Awesome Database of Herbs, Formulas and active compounds in Cancer Therapy

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Hi All,

 

U Michigan has an awesome database of Herbs, Formulas and active

compounds in Cancer Therapy.

 

Researchers in Government & Academic institutions can apply for free

access but one must register from a bona-fide email address from a

recognised institution.

 

To register, go to http://sw16.im.med.umich.edu/chmis-c/ or email Dr.

Xueliang Fang <xueliang.

 

Xueliang Fang, Lei Shao, Hui Zhang, and Shaomeng Wang* (2005)

CHMIS-C: A Comprehensive Herbal Medicine Information System for

Cancer. J. Med. Chem., 48 (5), 1481 -1488, 2005. 10.1021/jm049838d

S0022-2623(04)09838-3. Web Release February 9, 2005

Copyright 2005 American Chemical Society Departments of Internal

Medicine and Medicinal Chemistry and University of Michigan

Comprehensive Cancer Center, University of Michigan, 1500 East

Medical Center Drive, Ann Arbor, Michigan 48109-0934 Received

February 24, 2004 Abstract: A comprehensive herbal medicine

information system for cancer (CHMIS-C) has been developed. The

current version of the database integrates information on more than 200

anticancer herbal recipes that have been used for the treatment of

different types of cancer in clinic, 900 individual ingredients, and 8500

small organic molecules isolated from herbal medicines. Furthermore,

subsidiary databases of literature references and molecular targets have

been constructed. A number of web-based searching tools have been

developed and integrated into the information system for efficient data

mining. The compounds in the database have been linked to the

corresponding entries in the National Cancer Institute's database, and to

a database of drugs approved by the U.S. Food and Drug

Administration. This paper provides a description of the individual

subsidiary databases, integration of the entire database, and data

mining tools. We demonstrate that this comprehensive information

system may be used as an effective informatics tool for

anticancer drug discovery.

 

Below are the TOP 50 Herbs in the database used in Formulas for

cancer therapy:

[From http://sw16.im.med.umich.edu/chmis-c/mine/topingredient.jsp? ]

 

Use the vertical line (|) as a field separator to convert the text below to a

6-column table

 

_Rank|_Frequency|_Hb PinYin Name (Aka Other Pinyin Names)|_Hb

Latin Name|_Hb English Name|_Used in Cancer Type

 

1|145|Baihuasheshecao (Sheshecao, Zhuyecai, Shelicao)|Hb Hedyotis

Diffusae|Spreading Hedyotis Hb|Digestive tract, LV, Lymphoma, Cervix,

Larynx, SI, LI, Anus, Chorioepithelioma

 

2|129|Xiakucao (Denglongtoucao, Bangzhutoucao, Datouhua,

Langtoucao, Xiakuqiu, Bangtoucao, Baihuacao (Hebei), Fengwocao

(Fujian))|Spica Prunellae|Common Selfheal Fruit-Spike|Uterus, Thyroid,

Mammary, Lymphoma

 

3|128|Banzhilian (Bingtoucao, Yashuacao, Tongjincao, Jinwacao)|Hb

Scutellariae Barbatae|Barbed Skullcap Hb|Cervix, LV

 

4|94|Danggui (Qingui, Yungui)|Rx Angelicae Sinensis|Chinese

Angelica|Sarcoma

 

5|80|Jinyinhua (Erbaohua, Erhua, Shuanghua, Yinhua, Rendonghua)|Fl

Lonicerae|Honeysuckle Fl|Nose & Throat, Uterus, Cervix, Vagina

 

6|80|Haizao (Luoshou, Hailuo, Wucai, Haidaihua, Yangqicai,

Xiaoyehaizao, Lujiaojian (Liaoning;Shandong), Haidamai (Zhejiang),

Yucao (Guangdong), Liujiaocai (Fujian), Huxupao (Fujian), Haihaozi,

Dayehaizao, Sanjiaozao, Maweizao, Dahaozi (Liaoning), Haigencai

(Shandong))|Sargassum|Seaweed|Sarcoma, Abdomen

 

7|77|Fuling (Wanlingjin, Wanlinggui, Fusi, Yuling, Futu,

Yunling)|Poria|Indian Bread|Nourish

 

