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Antioxidants may interfere with cholesterol drugs. A 1-year study of

153 patients has found that supplements of vitamin C, vitamin E, beta-

carotene and selenium may interfere with the ability of simvastatin

(Zocor) and niacin to raise the HDL levels of patients with

abnormally low HDL levels. The patients receiving antioxidants and

drugs had an average HDL increase of 18%, whereas the patients who

received drugs alone has a 25% increase. However, HDL2-C, an HDL

component thought to account for much of HDL's cardioprotective

benefit, rose by 42% with drugs alone but was unchanged in patients

who also received antioxidants. [Cheung MC and others. Antioxidant

supplements block the response of HDL to Simvastatin-niacin therapy

in patients with coronary artery disease and low HDL.

Arteriosclerosis, Thrombosis, and Vascular Biology 21:1320, 2001.]

Although the study was small and has not been replicated, it casts

further doubt on the value of antioxidant supplementation.

 

 

 

Chinese Herbs

 

 

 

 

 

 

 

 

 

 

 

 

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you can never win

 

 

 

 

Oakland, CA 94609

 

 

-

cha

Friday, November 25, 2005 7:47 AM

disturbing

 

 

Antioxidants may interfere with cholesterol drugs. A 1-year study of

153 patients has found that supplements of vitamin C, vitamin E, beta-

carotene and selenium may interfere with the ability of simvastatin

(Zocor) and niacin to raise the HDL levels of patients with

abnormally low HDL levels. The patients receiving antioxidants and

drugs had an average HDL increase of 18%, whereas the patients who

received drugs alone has a 25% increase. However, HDL2-C, an HDL

component thought to account for much of HDL's cardioprotective

benefit, rose by 42% with drugs alone but was unchanged in patients

who also received antioxidants. [Cheung MC and others. Antioxidant

supplements block the response of HDL to Simvastatin-niacin therapy

in patients with coronary artery disease and low HDL.

Arteriosclerosis, Thrombosis, and Vascular Biology 21:1320, 2001.]

Although the study was small and has not been replicated, it casts

further doubt on the value of antioxidant supplementation.

 

 

Chinese Herbs

 

 

 

 

 

 

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Share on other sites

, " " <alonmarcus@w...>

wrote:

>

> you can never win

>

>

 

Or there is no free lunch. It is just a reminder that there is a lot that we

can't know

without controlled studies (a point about which you and I have long agreed). A

reminder

that even longterm use of chinese herbs in combination with drugs is not even

remotely

proven safe. When we talk about drug/herb interactions, we are usually

referring to

something obvious like getting diarrhea or a headache. But subtler things like

alterations

in cholesterol are typically silent killers and we don't know until its too

late. We nned to

always keep in mind that despite the lack of any hard data to question the use

of

combined herb/drug therapy, we in new territory and this could easily come back

to bite

us in the butts someday. Many chinese herbs have antioxidant properties, thus

we need to

be very careful when prescribing any herbs with any drugs.

 

Heart disease is still the number one killer in America and will be for a long

time to come.

Anything an herbalist does that increases the risk of a heart attack is a

lawsuit waiting to

happen in litiginous america. My guess is that if you get sued under such a

scenario, your

malpractice carrier will drop you like a hot potato. This is one of many

reasons I have

recently been advocating the use of chinese herbs for short term use in acute

conditions

or to control symptoms. The mere fact that the Chinese temselves have used

certain

herbs longterm also does not guarantee their safety under these conditions nor

do the

claims of native chinese docs that the whole issue is a red herring. Most

chinese docs

know little or nothing about pharmacology and their opinions on this topic of

drug/herb

interaction is really baseless.

 

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Todd

The other side of the coin is that oxidation of cholesterol may be very

significant.

As far as herbs, while many will disagree i do not think we have much of any

data on long term use. While the Chinese did have incredible observation

abilities much of what we know today simply was not available

 

 

 

 

Oakland, CA 94609

 

 

-

Friday, November 25, 2005 3:00 PM

Re: disturbing

 

 

, " " <alonmarcus@w...>

wrote:

>

> you can never win

>

>

 

Or there is no free lunch. It is just a reminder that there is a lot that we

can't know

without controlled studies (a point about which you and I have long agreed).

A reminder

that even longterm use of chinese herbs in combination with drugs is not even

remotely

proven safe. When we talk about drug/herb interactions, we are usually

referring to

something obvious like getting diarrhea or a headache. But subtler things

like alterations

in cholesterol are typically silent killers and we don't know until its too

late. We nned to

always keep in mind that despite the lack of any hard data to question the use

of

combined herb/drug therapy, we in new territory and this could easily come

back to bite

us in the butts someday. Many chinese herbs have antioxidant properties, thus

we need to

be very careful when prescribing any herbs with any drugs.

