Guest guest Posted July 10, 2006 Report Posted July 10, 2006 Hi All, & Tom, Tom Verhaeghe wrote: > here's the article ( " Effect of " Phased Whole AP Therapy " on Ability of > Daily Life in 63 Cases of Cerebral Infarction-induced Hemiplegia " ) for > you to review, Phil. Many thanks, Tom. My comments on my edited version of the paper are below. I invite discussion of my comments from those who may disagree with them. (1) This was a poorly randomised and analysed trial and its conclusions are invalid. (2) As Table 2 (below) shows, randomisation in this trial was poor, because the DEFORMED RATE in the Basic Tx Group was 10.5% higher than in the Phased Tx Group BEFORE Tx. Therefore, one would expect a poorer outcome in the Basic Tx Group BEFORE the trial was done! (3) As Table 1 (below) shows, the CHANGE in BI scores between the two treatments (28.51 units of improvement dt Phased Tx versus 26.64 units of improvement dt Basic Tx) were minimal and did NOT confirm that the Phased Tx was significantly better than the Basic (Control) Tx. (4) I conclude that the Basic Tx gave similar clinical outcomes to the much more complicated " Phased Whole AP Tx " . Also, this paper gave no proof that the Reinforcing and Reducing manoeuvres, used respectively on the unaffected and affected side, are necessary to elicit good clinical responses. (5) For basic AP Tx of cerebral infarction-induced hemiplegia, one could select 10-12 points/session from the points listed below, and alternate points between sessions every 1-2 days. If there is sensory paralysis, one can select Body Points/Extraordinary Points on the unaffected side. (a) Contralateral Scalp Motor Area; (b) Extraordinary Points: Bafeng (EX-UE10), Baxie (EX-UE9); Xiashaohai [1 " below HT03)] © Body Points: BL23, BL25, BL37, BL60; GB20, GB29, GB30, GB34, GB40; GV14; LI04, LI11, LI15; LV08; SI12; SJ01, SJ05, SJ14; SP10; ST31, ST36, ST41. If indicated by symptoms (aphasia, thoracic limb paralysis, pelvic limb paralysis, etc), points may be added from: BL40, BL57; CV23; GB31, GB39; GV15; HT03, HT05; KI03; LI10; OT05 (local points); PC07; SI03; SJ04, SJ17; SP06; ST04, ST06; Z_21 (Shanglianquan Above CV23 (Lianquan; Ridge Spring), on CV line, 1' above CV23), as in the Cookbook selections from http://homepage.eircom.net/~progers/ad2.htm below: 020300 brain, its functions & parts, meninges, polio, convulsions , memory, tetanus, CVA etc 53/477/.953 LI04 LI11 ST36 GB34 ST06 LI15 GB20 GB30 ST04 GV14 Citation Score 0.800 0.741 0.703 0.663 0.634 0.610 0.608 0.604 0.594 0.578 020350 CVA, polio, paralysis, hemiplegia 44/401/.964 LI04 LI11 ST36 GB34 ST06 GB30 ST04 LI15 TH05 GB39 Citation Score 0.858 0.792 0.767 0.743 0.731 0.719 0.684 0.656 0.618 0.616 021200 tongue, speech 38/179/.961 CV23 GV15 LI04 HT05 TH17 LI11 TH05 ST06 GB20 Z_21 Citation Score 0.732 0.641 0.600 0.501 0.397 0.392 0.389 0.345 0.310 0.247 040000 thoracic limb, its organs & functions 48/291/.983 LI11 LI15 TH05 LI04 SI03 TH04 HT03 PC07 LI10 OT05 Citation Score 0.978 0.879 0.842 0.792 0.688 0.669 0.608 0.606 0.604 0.604 070000 pelvic limb, its organs & functions 52/330/.965 GB34 ST36 GB30 SP06 BL60 BL40 BL57 GB39 GB31 KI03 Citation Score 0.940 0.884 0.841 0.809 0.793 0.773 0.751 0.735 0.691 0.687 (6) There is some evidence (elsewhere) that Electro-AP may be more effective than manual AP in paralysis cases. (7) AP therapy should be used to complement conventional treatment of stroke / cerebral infarction, and expert Rehab / Physiotherapy. Best regards, >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> >>>>>> Effect of " Phased Whole AP Therapy " on Ability of Daily Life in 63 Cases of Cerebral Infarction-induced Hemiplegia Guo Yuanqi , Chen Liyi 2, Zhou Lucjin , Li Hui ,Qu Xuanming 3 & Liu Dongsheng 3 Journal of Traditional 88 2006;26(2):88-91. 