8|73|Danshen (Xueshenggen, Chishen, Xueshen, Honggen,

Muyangru)|Rx Salviae Miltiorrhizae|Danshen Rx|Abdomen, Melanoma,

LV

 

9|71|Dangshen (Xidang, Ludang, Jingdangshen, Dongdang, Xidang,

Ludang, Tiaodang, Huangshen, Shitoushen, Zhonglingcao)|Rx

Codonopsis|Tangshen|LU

 

10|67|Gancao (Micao, Shenggancao, Bangcao, Tiancaogen)|Rx

Glycyrrhizae|Liquorice Rx|ST, Tongue, Larynx, LV

 

11|62|Kunbu (Jiangbaicai)|Thallus Laminariae|Kelp|Thyroid,

Oesophagus, Uterus, Lymphoma, LU, LV, Mammary

 

12|62|Shengdi (Disui, Yuandisheng, Niunaizi, Poponai, Gounaizi,

Shanbaicai, Jiuhuhua, Shanyugen)|Rx Rehmanniae recens|Rehmannia

Rx, fresh|?

 

13|59|Wugong (Tianlong, Baijiao)|Scolopendra|Centipede|ST, Skin,

Abdomen, Cervix

 

14|58|Yiyiren (Yiren, Yimi, Miren, Liugu, Chuangu, Caozhuzi, Putizi,

Niaodangzhu (Sichuan))|S Coicis |Coix S|?

 

15|56|Taoren (Maotaoren, Baitaoren, Biantaoren, Dataoren)|S

Persicae|Peach S|Oesophagus, ST, LU

 

16|54|Muxiang (Yunmuxiang, Guangmuxiang)|Rx Aucklandiae|Costus

Rx|Nourish

 

17|50|Xionghuang (Huangjinshi, Shihuang, Tianyangshi, Huangshi,

Jiguanshi)|Realgar|Realgar|Cervix, Skin, Mammary, Leukemia,

Oesophagus, ST

 

18|49|Chishao (Huangshao, Boshao, Shanshaoyao, Chishaoyao,

Mushaoyao, Hongshaoyao, Choumudangen)|Rx Paeoniae Rubra|Red

Peony Rx|General, LV

 

19|48|Woshu (?)|?|?|?

 

20|46|Chenpi (Jupi)|Pc Citri Reticulatae |Tangerine Pc|?

 

21|44|Bingpian (Hechenglonglao)|Borneolum Syntheticum|Synthetic

Borneol|Cervix, Skin, Lymphoma, Larynx

 

22|44|Baizhu (Yuzhu, Dongzhu, Baishu, Yuzhu, Dongzhu, Yuqianbaizhu,

Shanji)|Rz Atractylodis Macrocephalae|Largehead Atractylodes Rz|ST,

Abdomen

 

23|43|Huangqi (Mianhuangqi)|Rx Astragali|Milkvetch Rx|Melanoma, LV,

LU, Cervix

 

24|42|Sanleng (Jingsanleng)|Rz Sparganii|Common Burreed

Tuber|Nourish

 

25|41|Quanxie (Quanchong, Fubeichong,

Danweichong)|Scorpio|Scorpion|LU, ST, LV, Lymphoma, Mammary,

Oesophagus

 

26|41|Zicao (Yingzicao, Dazicao, Hongtiaozicao)|Rx

Lithospermi|Gromwell Rx|Chorioepithelioma, Leukemia, LU, LV, Cervix,

ST, Mammary

 

27|40|Shandougen (Guangdougen, Kudougen, Nandougen,

Yanhuanglian)|Rx Sophorae Tonkinensis|Vietnamese Sophora

Rx|Cervix

 

28|40|Ruxiang (Xunluxiang, Rutouxiang, Xixiang, Molexiang,

Duojialuoxiang)|Olibanum|Olibanum|Sarcoma

 

29|38|Baishao (Hangshao, Haoshao)|Rx Paeoniae Alba |White Paeony

Rx|?

 

30|37|Dahuang (Nandahuang)|Rx+Rz Rhei|Rhubarb|Melanoma,

Mammary, Abdomen, Oesophagus

 

31|36|Xuanshen (Yuanshen, Zhexuanshen, Heishen, Wuyuanshen)|Rx

Scrophulariae|Figwort Rx|Nourish

 

32|36|Moyao ()|Myrrh |Myrrha |?

