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AP as a complementary therapy in kneef osteoarthritis

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Hi all,

 

See this [thanks to Nicholas Larkins for the alert]:

 

Jorge Vas, chief medical officer1, Camila Méndez, epidemiologist2,

Emilio Perea-Milla, chief medical officer3, Evelia Vega, chief

medical officer7, María Dolores Panadero, pharmacologist2, José

María León, professor4, Miguel Ángel Borge, chief medical officer6,

Olga Gaspar, nurse1, Francisco Sánchez-Rodríguez, technician5,

Inmaculada Aguilar, nurse1, Rosario Jurado, nurse1. AP as a

complementary therapy to the pharmacological treatment of

osteoarthritis of the knee: randomised controlled trial BMJ

2004;329:1216 (20 November), doi:10.1136/bmj.38238.601447.3A

(published 19 October 2004). 1 Pain Treatment Unit, Centro de

Salud " Dos Hermanas A " (Distrito Sanitario Sevilla-Sur), 41700

Dos Hermanas, Spain, 2 Distrito Sanitario Sevilla-Sur, Alcalá de

Guadaira 41500, Spain, 3 Research Support Unit, Hospital Costa

del Sol, 29600 Marbella, Spain, 4 Department of Social

Psychology, Universidad de Sevilla, 41018 Sevilla, Spain, 5

Servicio Andaluz de Salud, Servicio de Ordenación Sanitaria,

41001 Sevilla, Spain, 6 Municipal Medical Services, 41927 Mairena

del Aljarafe, Spain, 7 Pain Treatment Unit, Centro de Salud

" Castilleja de la Cuesta, " 41950 Castilleja de la Cuesta, Spain.

Correspondence to: J Vas <jvas. Objectives:To

analyse the efficacy of AP as a complementary therapy to the

pharmacological treatment of osteoarthritis of the knee, with

respect to pain relief, reduction of stiffness, and increased physical

function during treatment; modifications in the consumption of

diclofenac during treatment; and changes in the patient's quality of

life. Design: Randomised, controlled, single blind trial, with blinded

evaluation and statistical analysis of results. Setting: Pain

management unit in a public primary care centre in southern Spain,

over a period of two years. Participants: 97 outpatients presenting

with osteoarthritis of the knee. Interventions: Patients were

randomly separated into two groups, one receiving AP plus

diclofenac (n = 48) and the other placebo AP plus diclofenac (n =

49). Main outcome measures: The clinical variables examined

included intensity of pain as measured by a visual analogue scale;

pain, stiffness, and physical function subscales of the Western

Ontario and McMaster Universities (WOMAC) osteoarthritis index;

dosage of diclofenac taken during treatment; and the profile of

quality of life in the chronically ill (PQLC) instrument, evaluated

before and after the treatment programme. Results: 88 patients

completed the trial. In the intention to treat analysis, the WOMAC

index presented a greater reduction in the intervention group than in

the control group (mean difference 23.9, 95% confidence interval

15.0 to 32.8) The reduction was greater in the subscale of

functional activity. The same result was observed in the pain visual

analogue scale, with a reduction of 26.6 (18.5 to 34.8). The PQLC

results indicate that AP treatment produces significant changes in

physical capability (P = 0.021) and psychological functioning (P =

0.046). Three patients reported bruising after the AP sessions.

Conclusions: AP plus diclofenac is more effective than placebo AP

plus diclofenac for the symptomatic treatment of osteoarthritis of

the knee.

 

 

Best regards,

 

Email: <

 

WORK : Teagasc, c/o 1 Esker Lawns, Lucan, Dublin, Ireland

Mobile: 353-; [in the Republic: 0]

 

HOME : 1 Esker Lawns, Lucan, Dublin, Ireland

Tel : 353-; [in the Republic: 0]

WWW : http://homepage.eircom.net/~progers/searchap.htm

 

Chinese Proverb: " Man who says it can't be done, should not interrupt man doing

it "

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