OT: St. John's Wort oil and wound healing

[Guest guest]

Since many of us use SJW oil in our herbal preparations, this is a nice bit of

news to share.

 

http://www.liebertonline.com/doi/abs/10.1089/acm.2009.0317

 

The Journal of Alternative and Complementary Medicine

The Effect of Hypericum perforatum on the Wound Healing and Scar of Cesarean

To cite this article:

Sareh Samadi, Talat Khadivzadeh, Ahmad Emami, Naser Sanjar Moosavi, Mohsen

Tafaghodi, Hamid Reza Behnam. The Journal of Alternative and Complementary

Medicine. January 2010, 16(1): 113-117. doi:10.1089/acm.2009.0317.

Published in Volume: 16 Issue 1: January 27, 2010

Online Ahead of Print: January 11, 2010

Full Text: • HTML • PDF for printing (79.5 KB) • PDF w/ links (95.9 KB)

 

 

Sareh Samadi, M.Sc.,1

Talat Khadivzadeh, M.Sc.,2

Ahmad Emami, Ph.D.,3

Naser Sanjar Moosavi,6

Mohsen Tafaghodi, Ph.D.,4 and

Hamid Reza Behnam, M.Sc.5

1Mashhad University of Medical Sciences, Mashhad, Iran.

2Women's Health Research Center and School of Nursing and Midwifery, Mashhad,

Iran.

3Department of Pharmacognosy, Mashhad University of Medical Sciences, Mashhad,

Iran.

4Department of Pharmaceutics, Mashhad University of Medical Sciences, Mashhad,

Iran.

5Department of Statistics, Mashhad University of Medical Sciences, Mashhad,

Iran.

6Department of Dermatology and Plastic Surgery, Azad Islamic University of

Mashhad, Mashhad, Iran.

Address correspondence to:

Talat Khadivzadeh, M.Sc.

School of Nursing and Midwifery

Ebne Sina Street

Mashhad,

Iran

E-mail:

 

Abstract

 

Objective: The aim of this study was to determine the effects of Hypericum

perforatum on cesarean wound healing and hypertrophic scar.

 

Design: This was a randomized, double-blind clinical trial study.

 

Setting: The study was conducted in Samen-Ol-Ae

 

mmeh (Pbuh) Hospital in Mashhad, Iran.

 

Subjects: The subjects included 144 women with surgical childbirth who had

eligible criteria.

 

Intervention: The participants were randomly assigned to three groups. The

treatment and placebo groups applied H. perforatum or placebo ointment 3 times a

day for 16 days based on consecutive coded ointments. The control group remained

without any intervention postoperatively.

 

Assessment: Wound healing was assessed on the 10th day postcesarean using the

REEDA scale (REEDA stands for redness, edema, ecchymosis, discharge, and

approximation), which had criteria including redness, edema, ecchymosis,

discharge, and approximation. On the 40th day, the degree of scarring was

assessed using the Vancouver scar scale including pigmentation, height,

pliability, and vascularity. The subjects were also asked some questions about

pain by using the Visual Analogue Scale and pruritus of scar.

 

Results: The mean age of all the study subjects was 23.50±4.03 and mean parity

was 1.23±0.48. There were significant differences in wound healing on the 10th

day (p<0.005) and scar formation on the 40th day postpartum (p<0.0001) between

treatment group with placebo and control groups. However, the placebo group had

no differences in wound healing (p=0.93) and scar formation (p=0.11) with the

control group. In addition, significantly lower pain and pruritus were reported

by the treatment group compared with the placebo and control groups on the 40th

day postpartum.

 

Conclusions: Topical application of H. perforatum is safe and can facilitate

cesarean wound healing and minimize formation of scar and its pain and pruritus.

 

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