 

Heart disease is still the number one killer in America and will be for a long

time to come.

Anything an herbalist does that increases the risk of a heart attack is a

lawsuit waiting to

happen in litiginous america. My guess is that if you get sued under such a

scenario, your

malpractice carrier will drop you like a hot potato. This is one of many

reasons I have

recently been advocating the use of chinese herbs for short term use in acute

conditions

or to control symptoms. The mere fact that the Chinese temselves have used

certain

herbs longterm also does not guarantee their safety under these conditions nor

do the

claims of native chinese docs that the whole issue is a red herring. Most

chinese docs

know little or nothing about pharmacology and their opinions on this topic of

drug/herb

interaction is really baseless.

 

Todd

 

 

 

 

 

Chinese Herbal Medicine offers various professional services, including board

approved continuing education classes, an annual conference and a free

discussion forum in Chinese Herbal Medicine.

 

 

 

 

 

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  • 1 month later...

Im all for keeping all that we know today in mind, but what about some

more emphasis in our training/practice on developing those

" incredible observation abilities " as well? Surely the two combined

are the best defence against coming to what may prove to be out of

proportion conclusions on things...

 

, " "

<alonmarcus@w...> wrote:

>

 

> The other side of the coin is that oxidation of cholesterol may be

very significant.

> As far as herbs, while many will disagree i do not think we have

much of any data on long term use. While the Chinese did have

incredible observation abilities much of what we know today simply was

not available

>

>

>

>

> Oakland, CA 94609

>

>

> -

>

>

> Friday, November 25, 2005 3:00 PM

> Re: disturbing

>

>

> , " "

<alonmarcus@w...>

> wrote:

> >

> > you can never win

> >

> >

>

> Or there is no free lunch. It is just a reminder that there is a

lot that we can't know

> without controlled studies (a point about which you and I have

long agreed). A reminder

> that even longterm use of chinese herbs in combination with drugs

is not even remotely

> proven safe. When we talk about drug/herb interactions, we are

usually referring to

> something obvious like getting diarrhea or a headache. But

subtler things like alterations

> in cholesterol are typically silent killers and we don't know

until its too late. We nned to

> always keep in mind that despite the lack of any hard data to

question the use of

> combined herb/drug therapy, we in new territory and this could

easily come back to bite

> us in the butts someday. Many chinese herbs have antioxidant

properties, thus we need to

> be very careful when prescribing any herbs with any drugs.

>

> Heart disease is still the number one killer in America and will

be for a long time to come.

> Anything an herbalist does that increases the risk of a heart

attack is a lawsuit waiting to

> happen in litiginous america. My guess is that if you get sued

under such a scenario, your

> malpractice carrier will drop you like a hot potato. This is one

of many reasons I have

> recently been advocating the use of chinese herbs for short term

use in acute conditions

> or to control symptoms. The mere fact that the Chinese temselves

have used certain

> herbs longterm also does not guarantee their safety under these

conditions nor do the

> claims of native chinese docs that the whole issue is a red

herring. Most chinese docs

> know little or nothing about pharmacology and their opinions on

this topic of drug/herb

> interaction is really baseless.

>

> Todd

>

>

>

>

>

> Chinese Herbal Medicine offers various professional services,

including board approved continuing education classes, an annual

conference and a free discussion forum in Chinese Herbal Medicine.

>

>

>

>

>

>

>

Link to comment
Share on other sites

Wow, have you been going over old posts?

 

 

 

 

Oakland, CA 94609

 

 

-

bianzhengnazi

Monday, January 23, 2006 4:54 PM

Re: disturbing

 

 

Im all for keeping all that we know today in mind, but what about some

more emphasis in our training/practice on developing those

" incredible observation abilities " as well? Surely the two combined

are the best defence against coming to what may prove to be out of

proportion conclusions on things...

 

, " "

<alonmarcus@w...> wrote:

>

> The other side of the coin is that oxidation of cholesterol may be

very significant.

