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Health: Chronic Cough - Iron Deficiency Could be to Blame

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A study involving but 16 women is not all that scientific .. but 100%

results sorta offsets the low number in the test group. Butch

 

 

Chronic Cough? Iron Deficiency Could be to Blame

 

Tue Oct 23, 2007 4:55pm EDT

 

By Julie Steenhuysen

 

CHICAGO (Reuters) - Instead of cough drops, some women may need to reach for

an iron supplement to treat that pesky cough, Italian researchers said on

Tuesday.

 

The study, presented at the scientific meeting of the American College of

Chest Physicians in Chicago, suggests iron deficiency may help explain why

some otherwise healthy, non-smoking women had persistent coughs.

 

Tests on women with chronic coughs and iron deficiency showed that a simple

iron supplement often cleared up the cough, said Dr. Caterina Bucca of the

University of Turin and colleagues.

 

Bucca said women also are more likely than men to suffer from otherwise

unexplained chronic coughs.

 

" We put the two together, " Bucca said in a telephone interview. " Cough is

much more frequent in women and iron deficiency is very frequent in women

due to pregnancy and menses. "

 

In addition, immune function can be affected by iron deficiency, which is

defined as having low iron levels, sometimes to the point of anemia.

 

Bucca and colleagues studied 16 women with chronic cough who were found to

have normal lung function, with no signs of asthma or other respiratory

disease and no evidence of acid stomach reflux that could explain their

coughing.

 

All had iron deficiencies.

 

And they all had signs of swelling in the back of the mouth and red,

inflamed mucous membranes. Their vocal cords were also very sensitive,

making them cough and choke easily, such as after vigorous laughing.

 

Bucca gave these women iron supplements to improve their iron stores. When

these had normalized -- after about two months -- they were checked again.

 

After iron supplementation, coughing and signs of inflammation in the mouth

and vocal cords were improved or completely resolved.

 

" I found the hypersensitivity was nearly gone or vastly improved in all of

the women, " Bucca said.

 

Because iron helps regulate the production of proteins in the immune system

that control inflammation, an iron deficiency might make the upper airway

more prone to inflammation, leading to this chronic cough, Bucca reasoned.

 

She plans to study this association further, but she urges doctors who are

stumped by women patients with chronic coughs to check for iron deficiency.

 

© Reuters 2006. All rights reserved

 

 

 

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