, if not all, Chinese language CM

dictionaries, including Wiseman and Feng Ye's English language

dictionary which is based on standard Chinese language sources. There

are two main divisions of worms: 1) visible and 2) invisible. In

modern CM, gu worms are defined as invisible worms. In standard

professional CM, gu worms are associated with the core disease

mechanisms of spleen vacuity, damp heat, and liver depression qi

stagnation.

 

By at least Zhu Dan-xi, gu worms had been reframed into a totally

naturalistic concept by mainstream literate Chinese doctors. According

to Zhu, gu worms are associated with " great spleen vacuity, " damp

accumulation, and qi stagnation. In contemporary CM, Zhu's dampness

has become damp heat.

 

Bob

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>

> Bob Flaws [pemachophel2001]

> Thursday, September 30, 2004 8:58 AM

>

> Re: gu essay reformated

>

> Modern CM did not/has not jettisoned the concept of gu worms.

[Jason]

If this is response to my post, I was referring to the idea of gu worms

being associated with demonic possession.

 

-

 

 

You'll

> find a definition of gu worms in most, if not all, Chinese language CM

> dictionaries, including Wiseman and Feng Ye's English language

> dictionary which is based on standard Chinese language sources. There

> are two main divisions of worms: 1) visible and 2) invisible. In

> modern CM, gu worms are defined as invisible worms. In standard

> professional CM, gu worms are associated with the core disease

> mechanisms of spleen vacuity, damp heat, and liver depression qi

> stagnation.

>

> By at least Zhu Dan-xi, gu worms had been reframed into a totally

> naturalistic concept by mainstream literate Chinese doctors. According

> to Zhu, gu worms are associated with " great spleen vacuity, " damp

> accumulation, and qi stagnation. In contemporary CM, Zhu's dampness

> has become damp heat.

>

> Bob

>

>

>

>

> Chinese Herbal Medicine offers various professional services, including

> board approved continuing education classes, an annual conference and a

> free discussion forum in Chinese Herbal Medicine.

>

>

>

>

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  • 2 weeks later...

Will MacLean's patent (his words Bob!) herb book, he has a chart in

the glossary on the heat - Qi stagnation - Spleen Xu triad called

the Primary Pathological Pyramid, with formulas for the various

areas of the triangle. Interesting read!

Geoff

 

, " Bob Flaws "

<pemachophel2001> wrote:

> are two main divisions of worms: 1) visible and 2) invisible. In

> modern CM, gu worms are defined as invisible worms. In standard

> professional CM, gu worms are associated with the core disease

> mechanisms of spleen vacuity, damp heat, and liver depression qi

> stagnation.

>

> By at least Zhu Dan-xi, gu worms had been reframed into a totally

> naturalistic concept by mainstream literate Chinese doctors.

According

> to Zhu, gu worms are associated with " great spleen vacuity, " damp

> accumulation, and qi stagnation. In contemporary CM, Zhu's dampness

> has become damp heat.

>

> Bob

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