> As far as herbs, while many will disagree i do not think we have

much of any data on long term use. While the Chinese did have

incredible observation abilities much of what we know today simply was

not available

>

>

>

>

> Oakland, CA 94609

>

>

> -

>

>

> Friday, November 25, 2005 3:00 PM

> Re: disturbing

>

>

> , " "

<alonmarcus@w...>

> wrote:

> >

> > you can never win

> >

> >

>

> Or there is no free lunch. It is just a reminder that there is a

lot that we can't know

> without controlled studies (a point about which you and I have

long agreed). A reminder

> that even longterm use of chinese herbs in combination with drugs

is not even remotely

> proven safe. When we talk about drug/herb interactions, we are

usually referring to

> something obvious like getting diarrhea or a headache. But

subtler things like alterations

> in cholesterol are typically silent killers and we don't know

until its too late. We nned to

> always keep in mind that despite the lack of any hard data to

question the use of

> combined herb/drug therapy, we in new territory and this could

easily come back to bite

> us in the butts someday. Many chinese herbs have antioxidant

properties, thus we need to

> be very careful when prescribing any herbs with any drugs.

>

> Heart disease is still the number one killer in America and will

be for a long time to come.

> Anything an herbalist does that increases the risk of a heart

attack is a lawsuit waiting to

> happen in litiginous america. My guess is that if you get sued

under such a scenario, your

> malpractice carrier will drop you like a hot potato. This is one

of many reasons I have

> recently been advocating the use of chinese herbs for short term

use in acute conditions

> or to control symptoms. The mere fact that the Chinese temselves

have used certain

> herbs longterm also does not guarantee their safety under these

conditions nor do the

> claims of native chinese docs that the whole issue is a red

herring. Most chinese docs

> know little or nothing about pharmacology and their opinions on

this topic of drug/herb

> interaction is really baseless.

>

> Todd

>

>

>

>

>

> Chinese Herbal Medicine offers various professional services,

including board approved continuing education classes, an annual

conference and a free discussion forum in Chinese Herbal Medicine.

>

>

>

>

>

>

>

Link to comment
Share on other sites

Yeah, sorry :P!

 

, " "

<alonmarcus@w...> wrote:

>

> Wow, have you been going over old posts?

>

>

>

>

> Oakland, CA 94609

>

>

> -

> bianzhengnazi

>

> Monday, January 23, 2006 4:54 PM

> Re: disturbing

>

>

> Im all for keeping all that we know today in mind, but what about some

> more emphasis in our training/practice on developing those

> " incredible observation abilities " as well? Surely the two combined

> are the best defence against coming to what may prove to be out of

> proportion conclusions on things...

>

> , " "

> <alonmarcus@w...> wrote:

> >

>

> > The other side of the coin is that oxidation of cholesterol may be

> very significant.

> > As far as herbs, while many will disagree i do not think we have

> much of any data on long term use. While the Chinese did have

> incredible observation abilities much of what we know today simply was

> not available

> >

> >

> >

> >

> > Oakland, CA 94609

> >

> >

> > -

> >

> >

> > Friday, November 25, 2005 3:00 PM

> > Re: disturbing

> >

> >

> > , " "

> <alonmarcus@w...>

> > wrote:

> > >

> > > you can never win

> > >

> > >

> >

> > Or there is no free lunch. It is just a reminder that there is a

> lot that we can't know

> > without controlled studies (a point about which you and I have

> long agreed). A reminder

> > that even longterm use of chinese herbs in combination with drugs

> is not even remotely

> > proven safe. When we talk about drug/herb interactions, we are

> usually referring to

> > something obvious like getting diarrhea or a headache. But

> subtler things like alterations

> > in cholesterol are typically silent killers and we don't know

> until its too late. We nned to

> > always keep in mind that despite the lack of any hard data to

> question the use of

> > combined herb/drug therapy, we in new territory and this could

> easily come back to bite

> > us in the butts someday. Many chinese herbs have antioxidant

> properties, thus we need to

> > be very careful when prescribing any herbs with any drugs.

> >

> > Heart disease is still the number one killer in America and will

> be for a long time to come.

> > Anything an herbalist does that increases the risk of a heart

> attack is a lawsuit waiting to

> > happen in litiginous america. My guess is that if you get sued

> under such a scenario, your

> > malpractice carrier will drop you like a hot potato. This is one

> of many reasons I have

> > recently been advocating the use of chinese herbs for short term

> use in acute conditions

> > or to control symptoms. The mere fact that the Chinese temselves

> have used certain

> > herbs longterm also does not guarantee their safety under these

> conditions nor do the

> > claims of native chinese docs that the whole issue is a red

> herring. Most chinese docs

> > know little or nothing about pharmacology and their opinions on

> this topic of drug/herb

> > interaction is really baseless.

> >

> > Todd

> >

> >

> >

> >

> >

> > Chinese Herbal Medicine offers various professional services,

> including board approved continuing education classes, an annual

> conference and a free discussion forum in Chinese Herbal Medicine.

> >

> >

> >

> >

> >

> >

> >

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