Herbal ingredients in QFGJS (Qing-Fu-Guan-Jie-Shu)

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Hi All,

 

Do you know the herbal ingredients in QFGJS (Qing-Fu-Guan-Jie-Shu). I

cannot find them on WWW.

 

Cai X, Zhou H, Wong YF, Xie Y, Liu ZQ, Jiang ZH, Bian ZX, Xu HX, Liu L.

Suppression of the onset and progression of collagen-induced arthritis in

rats by QFGJS, a preparation from an anti-arthritic Chinese herbal formula.

J Ethnopharmacol. 2006 Sep 16; [Epub ahead of print] Research and

Development Division, School of , Hong Kong Baptist

University, Kowloon Tong, Kowloon, Hong Kong, China. QFGJS (Qing-Fu-

Guan-Jie-Shu) is an herbal preparation, and its pronounced effectiveness in

treating adjuvant-induced arthritis (AIA) has been previously demonstrated.

We herein aimed to confirm its anti-arthritic effect on collagen-induced

arthritis (CIA) in rats. CIA was established in female Wistar rats with

intradermal injection of type II bovine collagen at the base of the tail of

animals. CIA rats were treated daily with oral administration of different

doses of QFGJS beginning on the day of the induction of arthritis (day 0, the

prophylactic treatment) or on the day after the onset of arthritis (day 13, the

therapeutic treatment) until day 30. The results showed that prophylactic

treatment with QFGJS significantly suppressed the onset of arthritis, and

therapeutic treatment with QFGJS markedly reduced paw swelling and ESR

levels even in the established CIA. Radiologic and histopathologic changes

in the arthritic joints were also significantly reduced in the QFGJS-treated

versus vehicle-treated rats. Moreover, the serum levels of pro-inflammatory

cytokines TNF-alpha, IL-1beta, and IL-6 were markedly lowered in the

QFGJS-treated rats. Hence, our studies demonstrate the quality, safety,

and effectiveness of QFGJS as an anti-arthritic agent, which makes QFGJS

a strong candidate for further clinical trials on rheumatoid arthritis (RA)

patients. PMID: 17049776 [PubMed - as supplied by publisher]

 

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