multiple sclerosis

[Guest guest]

Does anyone know what is is Bushen Gu Sui tablet and if they are available in

the US?

 

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2001 Jan;21(1):10-4.

[Clinical and experimental study on multiple sclerosis with bushen gusui tablet]

 

[Article in Chinese]

 

Liu XY, Sun Y.

 

Xiyuan Hospital, China Academy of TCM, Beijing 100091.

 

OBJECTIVE: To observe the therapeutic effect of Bushen Gusui tablet (BSGS) in

treating

multiple sclerosis (MS) and its effects on experimental allergic

encephalomyelitis (EAE) in

guinea pigs. METHODS: Forty-three MS patients were treated with BSGS and their

clinical

symptoms, signs of nerve function, recurrent frequency, evoked potential and

changes in

magnetic resonance imaging (MRI) were observed. The EAE model of guinea pigs was

induced by homogenate of rabbit spinal cord and complete Freund's adjuvant

(CFA), the

animals were treated with BSGS and compared with prednisone acetate, which was

served

as control. The mortality and pathomorphology of EAE animals were observed. The

contents of serum interleukin-2 (IL-2), interleukin-6 (IL-6), tumor necrosis

factor (TNF) as

well as myelin basic protein (MBP) were determined. RESULTS: BSGS could improve

symptoms and signs of MS patients and reduce recurrent frequency. The total

effective

rate was 88.37%. High dose BSGS could obviously reduce incidence of EAE, inhibit

inflammatory reaction of brain and spinal cord as well as demyelination, and

simultaneously inhibit the activity of serum IL-2, IL-6, TNF and MBP, in

comparing with

model group (P < 0.01). There were insignificant difference as compared with

prednisone

acetate group (P > 0.05). CONCLUSION: BSGS had certain effect on both MS

patients and

EAE model animals, which indicated that it was worth further studying and

clinical

application.