Guest guest Posted May 2, 2005 Report Share Posted May 2, 2005 Has anyone on this list anything to say about Chinese herbal medicine? If not, why not? This is a serious question. One which, I think, bears discussion. Why do we have comparatively so little to talk about vis a vis Chinese herbal medicine per se? So that I'm not just as guilty as the persons to whom I ask this question: In issue #1, 2005 of Tian Jin Zhong Yi Yao (Tianjin & Medicinals), Zhang Hai-feng, Yao Fang, Wang Wei-tao et al. describe the effects of an extract of Quan Xie (Buthus Martensis) on the progranulocyte HL-60 and its associated genes in acute promyelocytic leukemia. (According to an NIH Website, " The HL-60 cell line, derived from a single patient with acute promyelocytic leukemia, provides a unique in vitro model system for studying the cellular and molecular events involved in the proliferation and differentiation of normal and leukemic cells of the granulocyte/monocyte/macrophage lineage. " ) It was found that this extract could markedly increase the apoptosis (i.e., cell death) of HL-60. However, this effect was dose-dependent. At the highest concetration (10mg/mL), the proportion of apoptosis increased markedly, peaking at 21.44%. At mid and low doses, these proportions were only 12.56% and 9.47% respectively. Nevertheless, even this was marginally better than the 7.36% apoptosis in the control group. This treatment also markedly increased the expression of the P53 gene and decreased the expression of bel-2. Not only does this study suggest that an extract of Quan Xie has a beneficial effect on HL-60 death and associated gene expression, but it also once again underlines the importance of dose in the practice of Chinese medicine. Notice that the increase in effect from the high dosage was not a simple arthimetic progression. BTW, the extract used in this study was basically a water-based decoction with alcohol used as a preservative. Ten grams of scorpion were crushed and soaked in 100ml of water for 30 minutes. Then they were cooked at 100 degrees C two times. This liquid was spun in a centrifuge for 20 minutes at 1,000 rpm. Finally, it was cooked again at 100 degrees C for 20 minutes, then concentrated to 50% (I assume with alcohol) to eliminate any microbes. (If I read this section correctly.) Another BTW, the authors of this study say in their introduction that the main active ingredients in Quan Xie are scorpion toxins which are of four types. This suggests that, at least in Chinese medical oncology, the use of Quan Xie is a type of chemotherapy. Bob Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 2, 2005 Report Share Posted May 2, 2005 Interestingly, The new issue of the New England Journal of Acupuncture has an article on the treatment of a patient with a malignant brain tumor who was still alive and well five years after treatment with an herbal prescription containing qian xie. On another note, Bob, we need to make it easier for Western schools and practitioners to to CM journals in Chinese. Any possibility of giving a web link to a good supplier, or Blue Poppy serving as a subscription service? Thanks, On May 2, 2005, at 2:26 PM, Bob Flaws wrote: > Another BTW, the authors of this study say in their introduction that > the main active ingredients in Quan Xie are scorpion toxins which are > of four types. This suggests that, at least in Chinese medical > oncology, the use of Quan Xie is a type of chemotherapy. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 2, 2005 Report Share Posted May 2, 2005 an extract of Quan Xie (Buthus Martensis) on the progranulocyte HL-60 and >>>>Unfortunately these in vitro studies often have little to do with what actually occurs in patients Oakland, CA 94609 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 3, 2005 Report Share Posted May 3, 2005 , " " <zrosenbe@s...> wrote: > On another note, Bob, we need to make it easier for Western schools > and practitioners to to CM journals in Chinese. Any > possibility of giving a web link to a good supplier, or Blue Poppy > serving as a subscription service? Z'ev, take a look at www.wanfangdata.com They provide data on things Chinese, including Chinese medicine. They have, I believe, 79 Chinese medicial magazines online, including the better ones. They work with an annual subscription fee, and they already have several universities and libraries signed up. Mind you, the fee for a school is very steep. If you are an individual practitioner looking to read Chinese magazines, you may be able to negotiate a deal with them. I communicated with Danny Liu, who is in Beijing, and he seems to be a very nice guy dliu Regards, Tom. Quote Link to comment Share on other sites More sharing options...
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