Guest guest Posted November 18, 2004 Report Share Posted November 18, 2004 Hi All, See these. Phil >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> Zhou W, Fu LW, Tjen-A-Looi SC, Li P, Longhurst JC. Afferent Mechanisms Underlying Stimulation Modality-Related Modulation of AP-Related Cardiovascular Responses. J Appl Physiol. 2004 Nov 5; [Epub ahead of print] Coll of Med, Univ of California, Irvine, Irvine, CA, USA. Despite the use of AP to treat a number of heart diseases, little is known about the mechanisms that underlie its actions. Therefore, we examined the influence of AP on sympathoexcitatory cardiovascular responses to gastric distension in anesthetized Sprague-Dawley rats. Thirty min of low frequency, low current (1-2 mA, 2 Hz) electroAP (EA), at PC05-PC06, ST36- ST37 and HT06-HT07 overlying the median, deep peroneal nerve and ulnar nerves significantly decreased reflex pressor responses by 40, 39 and 44%, respectively. In contrast, sham AP involving needle insertion without stimulation at PC05-PC06 or 30 min of EA at LI06-LI07 acupoints overlying the superficial radial nerve did not attenuate the reflex. Similarly, EA at PC05-PC06 using 40 or 100 Hz stimulation frequencies did not inhibit the reflex. Compared to EA at PC05-PC06, EA at two sets of acupoints including PC05- PC06 and ST36-ST37did not lead to larger inhibition of the reflex. Two min of manual AP (MA, 2 Hz) at PC05-PC06 every 10 min for 30 min inhibited the reflex cardiovascular pressor response by 33%, a value not significantly different than 2 Hz EA at PC05- PC06. Single unit afferent activity was not different between electrical and manual stimulation. However, 2 Hz electrical stimulation (ES) activated more somatic afferents than 10 or 20 Hz ES. These data suggest that, although the location of acupoint stimulation and the frequency of stimulation determine the extent of influence of EA, there is little difference between low frequency electro- and manual AP at PC05-PC06. Furthermore simultaneous stimulation using two acupoints that independently exert strong effects did not lead to an additive or a facilitative interaction. The similarity of the responses to EA and MA and the lack of cardiovascular response to high frequency EA appear to be largely a function of somatic afferent responses. PMID: 15531558 [PubMed - as supplied by publisher] Vickers AJ, Rees RW, Zollman CE, McCarney R, Smith CM, Ellis N, Fisher P, Van Haselen R, Wonderling D, Grieve R. AP of chronic headache disorders in primary care: randomised controlled trial and economic analysis. Health Technol Assess. 2004 Nov;8(48):1-50. Integrative Medicine Service, Biostatistics Service, Memorial Sloan-Kettering Cancer Center, New York, USA. OBJECTIVES: To determine the effects of a policy of using AP, compared with a policy of avoiding AP, on headache in primary care patients with chronic headache disorders. The effects of AP on medication use, quality of life, resource use and days off sick in this population and the cost-effectiveness of AP were also examined. DESIGN: Randomised, controlled trial. SETTING: General practices in England and Wales. PARTICIPANTS: The study included 401 patients with chronic headache disorder, predominantly migraine. INTERVENTIONS: Patients were randomly allocated to receive up to 12 AP treatments over 3 months or to a control intervention offering usual care. MAIN OUTCOME MEASURES: Outcome measures included headache score; assessment of Short Form 36 (SF-36) health status and use of medication at baseline, 3 months and 12 months; assessment of use of resources every 3 months; and assessment of incremental cost per quality-adjusted life-year (QALY) gained. RESULTS: Headache score at 12 months, the primary end-point, was lower in the AP group than in controls. The adjusted difference between means was 4.6. This result was robust to sensitivity analysis incorporating imputation for missing data. Patients in the AP group experienced the equivalent of 22 fewer days of headache per year. SF-36 data favoured AP, although differences reached significance only for physical role functioning, energy and change in health. Compared with controls, patients randomised to AP used 15% less medication, made 25% fewer visits to GPs and took 15% fewer days off sick. Total costs during the 1-year period of the study were on average higher for the AP group than for controls because of the AP practitioners' costs. The mean health gain from AP during the year of the trial was 0.021 QALYs, leading to a base-case estimate of GBP9180 per QALY gained. This result was robust to sensitivity analysis. Cost per QALY