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Ingredients of FAHF-1 (Antiallergic formula)

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Hi Alex, & All,

 

Alex Berk wrote:

> ...Herbal formula silences peanut allergy in mice ... What is in this

> formula? In looking around pubmed I found the difference between FAHF-1

> and FAHF-2 is the removal of xixin and fuzi but there is no listing

> of the herbs. Does anyone know what it is?

 

http://tinyurl.com/qxfmj says:

Herbs that fight nut allergy disclosed, By Terry Murray

 

NEW YORK ¨C The formula has been revealed, 12 months later¡ªthe

names of 11 Chinese herbs reported at the AAAAI meeting last year to

have a striking effect on peanut allergy in a mouse model.

 

Dr. Xiu-Min Li, assistant professor of pediatrics and clinical immunology

at the Mount Sinai School of Medicine here, told the conference last

year that the herbal formula reduced peanut-specific IgE levels in the

mice by more than 30% and protected the animals from anaphylaxis.

However, neither she nor another investigator on the project would

reveal the contents of the formulation (see Medical Post, April 17,

2001).

 

But in a seminar on alternative therapies in food allergy at this year's

conference, Dr. Li named the contents. She listed the components of

FAHF-1 (or food allergy herbal formula 1) first by their traditional

Chinese medicine designation (in Pinyin), followed by the equivalent

pharmaceutical name:

 

Lingzhi (Chi), or Ganoderma lucidum;

Fuzi (zhi), or Radix lateralis aconiti carmicaeli praeparata;

Wumei, or Fructus pruni mume;

Chuanjiao, or Pericarpium zanthoxyli bungeani;

Xixin, or Herba cum radice asari;

Huanglian (Chuan), or Rhizoma coptidis;

Huangbai, or Cortex phellodendri;

Ganjiang, or Rhizoma zingiberis officinalis;

Guizhi, or Ramulus cinnamomi cassiae;

Renshen (Hong), or Radix ginseng; and

Danggui (shen), or Corpus radix angelicae sinensis.

 

The Mt. Sinai researchers are working to standardize FAHF-1, to

explore the way in which it suppresses allergic reactions and to

determine the best combination of the 11 ingredients, Dr. Li said.

They have also moved " one step closer to clinical study " by starting to

evaluate FAHF-1 with human mucosal lymphocytes from four milk-

allergic patients, she added. But she said only that in cell culture, FAHF-

1 produced a " clear reduction " in proliferation and in IL-4 and IL-13, but

did not alter interferon-gamma production.

 

The ingredients, above, refer to FAHF-1. The version used in the US

trial (FAHF-2) removed Xixin & Fuzi, but that removel did not reduce the

anti-allergic effect.

http://nccam.nih.gov/news/newsletter/2006_winter/roundup.htm

 

Best regards,

Phil

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