1Dept of AP, 2nd Clinical Medical College, Guangzhou U of TCM, Guangzhou 510120, China 2 4th Affiliated Hospital of Medical College, Jinan U, Guangzhou, China 3 Guangzhou U of TCM, Guangdong, China Published in: Journal of Traditional 2006; 26(2): 88-91. Objective: To observe the effect of " Phased Whole AP therapy " on the ability of daily life (ADL) of patients with cerebral infarction-induced hemiplegia. Methods: 113 patients were randomly divided into a Tx with traditional Group (n=63) treated with Phased Whole AP and a control Group (n=50) treated with traditional AP. After the Tx, the improvement of ADL was compared between the two Groups. Results: Patients in the Tx Group obtained satisfactory therapeutic results in ADL improvement and in lowering of deformed rate, which were superior to those in the control Group. Conclusion: The Phased Whole AP is an effective therapy in treating cerebral infarction-induced hemiplegia, which can better improve the life quality of the patients. By adopting the internationally-acknowledged method for evaluating the ability of daily life (ADL), authors had from Apri1 2001 to April 2004 observed the effect of Phased Whole AP on ADL in patients with cerebral infarction-induced hemiplegia, and compared the findings with those of traditional AP. It is reported as follows. Clinical Data: 118 cases of cerebral infarction-induced hemiplegia were inpatients from the Department of Neuronal Internal Medicine and the Department of AP, The Second Clinical Medical College, Guangzhou University of TCM. They were randomly divided into a Tx Group (n=65) and a control Group (n=53). There were 5 cases (2 cases in the Tx Group and 3 cases in the control Group) that failed to be followed in the whole process. Phased Tx Group Basic Tx (Control) Group Number of patients 63 50 Gender 31M 32F 28M 22F Age (Years) 63.839.69 65.747.72 days in the course of disease 2.482.68 2.944.72 days to initiation of needling 4.974.22 4.023.96 scores in previous history 6.682.56 6.862.46 accumulated scores for accompanying diseases 6.98 3.69 7.12 3.76 Chi2 test and t test showed that the two Groups were comparable in gender, age, course of diseases initiation of needling, accumulated scores for previous history and accompanying diseases (P>0.05). 1. Criteria for Dx: The Criteria for Evaluation of the Therapeutic Effects for Apoplexy formulated by the Cooperation Group for Acute Cerebral Diseases, State Administration of TCM in 1995 were used for TCM Dx, and the criteria for " atherosclerotic thrombotic cerebral infarction " in the Essentials for Dx of Various Kinds of Cerebrovascular Diseases revised at the 4th National Conference on Cerebrovascular Diseases in 1995 were adopted for Dx in western medicine. 2. Criteria for recruitment: Included in the observations were those who accorded with the above-mentioned TCM/western diagnostic criteria, with cerebral infarction at the basal ganglia defined by cranial CT/MRI, with ages <75 years, with the first attack within a week and with consciousness and a stable disease condition. 3. Criteria for exclusion: Excluded in the observation were (1) those whose disease was induced by cerebral tumour, cerebral trauma, cerebral parasitosis, metabolism disorder, rheumatic cardiac disease, coronary heart disease and other heart disease complicated with atrial fibrillation; (2) those who had such severe complications as severe psychiatric disorder, severe dementia, and those who were complicated with severe primary diseases in the heart, liver, kidney, haemopoietic and endocrine system; (3) those who had severe dysfunction in language comprehension, and (4) those who had disorders severely affecting the movement of the limbs like joint pathological changes. Tx Methods 1) Basic AP Tx (Control) Group: According to AP Therapy compiled by Prof. Yang Changsen, points selected were contralateral motor area on the scalp, plus SJ14, LI11, LI04, GB30, GB34, ST36, ST41 and BL60 on the affected side. For points on the scalp, the needles were inserted horizontally with rotating manoeuvre. For body points, the needles were inserted perpendicularly, and the lifting and thrusting manoeuvre was applied with the reducing method being used during acute stage and reinforcing manoeuvre during the convalescence stage. 