Guest guest Posted November 1, 2006 Report Share Posted November 1, 2006 Hi All, Early in Jan 2005 we discussed a very poor trial on acupuncture in hypertension in which a Dr Norman Kaplan (who has no publications of worth in any aspect of acupuncture - see: http://tinyurl.com/u5low ) was an author. Having received a copy of the original report from Sean Walsh, it was my opinion that no reputable peer-reviewed journal would accept that paper. It seems that the journals agreed with that opinion. Kaplan himself wrote [ Acupuncture for Hypertension?: Can 2500 Years Come to an End Kaplan, Norman M. http://www.saha.org.ar/articulos/acupuncture.htm ] " With only a fraction of the money and personnel used in the SHARP trial, we tried such a study but, not surprising, in retrospect, we failed, producing only an abstract 2 that, as a manuscript, could never find a place in a reputable journal. " . However, Kaplan persists in his attempt to discredit AP as a therapy for hypertension. See the article, above and http://tinyurl.com/u5low Unfortunately, he can now cite the results of a much larger trial (Macklin et al (abstract below) to support his thesis: Macklin EA, Wayne PM, Kalish LA, Valaskatgis P, Thompson J, Pian-Smith MCM, Zhang Q, Stevens S, Goertz C, Prineas RJ, Buczynski B, Zusman RM. Stop Hypertension with the Acupuncture Research Program (SHARP): results of a randomized controlled clinical trial. Hypertension. 2006;48:838-845. Abstract : Case studies and small trials suggest that acupuncture may effectively treat hypertension, but no large randomized trials have been reported. The Stop Hypertension with the Acupuncture Research Program pilot trial enrolled 192 participants with untreated blood pressure (BP) in the range of 140/90 to 179/109 mm Hg. The design of the trial combined rigorous methodology and adherence to principles of traditional Chinese medicine. Participants were weaned off antihypertensives before enrollment and were then randomly assigned to 3 treatments: individualized traditional Chinese acupuncture, standardized acupuncture at preselected points, or invasive sham acupuncture. Participants received <=12 acupuncture treatments over 6 to 8 weeks. During the first 10 weeks after random assignment, BP was monitored every 14 days, and antihypertensives were prescribed if BP exceeded 180/110 mm Hg. The mean BP decrease from baseline to 10 weeks, the primary end point, did not differ significantly between participants randomly assigned to active (individualized and standardized) versus sham acupuncture (systolic BP: -3.56 versus -3.84 mm Hg, respectively; 95% CI for the difference: -4.0 to 4.6 mm Hg; P=0.90; diastolic BP: -4.32 versus - 2.81 mm Hg, 95% CI for the difference: -3.6 to 0.6 mm Hg; P=0.16). Categorizing participants by age, race, gender, baseline BP, history of antihypertensive use, obesity, or primary traditional Chinese medicine diagnosis did not reveal any subgroups for which the benefits of active acupuncture differed significantly from sham acupuncture. Active acupuncture provided no greater benefit than invasive sham acupuncture in reducing systolic or diastolic BP. No doubt the Quackbuster lobby will hail Kaplan as an expert in acupuncture who now believes it is worthless in hypertension. Back to the bunker again! Best regards, Quote Link to comment Share on other sites More sharing options...
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