Guest guest Posted June 25, 2005 Report Share Posted June 25, 2005 1: Fujimura T, Tamaki K, Iida S, Tanaka H, Ikedou H, Takamiya Y, Kato S, Tanaka A, Okuda S [A case of traditional herbal medicine-induced aristolochic acid nephropathy developing to end-stage renal failure] Nippon Jinzo Gakkai Shi 2005;47(4):474-80. A 48-year-old male was referred to our university hospital for severe azotemia with muscle cramp. He had been taking Chinese herbs as a traditional medicine to reduce hyperuricemia for about 9 months. Urinalysis showed trace proteinuria and hematuria without any casts. Renal glucosuria was also observed. In addition to azotemia, hyperchloremic metabolic acidosis and severe anemia were revealed. Hemodialysis was conducted and his general condition improved. A renal biopsy specimen revealed severe interstitial fibrosis and tubular atrophy with cellular degeneration. No remarkable glomerular changes were observed except for wrinkling of the basement membrane in a few glomeruli. Aristolochic acid was detected in the Chinese herbs, leading to the diagnosis of aristolochic acid nephropathy (AAN). His renal dysfunction was considered to be irreversible and he underwent maintenance hemodialysis. In Japan, AAN or Chinese herbs nephropathy decreased after an outbreak from 1995 to 2000. The public should be warned again that Chinese herbs, which are not permitted by the Japanese government, may contain aristolochic acid Oakland, CA 94609 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 25, 2005 Report Share Posted June 25, 2005 Alon, A bit of a stretch on the conclusion and an unnecessary, opinionated statement based upon one case is bad science. Wouldn't you agree? Mike W. Bowser, L Ac > " " <alonmarcus > > >Re: Re: another case >Sat, 25 Jun 2005 11:15:44 -0700 > > > > 1: Fujimura T, Tamaki K, Iida S, Tanaka H, Ikedou H, Takamiya Y, >Kato S, Tanaka A, Okuda S > > [A case of traditional herbal medicine-induced aristolochic acid >nephropathy developing to end-stage renal failure] > Nippon Jinzo Gakkai Shi 2005;47(4):474-80. > A 48-year-old male was referred to our university hospital for >severe azotemia with muscle cramp. He had been taking Chinese herbs as a >traditional medicine to reduce hyperuricemia for about 9 months. Urinalysis >showed trace proteinuria and hematuria without any casts. Renal glucosuria >was also observed. In addition to azotemia, hyperchloremic metabolic >acidosis and severe anemia were revealed. Hemodialysis was conducted and >his general condition improved. A renal biopsy specimen revealed severe >interstitial fibrosis and tubular atrophy with cellular degeneration. No >remarkable glomerular changes were observed except for wrinkling of the >basement membrane in a few glomeruli. Aristolochic acid was detected in the >Chinese herbs, leading to the diagnosis of aristolochic acid nephropathy >(AAN). His renal dysfunction was considered to be irreversible and he >underwent maintenance hemodialysis. In Japan, AAN or Chinese herbs >nephropathy decreased after an outbreak from 1995 to 2000. The public >should be warned again that Chinese herbs, which are not permitted by the >Japanese government, may contain aristolochic acid > > > > >Oakland, CA 94609 > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 25, 2005 Report Share Posted June 25, 2005 > > > On Behalf Of The public should be warned again that Chinese herbs, which are not > permitted by the Japanese government... > [Jason] I don't get this last sentence??? Not permitted?? -Jason Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 25, 2005 Report Share Posted June 25, 2005 A bit of a stretch on the conclusion and an unnecessary, opinionated statement based upon one case is bad science. Wouldn't you agree? >>>>It sounds a little confusing, if speaking of particular herb may be appropriate Oakland, CA 94609 Quote Link to comment Share on other sites More sharing options...
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