 

33|36|Longkui (Yeqie, Yehaijiao, Kukui, Yelahu, Tianluncao)|Hb Solani

Nigri|Black Nightshade Hb|LU, ST, LV, BL, Digestive tract

 

34|36|Tianhuafen (Huafen, Gualougen, Yadanguagen)|Rx

Trichosanthis|Snakegourd Rx|Chorioepithelioma

 

35|35|Shijianchuan (Shidachuan, Zishen, Yuexiahong)|Hb Salviae

Chinensis|Chinese Sage Hb|Oesophagus, ST, LU

 

36|33|Maidong (Yanjiecao, Maimendong, Maimendong, Yanjiecao,

Hangmaidong, Chuanmaidong, Cundong, Xiaomaimengdong,

Dimaidong (Sichuan))|Rx Ophiopogonis|Dwarf Lilyturf Tuber|Nourish

 

37|33|Xiangfu (Shacaogen, Sanlengcao)|Rz Cyperi|Nutgrass Galingale

Rz|Colon, Rectum

 

38|33|Huangyaozi (Huangduzi, Jinxiandiaodan, Huangjinshanyao,

Lingyuzishuyu)|Rz Dioscoreae Bulbiferae|Airpotato Yam

Rz|Oesophagus, Thyroid, ST, SI, LI, LU, Cervix

 

39|33|Fengfang (Lufengfang, Mafengwo, Hufengke, Huangfengwo,

Mafengbao, Yefengfang, Zhifengfang)|Nidus Vespae |Honeycomb|?

 

40|33|Mihoutaogen (Tengligen, Yangtaogen, Hongtengligen)|Rx

Actinidiae Chinensis|Yangtao Actinidia Rx|Nose & Throat, Oesophagus,

LV, ST, Cervix

 

41|33|Huanglian (Tuhuanglian, Weilian, Chuanlian, Jizhualian)|Rz

Coptidis|Coptis Rz|LV, Oesophagus

 

42|32|Yujin (Jianghuang, Maojianghuang)|Rx Curcumae|Turmeric Rx-

Tuber|LV, Pancreas, ST, Oesophagus, SI, LI,

 

43|32|Pengsha (Yueshi, Xiyueshi, Pensha)|Borax |Borax|?

 

44|32|Shexiang (Dangmenzi, Shejixiang, Siweichou, Lazi,

Xiangjizi)|Moschus|Musk|LV, Nose & Throat, Mammary, Skin, Abdomen

 

45|31|Chuanshanjia (Linglijia, Shanjia, Jiapian, Qianlijia, Longli)|Squama

Manis|Pangolin Scales|Mammary, Nose & Throat, SI, LI, Leukemia

 

46|31|Yejuhua (Yehuangjuhua, Kuyi, Shanjuhua, Ganjuhua)|Fl

Chrysanthemi Indici|Wild Chrysahthemum Fl|Nose & Throat, Mouth, LV,

Pancreas, Lymphoma, Leukemia, Skin

 

47|30|Honghua (Caohonghua, Cihonghua, Duhonghua, Jinhonghua)|Fl

Carthami|Safflower|ST, LV, Nose & Throat, Uterus, Ovary

 

48|30|Muli (Hailizi, Lihe, Lifang)|Concha Ostreae|Oyster Shell|Mammary,

Lymphoma, ST, LU

 

49|30|Baiying (Baimaoteng, Baihulu, Maoxiucai, Manjia, Beifengteng,

Baimaoteng, Shuyangquan, Paifengteng, Baicao (Guangdong),

Huluteng (Fujian), Maohulu (Jiangxi), Maoxiucai (Sichuan),

Yingyaodouzi (Shandong))|Hb Solani Lyrati|Bittersweet Hb|Cervix, LU,

Vocal, Bone, ST, Oesophagus, LV, Larynx

 

50|30|Chuanlianzi (Chuanlianshi, Jinlingzi, Kulianzi)|Fr

Toosendan|Szechwan Chinaberry Fr|Cervix

 

 

 

 

 

Best regards,

 

 

Tel: (H): +353-(0) or (M): +353-(0)

 

 

 

 

Ireland.

Tel: (W): +353-(0) or (M): +353-(0)

 

 

 

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