Dai-kenchu-to, improves stasis of patients with total gastrectomy and jejunal pouch interposition

[Guest guest]

Hi All,

 

Dai-kenchu-to (Japanese) = Da-Jian-Zhong-Tang (Chinese)

 

Endo S, Nishida T, Nishikawa K, Nakajima K, Hasegawa J, Kitagawa T, Ito

T, Matsuda H. Dai-kenchu-to, a Chinese herbal medicine, improves stasis

of patients with total gastrectomy and jejunal pouch interposition. Am J

Surg. 2006 Jul;192(1):9-13. Department of Surgery, E1, Osaka University

Graduate School of Medicine, 2-2 Yamadaoka, Suita-shi, Osaka, 565-0871

Japan. BACKGROUND: Intestinal motility after gastric surgery frequently is

disturbed and results in postoperative intestinal symptoms and poor quality

of life (QOL). The purpose of this study was to examine the effects of Dai-

kenchu-to on intestinal motility and postoperative QOL of patients.

METHODS: Seventeen patients who underwent total gastrectomy with

jejunal pouch interposition for gastric cancer in the Department of Surgery

of Osaka University Medical Hospital were enrolled. The patients were

assigned randomly to the cross-over study with or without 15 g/d of Dai-

kenchu-to. Questionnaires and emptying tests using (111)In-labeled liquid

and (99m)Tc-labeled solid test meal were performed at the end of each

treatment period. A manometric study was performed in 6 patients to

measure contractile activity with or without Dai-kenchu-to. RESULTS:

Stasis-related symptoms were reduced significantly by Dai-kenchu-to (P =

..032). In the emptying test, Dai-kenchu-to accelerated emptying of both

liquid (P < .01) and solid (P = .015) meals from the pouch. The pouch

showed bursts of contractions, which were increased significantly by oral

intake of Dai-kenchu-to (P = .028). CONCLUSIONS: Dai-kenchu-to

increased intestinal motility and decreased postoperative symptoms of

patients with total gastrectomy with jejunal pouch interposition. PMID:

16769267 [PubMed - in process]

 

Best regards,