dropped substantially when the analysis incorporated likely QALY differences for the years after the trial. CONCLUSIONS: The study suggests that AP leads to persisting, clinically relevant benefits for primary care patients with chronic headache, particularly migraine. It is relatively cost-effective compared with a number of other interventions provided by the NHS. Further studies could examine the duration of AP effects beyond 1 year and the relative benefit to patients with migraine with compared to tension-type headache. Trials are also warranted examining the effectiveness and cost-effectiveness of AP in patients with headache receiving more aggressive pharmacological management. PMID: 15527670 [PubMed - in process] Linde K. [should AP be reimbursed? Three AP programmes of German Statutory Health Insurance Funds (SHI) and their scientific evaluation - Article in German] Z Arztl Fortbild Qualitatssich. 2004 Sep;98(6):467-8. Zentrum fur naturheilkundliche Forschung, II. Medizinische Klinik und Poliklinik, Technische Universitat Munchen. Klaus.Linde An estimated 40,000 physicians offer AP treatment to patients in Germany. Due to a decision of the German Federal Committee of SHI-accredited Physicians and Health Insurance Funds, AP treatment for chronic low back pain, headache and osteoarthritic pain may be reimbursed from 2000 onwards if patients and physicians participate in specific scientifically evaluated model projects of the Statutory Health Insurance Funds. Currently, three separate AP programmes are offered by different Statutory Health Insurance Funds. The scientific evaluation of all these programmes includes both randomised trials (comparing AP to no treatment, sham AP or standard treatment in 300 to several thousands of patients) and large cohort studies. Details of the three programmes will be presented in the following chapters. PMID: 15527186 [PubMed - in process] Hayashi M, Sakakura E, Horikawa N, Katakura Y, Kishi R. [Health status and socioeconomic factors related to home remedy practices among elderly subjects living in a community in Okinawa - Article in Japanese]. Nippon Koshu Eisei Zasshi. 2004 Sep;51(9):774-89. Dept of Public Health, Graduate School of Medicine, Hokkaido Univ. OBJECTIVE: The purpose of the present study was to clarify health status and socioeconomic characteristics of elderly persons who practice home remedies as complementary alternative medicine. Whether such usage is associated with health-related factors was also assessed. METHODS: The subjects are 243 independent elderly living at home in A-village of Okinawa prefecture, aged 65 years or older. A self-administered questionnaire was mailed to all subjects in 2001. Included were questions on socioeconomic indicators, health status, IADL, health habits, social network, social support and home remedy practices. All data were statistically analyzed by Student's t test and the chi-square test. In addition logistic regression was used to calculate the odds ratios for current practitioners for each of the factors. RESULTS: The present study included 200 subjects who responded and completed all questions. (Table 2). The main results are as follows: The practitioner rate for home remedies was 50.8% in males and 71.9% in females, the difference being significant (P<0.05). Usage was found to be significantly related to hypertension (P<0.05), arthritis and rheumatic disease (P<0.01), some health habits and provision nursing of social support (OR = P<0.05). Logistic regression analysis adjusted for age, gender, and income revealed current practitioners of AP to have a significantly higher level of history of hospital admission in the previous year (OR = 0.2 P<0.05), food control habits (OR = 4.3 P<0.05) and provision nursing of social support (OR = 4.2 P<0.05) than non-current practitioners. CONCLUSION: The findings suggest that home remedy practices are associated with health-related habit and provision of social support for good quality of elderly life. The purpose is not only physical care but also health maintenance and promotion. PMID: 15526761 [PubMed - in process] >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> Best regards, Email: < WORK : Teagasc, c/o 1 Esker Lawns, Lucan, Dublin, Ireland Mobile: 353-; [in the Republic: 0] HOME : 1 Esker Lawns, Lucan, Dublin, Ireland Tel : 353-; [in the Republic: 0] WWW : http://homepage.eircom.net/~progers/searchap.htm Chinese Proverb: " Man who says it can't be done, should not interrupt man doing it " Quote Link to comment Share on other sites More sharing options...
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