2) " Phased Whole AP " Tx Group: Based on Brunnstrom, point selection was made at different stages in the following ways: At the flaccid paralysis stage (stage 1 and 2), bilateral GB20, bilateral BL23, bilateral BL25 and GV14 were added in addition to the general points mentioned above. 10-12 points were alternatively taken each time, and ST36, LI11 and LI04 on the unaffected side were added at the same time. Reinforcing and reducing manoeuvres were used respectively on the unaffected and affected side. At the spasmodic stage (stage 3 and 4), points of the Hand-Shaoyang Meridian in the upper limbs and those of the Foot-Yangming and Foot- Jueyin Meridians in the lower limbs were used mainly. SI12, LI15, SJ01, SJ05, Baxie (EX-UE9), ST31, GB29, ST36, GB40, LV08 and Bafeng (EX-UE10) on the affected side were selected alternatively according to the condition of the patients. A reinforcing manoeuvre with a strong stimulating intensity was adopted. Also, Xiashaohai, [l“ below HT03)], BL37 and SP10 were added with a reducing manoeuvre. At the convalescence stage (stage 5 and 6), the same points as those in the control Group were used. Uniform reinforcing and reducing manoeuvre was used with a mild/moderate stimulating intensity. Needles were retained for 30 minutes, during which manipulation was performed once every 10 minutes. Tx was given once daily except Sunday. The therapeutic effect was estimated after 4 weeks of Tx. Apart from the basic Tx for patients in both Groups, functional Rehab should be added. At the flaccid paralysis stage, strengthened medical care was given to make the affected limbs in a right position and a proper body posture in bed should be adopted and the body posture shifted regularly to prevent spasm. Also, patients were encouraged to do active exercises on bed, such as bridge-like exercise, leg splint exercise, stretching/bending of the upper limb and the elbow. At the spasmodic stage, training should be carried out to avoid spasm, and massage was applied to relieve the spasm of joints and muscles. At the convalescence stage, patients should be asked to do the selective active and speedy exercises, such as 3-grade sitting positions, balanced standing, walking up and down the stairs. Besides, the training for controlling muscular spasm was also made continuously. The ability of daily life (ADL) was scored and estimated by adopting Barthel Index (BI). Clinical data were collected before Tx and 4 weeks after Tx. The t-test was used for numerical analysis, and Chi2 test used for comparison of rates. SPSS 11.0 software was used for statistical analysis. Criteria for Therapeutic Effects: Ability of daily life: According to BI scoring method, the improvement of ADL was evaluated in both Groups. 2) Evaluation of deformity: Based on BI scores, ADL was classified into deformed (BL<75) and non-deformed (BL=/>75). And the deformed rates were compared between the two Groups. Therapeutic Results: Comparison of BI scores before and after Tx in both Groups: As is shown in Table 1, there was no significant difference in BI scores between the two Groups before Tx (P>.05). After Tx, the BI scores were significantly elevated (P<.01) in both Groups, but the elevation in the Tx Group was obviously higher than that in the control Group with significant difference (P<.01), indicating that the " Phased Whole AP " was superior to the traditional AP in elevating ADL. Table 1. Comparison of BI scores between the two Groups before and after Tx (X+/-s) Group n Before Tx After Tx Mean BI Change(**) Phased Tx 63 53.57+/-29.07 82.08+/-19.31*$ 28.51 Basic Tx (Control) 50 43.34+/-29.58 69.98+/-27.53* 26.64 (*) P<.01, compared before v after Tx within Group ($) P<.01, compared between the 2 Groups (**) comment: The CHANGE in BI scores between the two treatments (28.51 units of improvement dt Phased Tx v 26.64 units of improvement dt Basic Tx) were minimal and did NOT confirm that the Phased Tx was significantly better than the Basic (Control) Tx. Comparison of deformed rates before and after the Tx: As is shown in Table 2, there was no significant difference in deformed rates before the Tx between the two Groups (P>.05), but after the Tx significant difference was found (P<.05), indicating that the " Phased Whole AP " was superior to the traditional AP in lowering the deformed rate. Table 2. Comparison of deformed rates between the two Groups before and after Tx Group n Before Tx Deformed Non-Deformed After Tx Deformed Non-Deformed Phased Tx 63 40 (63.5%) 23 (36.5%) 19 (30.2%) 44 (69.8%) Basic Tx (Control)* 50 37 (74.0%) 13 (26.0%) 25 (50.0%) 25 (50.0%) (*) comment: Randomisation in this trial was poor, because the DEFORMED RATE in the Basic Tx Group was higher than in the Phased Tx Group before Tx. Therefore, one would expect a poorer outcome in the Basic Tx Group BEFORE the trial was done! Discussion With improved level in Dx and Tx, apoplexy-induced mortality decreased greatly, but a higher deformed rate still remained. This deformity always resulted from the lowering/loss of ability of daily life due to diskinesia of the limbs. Modern Rehab medicine holds that it is more significant when estimation on motor is combined with estimation on ADL. Clinically, the BI scoring is a method that is used most widely and affectively to evaluate ADL. " Phased Whole AP " is a therapy composed of various kinds of AP methods, combined with modern Rehab training measures, in treating apoplexy-induced hemiplegia. It is composed of scalp-AP, traditional body AP, back-shu needling, opposing needling, and balanced needling in yin and yang meridians as well as functional Rehab training. This therapy should start at the early stage. At the flaccid paralysis stage (stages 1 and 2), scalp-AP is used together with body AP, with points selected both on the affected and the unaffected sides, especially back-shu points, aiming at putting more sensory and motor information to the brain and evoking active movement of the limbs to induce combined reaction and synergic movement to promote functional reformation of the brain, so as to modulate the lower centres. This way of emphasizing the back-shu points is beneficial to the restoration of trunk strength at the early paralyzed stage, so that it sets up a basis for further functional training. At the spasmodic stage (stages 3 and 4), AP Tx is mainly to inhibit spasm by way of combined point selection from yin and yang meridians with the points in antagonist muscles being selected to regulate balance between yin and yang and to inhibit muscular spasm. At the convalescence stage (stages 5 and 6), points are selected mainly according to differentiation and the points of the Yangming Meridian on the affected limb also are selected to dredge Qi & Xue in the affected limbs and to facilitate the establishment of a normal motor model. The combination of AP Tx and corresponding functional Rehab training has become a Rehab therapeutic model of TCM in treating apoplexy- induced hemiplegia, which is by means of integrated intervention, in which AP is taken as the main therapy. This model is in accord with natural pathological process of hemiplegia and conducive to restoration, " The Phased Whole AP therapy " is superior to traditional AP in lowering the deformed and handicapped rate, and in raising the ability of daily life of the patients, indicating further that it is a safe and effective AP therapy. Plasticity of the CNS may be involved in the mechanisms. By means of considerable repeated benign stimulations, Phased Whole AP may enhance the ability of structural and functional compensation and functional reformation of the CNS, hence a remarkable therapeutic effects. References 1. . ..1996; 29 ( 6 ): 381-383. 2. . , 1996;19(1): 55-56. 3. . . 1997;17( 5):312. 4. Duncan PW, Jorgensen HS, Wade DT. Outcome measures in acute stroke trials. A systematic review and some recommendations to improve practice. Stroke 2000; 31 (6):1429-1438. (Translated by Chen Zhengqiu ) >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> Best regards, HOME + WORK: 1 Esker Lawns, Lucan, Dublin, Ireland Tel: (H): +353-(0) or (M): +353-(0) < " Man who says it can't be done should not interrupt man doing it " - Chinese Proverb Quote
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